Team:LZU-China/Project

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         <h1>指导老师</h1>
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         <a href="#h-Design & Device"><h1>Design & Device</h1></a>
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         <a href="#h-Expriments"><h1>Expriments</h1></a>
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<h2> <span class="mw-headline" id="h-Design & Device">Design & Device</span></h2>
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<h3> <span class="mw-headline" id="Promoter">Promoter: 4 copies of NFκB gene </span></h3>
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On the basis of NF-κB signaling pathway and its feedback loop dynamics, we provided a device: A high-throughput drug screening system. The system is used to screen targeted drugs in NF-κB signaling pathway and lasts even longer. Natrually, we could  estimate whether the kind of drug is good or not.
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<br><br>NF-κB is a DNA binding protein, which means that the dimer could recognize a certain gene sequence and bind with it. Thus, we designed a four coupies of NF-κB gene sequence as the promoter. The downstream gene IκB flag with GFP, which could be a controller in tumor invading，moreover ， easy to observe.
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<h2> <span class="mw-headline" id="h-Expriments">Expriments</span></h2>
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Revision as of 16:39, 27 September 2013

progect

Design & Device

Promoter: 4 copies of NFκB gene

On the basis of NF-κB signaling pathway and its feedback loop dynamics, we provided a device: A high-throughput drug screening system. The system is used to screen targeted drugs in NF-κB signaling pathway and lasts even longer. Natrually, we could estimate whether the kind of drug is good or not.


NF-κB is a DNA binding protein, which means that the dimer could recognize a certain gene sequence and bind with it. Thus, we designed a four coupies of NF-κB gene sequence as the promoter. The downstream gene IκB flag with GFP, which could be a controller in tumor invading，moreover ， easy to observe.

Expriments

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E-mail:hwang2013@lzu.edu.cn
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