Team:Penn

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Penn iGEM

Accomplishments:


Our goal was to enable epigenetic engineering. We believe synthetic biological systems should be as subtle and robust as natural organisms.

  1. Designed a functional fusion protein to facilitate epigenetic engineering
  2. Validated a novel methylation assay, MaGellin, to accelerate development of epigenetic engineering tools
  3. Built a complementary MaGellin software package to automate experimental analysis
  4. BioBrick'ed our MaGellin plasmid so other iGEM teams can build off our work
  5. Wrote an article on the ethical implications of epigenetic interventions, accepted for publication in the "nation's premier peer-reviewed undergraduate bioethics journal"
  6. Developed an open-source Laboratory Information Management System to help teams