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Team:TU-Delft/Safety
From 2013.igem.org
Safety
The MRSA (Methicillin-Resistant Staphylococcus aureus) problem is our inspiration for this project. This project will focus on killing the Staphylococcus species by antimicrobial peptides synthesized in E. coli.
As we work in the lab which has only BSL-1 permit we did intense literature study to find closely related organisms of same genera other than S. aureus that can be used for our project. We used S. delphini which had some close similarities with S. aureus to test our peptides and have a prediction of their possible effect on the MRSA . The antimicrobial peptides where chosen in such a way that they have high minimum inhibitory concentration (MIC) for humans and low for S. aureus.
