Team:Nanjing-China/abstract

From 2013.igem.org

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Atrazine, a widely used herbicide, persists for a long period in the environment onced used. It causes metabolic disorders in both animals and humankind. Our team utilized the ribosome switch induced by atrazine, a QS system of Plux and a degrading enzyme to control E.coil's motility through regulating its CheZ gene. Therefore, E.coli can recognize atrazine, recruit team workers, and degrade atrazine. Our team found a transporter of atrazine, which we call TRM. We also mutated the degrading enzyme, TrzN, making it better at degradation. We combined TRM and the TrzN to improve atrazine absorbance and degradation. Moreover, our team are trying to analyze and compare several systems with computer, hoping to find the best one which is equipped with faster moving and quicker degrading. Overall,we believe our system will boost the industrialization, universalization as well as standardization in the field of treatment for atrazine and other versatile small molecules.  
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Atrazine, a naughty demon who plays around in the soil, is considerably hard to be eliminated. Its spell causes metabolic disorders in many species.<br><br>
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Our elf combined a smart atrazine radar, an amazing transporter, a recruiting system and a degrading enzyme to hunt down this die-hard. With our system, E.coli can recognize atrazine, recruit team members, and eliminate atrazine.<br><br>
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Our team found the brand new transporter, TRM, from the genome of a bacteria which can utilize atrazine as its only carbon source. With this transporter, the sensitivity of our system and the degrading efficiency are both improved. We also mutated the degrading enzyme, TrzN, to make it better at degrading atrazine than the natural enzyme. We then combined the TRM and the mutated TrzN to achieve a more satisfying result.<br><br>
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To take a further step, our team has been devoting ourselves to analyzing and comparing several systems simulated by computer, and we successfully located on the best solution which is equipped with faster moving and quicker degrading.<br><br>
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Overall, we believe that our system has provided a brilliant solution to make this world a better place for creatures on this planet, hoping it can also become a sincere compensation for the damage resulting from this naughty demon created by ourselves.<br>
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Latest revision as of 06:18, 27 October 2013

Abstract
Atrazine, a naughty demon who plays around in the soil, is considerably hard to be eliminated. Its spell causes metabolic disorders in many species.

Our elf combined a smart atrazine radar, an amazing transporter, a recruiting system and a degrading enzyme to hunt down this die-hard. With our system, E.coli can recognize atrazine, recruit team members, and eliminate atrazine.

Our team found the brand new transporter, TRM, from the genome of a bacteria which can utilize atrazine as its only carbon source. With this transporter, the sensitivity of our system and the degrading efficiency are both improved. We also mutated the degrading enzyme, TrzN, to make it better at degrading atrazine than the natural enzyme. We then combined the TRM and the mutated TrzN to achieve a more satisfying result.

To take a further step, our team has been devoting ourselves to analyzing and comparing several systems simulated by computer, and we successfully located on the best solution which is equipped with faster moving and quicker degrading.

Overall, we believe that our system has provided a brilliant solution to make this world a better place for creatures on this planet, hoping it can also become a sincere compensation for the damage resulting from this naughty demon created by ourselves.