Team:LZU-China/Project

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<h3> <span class="mw-headline" id="Promoter">Promoter: 4 copies of NFκB gene </span></h3>
<h3> <span class="mw-headline" id="Promoter">Promoter: 4 copies of NFκB gene </span></h3>
On the basis of NF-κB signaling pathway and its feedback loop dynamics, we provided a device: A high-throughput drug screening system. The system is used to screen targeted drugs in NF-κB signaling pathway and lasts even longer. Natrually, we could  estimate whether the kind of drug is good or not.  
On the basis of NF-κB signaling pathway and its feedback loop dynamics, we provided a device: A high-throughput drug screening system. The system is used to screen targeted drugs in NF-κB signaling pathway and lasts even longer. Natrually, we could  estimate whether the kind of drug is good or not.  
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<br><img src="https://static.igem.org/mediawiki/2013/0/0c/IMG_6928.jpg"/>
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<br><img src="https://static.igem.org/mediawiki/2013/6/64/LZU-China_Project_1.png"/>
<br><br>NF-κB is a DNA binding protein, which means that the dimer could recognize a certain gene sequence and bind with it. Thus, we designed a four coupies of NF-κB gene sequence as the promoter. The downstream gene IκB flag with GFP, which could be a controller in tumor invading,moreover , easy to observe.
<br><br>NF-κB is a DNA binding protein, which means that the dimer could recognize a certain gene sequence and bind with it. Thus, we designed a four coupies of NF-κB gene sequence as the promoter. The downstream gene IκB flag with GFP, which could be a controller in tumor invading,moreover , easy to observe.

Revision as of 01:32, 28 September 2013

progect

Design & Device

Promoter: 4 copies of NFκB gene

On the basis of NF-κB signaling pathway and its feedback loop dynamics, we provided a device: A high-throughput drug screening system. The system is used to screen targeted drugs in NF-κB signaling pathway and lasts even longer. Natrually, we could estimate whether the kind of drug is good or not.


NF-κB is a DNA binding protein, which means that the dimer could recognize a certain gene sequence and bind with it. Thus, we designed a four coupies of NF-κB gene sequence as the promoter. The downstream gene IκB flag with GFP, which could be a controller in tumor invading,moreover , easy to observe.

Expriments

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