Team:Penn

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<br><center><a href = 'https://docs.google.com/forms/d/188iefj_j6gBvrHC0IS3rG2zBelaVuy-JddYNN7QF8_Y/viewform'>Interested in joining the team? Submit your application for Penn iGEM 2014 here. </a></center>
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<TR><TD ALIGN="center"><a href='https://2013.igem.org/Team:Penn/MaGellinToolbox'><IMG SRC="http://farm6.staticflickr.com/5523/10529365546_355d2fe7fc.jpg" width="240" height="auto"></a></TD></TR>
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</TABLE><br><a href='https://2013.igem.org/Team:Penn/MaGellinToolbox'>Constructed a toolbox for developing site-specific DNA methylases</a></TD>
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<TR><TD ALIGN="center"><a href='https://2013.igem.org/Team:Penn/AssayOverview'><IMG SRC="http://farm3.staticflickr.com/2836/10529350575_dfb38e3538.jpg" width="240" height="auto"></a></TD></TR>
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</TABLE><br><a href='https://2013.igem.org/Team:Penn/AssayOverview'>Created a standardized assay for site-specific methylases</a></TD>
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<TR><TD ALIGN="center"><a href='https://2013.igem.org/Team:Penn/Software'><IMG SRC="http://farm4.staticflickr.com/3742/10529401844_cc5f713a48.jpg" width="240" height="auto"></a></TD></TR>
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</TABLE><br><a href='https://2013.igem.org/Team:Penn/Software'>Developed software to automate analysis of our assay</a></TD>
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<h2>Accomplishments:</h2>
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Our goal was to enable epigenetic engineering. We believe synthetic biological systems should be as subtle and robust as natural occurring counterparts. Moreover, we wanted to begin development on much-needed second-generation epigenetic therapeutics.</b><br/>
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<li><a href="https://2013.igem.org/Team:Penn/FusionMotivation">Designed a functional fusion protein to facilitate epigenetic engineering, with numerous advantages over existing technologies</a></li>
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<li><a href="https://2013.igem.org/Team:Penn/MaGellinMotivation">Validated a novel methylation assay, MaGellin, to accelerate development of epigenetic engineering tools</a></li>
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<TR><TD ALIGN="center"><a href='https://2013.igem.org/Team:Penn/MethylaseOverview'><IMG SRC="http://farm6.staticflickr.com/5478/10529350195_2c54c496e5.jpg" width="240" height="auto"></a></TD></TR>
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<li><a href="https://2013.igem.org/Team:Penn/MaGellinSoftware">Built a complementary MaGellin software package to automate experimental analysis</a></li>
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</TABLE><br><a href='https://2013.igem.org/Team:Penn/MethylaseOverview'>Designed and characterized a novel TALE-methylase fusion protein</a> <br></TD>
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<li><a href="https://2013.igem.org/Team:Penn/Biobricks">BioBrick'ed our MaGellin plasmid so other iGEM teams can build off our work</a></li>
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<li><a href="https://2013.igem.org/Team:Penn/Too_Soon_To_Treat">Wrote an article on the ethical implications of epigenetic interventions, accepted for publication in the "nation's premier peer-reviewed undergraduate bioethics journal" </a></li>
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<li><a href="https://2013.igem.org/Team:Penn/LIMS">Developed an open-source Laboratory Information Management System to help teams keep their labs organized </a></li>
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<li><a href="https://2013.igem.org/Team:Penn/Outreach">Promoted iGEM, synthetic biology, and our research at numerous outreach events to inspire future scientists</a></li>
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<li>Featured in an <a href="http://mackinstitute.wharton.upenn.edu/2013/its-not-all-in-the-dna-penn-team-benefits-from-mack-institute-sponsorship-in-synthetic-biology-competition/">interview</a></li>
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<TR><TD ALIGN="center"><a href='https://2013.igem.org/Team:Penn/hpoverview'><IMG SRC="http://farm4.staticflickr.com/3670/10529586493_833c6216ee.jpg" width="240" height="auto"></a></TD></TR>
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</TABLE><br><a href='https://2013.igem.org/Team:Penn/hpoverview'>Introduced synthetic biology to the community</a></TD>
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<TR><TD ALIGN="center"><a href='https://2013.igem.org/Team:Penn/Too_Soon_To_Treat'><IMG SRC="http://farm4.staticflickr.com/3815/10529365086_82d164e2b1.jpg" width="240" height="auto"></a></TD></TR>
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</TABLE><br><a href='https://2013.igem.org/Team:Penn/Too_Soon_To_Treat'>Published an article on the ethics of epigenetic engineering</a></TD>
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<TR><TD ALIGN="center"><a href='https://2013.igem.org/Team:Penn/Team'><IMG SRC="http://farm6.staticflickr.com/5533/10529401504_677c4f296a.jpg" width="240" height="auto"></a></TD></TR>
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</TABLE><br><a href='https://2013.igem.org/Team:Penn/Team'>Our team</a> <br> <br> <br></TD>
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<TR><TD ALIGN="center"><a href='https://2013.igem.org/Team:Penn/Achievements'><IMG SRC="http://farm4.staticflickr.com/3739/10529350025_2db22731e9.jpg" width="240" height="auto"></a></TD></TR>
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</TABLE><br><a href='https://2013.igem.org/Team:Penn/Achievements'>Grand Prize Winner, North America<br>Best Experimental Measurement Approach, North America</a></TD>
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<TR><TD ALIGN="center"><a href='http://articles.philly.com/2013-11-27/news/44490110_1_synthetic-biology-research-project-international-genetically-engineered-machine'><IMG SRC="http://farm8.staticflickr.com/7397/10529350205_c12e2cd367.jpg" width="240" height="auto"></a></TD></TR>
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</TABLE><br><a href='http://articles.philly.com/2013-11-27/news/44490110_1_synthetic-biology-research-project-international-genetically-engineered-machine'>Featured in a Philadelphia Inquirer article</a> <br> <br> <br></TD>
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Latest revision as of 16:42, 15 January 2014

Penn iGEM