Team:Stanford-Brown

From 2013.igem.org

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<span id="abs-title" style="margin-top:-30px;"><a href="/Team:Stanford-Brown/Team/Apply">JOIN US IN 2014! CLICK HERE!</a></span>
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             <span id="abs-title">ABSTRACT</span>
             <span id="abs-title">ABSTRACT</span>
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Communication is a dynamic requirement for life as we know it. We are using cellular and molecular messaging of different magnitudes to improve the broadcasting and reception of information. Starting on the atomic level, our <b>BioWires</B> project has created silver-incorporating DNA to act as nanowires, which could improve the cost and effectiveness of electronic products. Our <b>CRISPR</B> project is creating a system for  DNA messages and resistances to be passed from cell to cell, in effect, creating transmissible probiotics and changing the way that cells communicate. We are also building a chromogenic biosensor to detect sucrose secretion that will be launched on a satellite (<b>EuCROPIS</B>) into low-Earth orbit. Finally, our <B>De-Extinction</B> project involves decoding messages from the past to better understand early life on Earth.<br><br>
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Communication is an integral part of life as we know it. This summer, we pursued four synthetic biology projects with the goal of improving communication across different mediums. On the atomic level, our <b>BioWires</B> project has created silver-incorporating DNA strands to use as nanowires, which could improve the cost and effectiveness of electronics. Our <b>CRISPR</B> project worked on a system for  passing DNA regulatory messages between cells, in effect creating transmissible vaccines. We also extrapolated proteins from the past to better understand early life on Earth for our <B>De-Extinction</B> project. Finally, we built a sucrose biosensor in <I>B. subtilis</I> that will be launched on the <b>EuCROPIS</B> satellite  into low-Earth orbit. <br><br>
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<big><B>We are the Stanford-Brown iGEM team, and we're connecting life on Earth to help us prepare for life beyond it.</B></big>
<big><B>We are the Stanford-Brown iGEM team, and we're connecting life on Earth to help us prepare for life beyond it.</B></big>
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             <div style="margin-top:15px; text-align:center; font-weight: 600; font-size: 18px;">ACCOMPLISHMENTS</div>
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             <div style="margin-top:15px; text-align:center; font-weight: 600; font-size: 18px;">ACHIEVEMENTS</div>
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                 <li> <a href="#"> Isolated and bricked components of the CRISPR-Cas system</a></li>
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                 <li> <a href="/Team:Stanford-Brown/Projects/BioWires">Demonstrated silver-ion incorporation in the DNA double-helix </a></li>
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<li>improved on past attempts to extract CASCADE,CRISPR, and Cas3 using novel cloning techniques</li>
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                 <li> <a href="/Team:Stanford-Brown/Projects/EuCROPIS">Worked with NASA and the German Space agency to develop BioBrick constructs for the EuCROPIS Satellite Mission</a></li>
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                <li> <a href="/Team:Stanford-Brown/Projects/CRISPR">Isolated and bricked components of two CRISPR-Cas systems</a></li>
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                 <li> <a href="/Team:Stanford-Brown/Projects/De-Extinction">Designed and modeled ancestral proteins to understand early conditions of earth</a></li>
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                <li> <a href="#">Demonstrated Silver-ion incorporation in DNA double-helix </a></li>
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<li> <a href="/Team:Stanford-Brown/Projects/De-Extinction#Evolutionary_Modeling">Collaborated with Dr. Rich Lenski to use 25 years of evolutionary data to model and text bioinformatics software </li>
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                <li> <a href="/Team:Stanford-Brown/Projects/HumanPractices">Authored reports on the the ethics of de-extinction and the iGEM workflow </a></li>
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<li> Demonstrated charge shift via (technique) </li>
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                 <li> <a href="https://2013.igem.org/Team:UC_Davis/Database/Initial_Population">Collaborated with team UC Davis to characterize promoter strengths</a></li>
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<li> <a href="https://2013.igem.org/Edinburgh_University">Consulted with Team Edinburgh on <i>B. subtilis</i> methods and protocols </li>
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                 <li> <a href="#">Worked with NASA and the German Space agency to develop B. subtilis for the EuCROPIS Satellite Mission
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<li> <a href="https://2013.igem.org/Team:Stanford-Brown/Team/Outreach#Teaching_a_BioEngineering_Bootcamp">Instructed high school seniors in the basics of synthetic biology and how to build an iGEM team </li>
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</a></li>
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<li> <a href="https://2013.igem.org/Team:Stanford-Brown/Team/Outreach#Bay_Area_and_NYC_Maker_Faires">Demonstrated SynBio and iGEM to the public at Maker Faire in SF and NYC </li>
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                 <li> <a href="/Team:Stanford-Brown/HumanPractices/Introduction"> Designed and modeled the function of ancestral proteins to understand early conditions of earth</a></li>
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<li> <a href="http://www.facebook.com/IgemMemes">Curated iGEM memes with additional social outreach via Instagram and Twitter </li>
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                <li> <a href="http://www.wired.com/wiredscience/2012/08/engineering-bacteria-for-mars/">Ethics of De-extiction and authored guides on the workflow of iGEM </a></li>
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<li> <a href="https://2013.igem.org/Team:Stanford-Brown/Team/Outreach#Podcasts_and_Memes">Produced iGEM podcast to discuss SynBio topics </li>
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                 <li> <a href="http://www.facebook.com/IgemMemes">Worked with team UC Davis to characterize promoter strengths</a></li>
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<li> Worked with Team Ediburgh to develop B. subtilis </li>
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<li> Instructed high school seniors in the basics of synthetic biology and how to construct an iGEM team </li>
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<li> Explained/demonstrated synbio and iGEM to thepublic at Maker Faire in SF and NYC </li>
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<li> Curated iGEM memes with additional social outreach via Instagram and Twitter </li>
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<li> Produced iGEM podcast to discuss Synbio topics </li>
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             <div class="feature"><a href="https://2013.igem.org/Team:Stanford-Brown/Projects/BioWires"><img src="https://static.igem.org/mediawiki/2013/d/de/BioWires_logo2.png" width="210"/></a>
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             <div class="feature"><iframe width="210" height="160" src="//www.youtube.com/embed/RNHHZBTr7Ow?rel=0" frameborder="0" allowfullscreen></iframe>
             <p class="brief">Atomic Communication
             <p class="brief">Atomic Communication
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           <div class="feature"><a href="https://2013.igem.org/Team:Stanford-Brown/Projects/De-Extinction"><img src="https://static.igem.org/mediawiki/2013/0/03/De-extinction2.jpg" width="210"/></a>
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             <p class="brief">Temporal Communication
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           <div class="feature"><iframe width="210" height="160" src="//www.youtube.com/embed/Zza9PVbyEbY?rel=0" frameborder="0" allowfullscreen></iframe>
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             <p class="brief">Cellular Communication
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           <div class="feature"><a href="https://2013.igem.org/Team:Stanford-Brown/Projects/Immunity"><img src="https://static.igem.org/mediawiki/2013/6/68/CRISPR.jpg" width="210" /></a>
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           <div class="feature"><iframe width="210" height="160" src="//www.youtube.com/embed/qaKvX7Z__0w?rel=0" frameborder="0" allowfullscreen></iframe>
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             <p class="brief">Cellular Communication
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             <p class="brief">Temporal Communication
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           <div class="feature"><a href="https://2013.igem.org/Team:Stanford-Brown/Projects/EuCROPIS"><img src="https://static.igem.org/mediawiki/2013/6/60/EuCROPIS2.jpg" width="210" /></a>
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           <div class="feature"><iframe width="210" height="160" src="//www.youtube.com/embed/_kOq22MqGrk?rel=0" frameborder="0" allowfullscreen></iframe>
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             <p class="brief">Inter-Species Communication
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             <p class="brief">Spatial Communication
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Latest revision as of 04:12, 16 November 2013

JOIN US IN 2014! CLICK HERE!
ABSTRACT

Communication is an integral part of life as we know it. This summer, we pursued four synthetic biology projects with the goal of improving communication across different mediums. On the atomic level, our BioWires project has created silver-incorporating DNA strands to use as nanowires, which could improve the cost and effectiveness of electronics. Our CRISPR project worked on a system for passing DNA regulatory messages between cells, in effect creating transmissible vaccines. We also extrapolated proteins from the past to better understand early life on Earth for our De-Extinction project. Finally, we built a sucrose biosensor in B. subtilis that will be launched on the EuCROPIS satellite into low-Earth orbit.

We are the Stanford-Brown iGEM team, and we're connecting life on Earth to help us prepare for life beyond it.

Atomic Communication

Cellular Communication

Temporal Communication

Spatial Communication