Team:Hong Kong HKUST/projectdescription

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The conversion of carbohydrates or protein into fat uses 10 times more calories of energy than simply storing fat in a fat cell*. This brought us attention to one method of burning calories - increase energy expenditure by converting fat into glucose. However, mammals cannot convert fatty acids into carbohydrate due to lack of glyoxylate enzymes, while plants and bacteria can. We planned to introduce glyoxylate enzymes into mammalian cells and introduce an artificial futile cycle.<br><br>
The conversion of carbohydrates or protein into fat uses 10 times more calories of energy than simply storing fat in a fat cell*. This brought us attention to one method of burning calories - increase energy expenditure by converting fat into glucose. However, mammals cannot convert fatty acids into carbohydrate due to lack of glyoxylate enzymes, while plants and bacteria can. We planned to introduce glyoxylate enzymes into mammalian cells and introduce an artificial futile cycle.<br><br>

Revision as of 03:21, 8 August 2013

*http://science.howstuffworks.com/life/cellular-microscopic/fat-cell2.htm