http://2013.igem.org/wiki/index.php?title=Team:TU-Delft/Modeling&feed=atom&action=historyTeam:TU-Delft/Modeling - Revision history2024-03-29T10:02:20ZRevision history for this page on the wikiMediaWiki 1.16.5http://2013.igem.org/wiki/index.php?title=Team:TU-Delft/Modeling&diff=297947&oldid=prevRbharathkumar at 17:23, 4 October 20132013-10-04T17:23:44Z<p></p>
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<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><p align = "justify">In order to simplify this modeling, we <del class="diffchange diffchange-inline">splitted </del>it up into three different modules which were used as building blocks for the final model. In this way the feasibility of the total model is more easily validated, as the building blocks can be validated independently. The three building blocks are:</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><p align = "justify">In order to simplify this modeling, we <ins class="diffchange diffchange-inline">split </ins>it up into three different modules which were used as building blocks for the final model. In this way the feasibility of the total model is more easily validated, as the building blocks can be validated independently. The three building blocks are:</div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div> <li> <a href="https://2013.igem.org/Team:TU-Delft/Timer_Plus_Sumo" style="text-decoration: none"" target="_blank"><font color="#0080FF" size="3">Timer plus SUMO</font></a> </li></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div> <li> <a href="https://2013.igem.org/Team:TU-Delft/Timer_Plus_Sumo" style="text-decoration: none"" target="_blank"><font color="#0080FF" size="3">Timer plus SUMO</font></a> </li></div></td></tr>
</table>Rbharathkumarhttp://2013.igem.org/wiki/index.php?title=Team:TU-Delft/Modeling&diff=289177&oldid=prevDimitra at 09:58, 4 October 20132013-10-04T09:58:48Z<p></p>
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<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>Modeling is the bridge between science and engineering in this project; using the scientific knowledge on our system, we can describe how the system will act and interact. Furthermore, using the <del class="diffchange diffchange-inline">qualitative </del>relations derived from the models the circuit has been adjusted and redesigned. This description is used for predicting what will happen in the lab, but also if the project can be applied in reality in a 'band-aid' product. Next to giving a preliminary design of the band-aid, new peptides are designed to give us the properties we want for this application.</p> </div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>Modeling is the bridge between science and engineering in this project; using the scientific knowledge on our system, we can describe how the system will act and interact. Furthermore, using the <ins class="diffchange diffchange-inline">quantitative </ins>relations derived from the models the circuit has been adjusted and redesigned. This description is used for predicting what will happen in the lab, but also if the project can be applied in reality in a 'band-aid' product. Next to giving a preliminary design of the band-aid, new peptides are designed to give us the properties we want for this application.</p> </div></td></tr>
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</table>Dimitrahttp://2013.igem.org/wiki/index.php?title=Team:TU-Delft/Modeling&diff=280937&oldid=prevJfkooijman at 18:43, 3 October 20132013-10-03T18:43:27Z<p></p>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>One of the most important parts of the project is to indicate the final application. For that reason, band aid modelling was performed. To be more specific, the idea of the final application is related to placing our engineered organism into a band aid.The band aid will be located on the wound. In that way, MRSA will be detected and the peptides will be produced and released through the band aid. By modelling the band aid, we are trying to answer questions like:</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>One of the most important parts of the project is to indicate the final application. For that reason, band aid modelling was performed. To be more specific, the idea of the final application is related to placing our engineered organism into a band aid.The band aid will be located on the wound. In that way, MRSA will be detected and the peptides will be produced and released through the band aid. By modelling the band aid, we are trying to answer questions like:</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div> <ol></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div> <ol></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"><li>Is it possible the AIPs to pass through the membrane in order to be possible for the E.coli to detect MRSA?</li></del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><li>If the MRSA is detected, is the amount of the produced peptide enough to kill it ?</li></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><li>If the MRSA is detected, is the amount of the produced peptide enough to kill it ?</li></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"><li>What is the maximum diameter of the pores in the membrane so as only the AIPs and the peptides to pass through?</li></del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><li>How many pores are necessary in order to be possible for the peptide to be released?</li></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><li>How many pores are necessary in order to be possible for the peptide to be released?</li></div></td></tr>
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</table>Jfkooijmanhttp://2013.igem.org/wiki/index.php?title=Team:TU-Delft/Modeling&diff=262640&oldid=prevMaithiliKrishnan at 19:47, 1 October 20132013-10-01T19:47:56Z<p></p>
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<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><h2 align="center">Modeling</h2></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><h2 align="center"<ins class="diffchange diffchange-inline">><br</ins>> Modeling</h2></div></td></tr>
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</table>MaithiliKrishnanhttp://2013.igem.org/wiki/index.php?title=Team:TU-Delft/Modeling&diff=133005&oldid=prevJfkooijman at 08:29, 18 September 20132013-09-18T08:29:49Z<p></p>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>By modelling the behavior of the circuit, we are finding answers for the following questions:</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>By modelling the behavior of the circuit, we are finding answers for the following questions:</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div> <ol></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div> <ol></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"><li>How many minutes does the cell lysis take from the point of induction?</li></ins></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><li>How much peptides are produced by the circuit?</li></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><li>How much peptides are produced by the circuit?</li></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><li>How much peptides are still uncleaved by the SUMO at the point of cell lysis?</li></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><li>How much peptides are still uncleaved by the SUMO at the point of cell lysis?</li></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"><li>How many minutes does the cell lysis take from the point of induction?</li></del></div></td><td colspan="2"> </td></tr>
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</table>Jfkooijmanhttp://2013.igem.org/wiki/index.php?title=Team:TU-Delft/Modeling&diff=131019&oldid=prevJfkooijman at 12:31, 17 September 20132013-09-17T12:31:22Z<p></p>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><li>How much peptides are produced by the circuit?</li></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><li>How much peptides are produced by the circuit?</li></div></td></tr>
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<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"><li>How many minutes does the cell lysis take from the point of induction?</li></ins></div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>color="#0080FF" size="3">novel peptides</font></a></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>color="#0080FF" size="3">novel peptides</font></a></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>which meet our specific needs: very toxic for <i>S.aureus</i> (very low MIC), not toxic for humans and <i>E.coli</i>. These properties we also had in mind by choosing from the existing peptides, but the matching peptides did not met the requirements that well. </div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>which meet our specific needs: very toxic for <i>S.aureus</i> (very low MIC), not toxic for humans and <i>E.coli</i>. These properties we also had in mind by choosing from the existing peptides, but the matching peptides did not met the requirements that well. </div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>In order to manage this, we performed data analysis and feature extraction of the existing experimentally validated datasets combined with <del class="diffchange diffchange-inline">associaton </del>rule mining.</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>In order to manage this, we performed data analysis and feature extraction of the existing experimentally validated datasets combined with <ins class="diffchange diffchange-inline">association </ins>rule mining.</div></td></tr>
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</table>Jfkooijmanhttp://2013.igem.org/wiki/index.php?title=Team:TU-Delft/Modeling&diff=127932&oldid=prevDimitra at 13:02, 16 September 20132013-09-16T13:02:37Z<p></p>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><p align = "justify">In order to simplify this modeling, we splitted it up into three different modules which were used as building blocks for the final model. In this way the feasibility of the total model is more easily validated, as the building blocks can be validated independently. The three building blocks are:</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><p align = "justify">In order to simplify this modeling, we splitted it up into three different modules which were used as building blocks for the final model. In this way the feasibility of the total model is more easily validated, as the building blocks can be validated independently. The three building blocks are:</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><ul style="list-style-type: circle"></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><ul style="list-style-type: circle"></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div> <li> <a href="https://2013.igem.org/Timer_Plus_Sumo" style="text-decoration: none"" target="_blank"><font color="#0080FF" size="3">Timer plus SUMO</font></a> </li></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div> <li> <a href="https://2013.igem.org<ins class="diffchange diffchange-inline">/Team:TU-Delft</ins>/Timer_Plus_Sumo" style="text-decoration: none"" target="_blank"><font color="#0080FF" size="3">Timer plus SUMO</font></a> </li></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div> <li> <a href="https://2013.igem.org/KillSwitch" style="text-decoration: none"" target="_blank"><font color="#0080FF" size="3">Kill Switch</font></a> </li></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div> <li> <a href="https://2013.igem.org<ins class="diffchange diffchange-inline">/Team:TU-Delft</ins>/KillSwitch" style="text-decoration: none"" target="_blank"><font color="#0080FF" size="3">Kill Switch</font></a> </li></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div> <li> <a href="https://2013.igem.org/Timer-<del class="diffchange diffchange-inline">SUMO</del>-KillSwitch" style="text-decoration: none"" target="_blank"><font </div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div> <li> <a href="https://2013.igem.org<ins class="diffchange diffchange-inline">/Team:TU-Delft</ins>/Timer-<ins class="diffchange diffchange-inline">Sumo</ins>-KillSwitch" style="text-decoration: none"" target="_blank"><font </div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>color="#0080FF" size="3">Timer-SUMO-KillSwitch (total circuit)</font></a> </li></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>color="#0080FF" size="3">Timer-SUMO-KillSwitch (total circuit)</font></a> </li></div></td></tr>
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</table>Dimitrahttp://2013.igem.org/wiki/index.php?title=Team:TU-Delft/Modeling&diff=127636&oldid=prevDimitra at 10:48, 16 September 20132013-09-16T10:48:44Z<p></p>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><li>If the MRSA is detected, is the amount of the produced peptide enough to kill it ?</li></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><li>If the MRSA is detected, is the amount of the produced peptide enough to kill it ?</li></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><li>What is the maximum diameter of the pores in the membrane so as only the AIPs and the peptides to pass through?</li></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><li>What is the maximum diameter of the pores in the membrane so as only the AIPs and the peptides to pass through?</li></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><li>How many pores are necessary in order to be possible <del class="diffchange diffchange-inline">enough </del>peptide to be released?</li></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><li>How many pores are necessary in order to be possible <ins class="diffchange diffchange-inline">for the </ins>peptide to be released?</li></div></td></tr>
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</table>Dimitrahttp://2013.igem.org/wiki/index.php?title=Team:TU-Delft/Modeling&diff=125215&oldid=prevJfkooijman at 12:29, 15 September 20132013-09-15T12:29:14Z<p></p>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><h2 align="center">Circuit modeling</h2></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><h2 align="center">Circuit modeling</h2></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><p align = "justify"></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><p align = "justify"></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>By modelling the <del class="diffchange diffchange-inline">band aid</del>, we are <del class="diffchange diffchange-inline">trying to answer </del>questions <del class="diffchange diffchange-inline">like</del>:</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>By modelling the <ins class="diffchange diffchange-inline">behavior of the circuit</ins>, we are <ins class="diffchange diffchange-inline">finding answers for the following </ins>questions:</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div> <ol></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div> <ol></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><li><del class="diffchange diffchange-inline">Is it possible </del>the <del class="diffchange diffchange-inline">AIPs to pass through the membrane in order to be possible for the E.coli to detect MRSA</del>?</li></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><li><ins class="diffchange diffchange-inline">How much peptides are produced by </ins>the <ins class="diffchange diffchange-inline">circuit</ins>?</li></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><li><del class="diffchange diffchange-inline">If </del>the <del class="diffchange diffchange-inline">MRSA is detected, is </del>the <del class="diffchange diffchange-inline">amount </del>of <del class="diffchange diffchange-inline">the produced peptide enough to kill it ?</li></del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><li><ins class="diffchange diffchange-inline">How much peptides are still uncleaved by </ins>the <ins class="diffchange diffchange-inline">SUMO at </ins>the <ins class="diffchange diffchange-inline">point </ins>of <ins class="diffchange diffchange-inline">cell lysis</ins>?</li></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del class="diffchange diffchange-inline"><li>What is the maximum diameter of the pores in the membrane so as only the AIPs and the peptides to pass through?</li></del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del class="diffchange diffchange-inline"><li>How many pores are necessary in order to be possible enough peptide to be released</del>?</li></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></ol></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></ol></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></p></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></p></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><p align = "justify">In order to simplify <del class="diffchange diffchange-inline">the </del>modeling <del class="diffchange diffchange-inline">of the complete circuit</del>, we splitted it up into three different modules which were used as building blocks for the final model:</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><p align = "justify">In order to simplify <ins class="diffchange diffchange-inline">this </ins>modeling, we splitted it up into three different modules which were used as building blocks for the final model<ins class="diffchange diffchange-inline">. In this way the feasibility of the total model is more easily validated, as the building blocks can be validated independently. The three building blocks are</ins>:</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><ul style="list-style-type: circle"></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><ul style="list-style-type: circle"></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div> <li> <a href="https://2013.igem.org/Timer_Plus_Sumo" style="text-decoration: none"" target="_blank"><font color="#0080FF" size="3">Timer plus SUMO</font></a> </li></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div> <li> <a href="https://2013.igem.org/Timer_Plus_Sumo" style="text-decoration: none"" target="_blank"><font color="#0080FF" size="3">Timer plus SUMO</font></a> </li></div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></p></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></p></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><p align = "justify"></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><p align = "justify"></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>Moreover, we <del class="diffchange diffchange-inline">performed </del>sensitivity analysis <del class="diffchange diffchange-inline">in order </del>to investigate which parameters most influence <del class="diffchange diffchange-inline">our models</del>.</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">In the total circuit model the questions stated above are answered. </ins>Moreover<ins class="diffchange diffchange-inline">, to indicate the validity of these answers</ins>, we <ins class="diffchange diffchange-inline">perform a </ins>sensitivity analysis to investigate which parameters most influence <ins class="diffchange diffchange-inline">the results. This gives an indication of the validity as some parameters are quite well known well others are less sure</ins>. </div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><h2 align="center">Application modeling (band-aid)</h2></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><h2 align="center">Application modeling (band-aid)</h2></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><p align = "justify"></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><p align = "justify"></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>One of the most important parts of the project is to indicate the final application. For that reason, band aid modelling was performed. To be more specific, the idea of the final application is related to placing our engineered organism into a band aid.The band aid will be located on the wound. In that way, MRSA will be detected and the peptides will be produced and released through the band aid. By modelling the band aid, we are trying to answer questions like:</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>One of the most important parts of the project is to indicate the final application. For that reason, band aid modelling was performed. To be more specific, the idea of the final application is related to placing our engineered organism into a band aid.The band aid will be located on the wound. In that way, MRSA will be detected and the peptides will be produced and released through the band aid. By modelling the band aid, we are trying to answer questions like:</div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><li>What is the maximum diameter of the pores in the membrane so as only the AIPs and the peptides to pass through?</li></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><li>What is the maximum diameter of the pores in the membrane so as only the AIPs and the peptides to pass through?</li></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><li>How many pores are necessary in order to be possible enough peptide to be released?</li></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><li>How many pores are necessary in order to be possible enough peptide to be released?</li></div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>In order to manage this, we performed data analysis and feature extraction of the existing experimentally validated datasets combined with associaton rule mining.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>In order to manage this, we performed data analysis and feature extraction of the existing experimentally validated datasets combined with associaton rule mining.</div></td></tr>
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</table>Jfkooijmanhttp://2013.igem.org/wiki/index.php?title=Team:TU-Delft/Modeling&diff=125202&oldid=prevJfkooijman at 12:22, 15 September 20132013-09-15T12:22:10Z<p></p>
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<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><h2 align="center"><del class="diffchange diffchange-inline">Band</del>-aid <del class="diffchange diffchange-inline">modeling</del></h2></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><h2 align="center"><ins class="diffchange diffchange-inline">Application modeling (band</ins>-aid<ins class="diffchange diffchange-inline">)</ins></h2></div></td></tr>
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</table>Jfkooijman