Team:UI-Indonesia/Abstract

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<p><br>Tuberculosis (TB) is a worldwide major health problem which infects one third of the world’s population. The absence of reliable diagnostic tool in suburban area, where TB cases are most likely found, is still a great obstacle in TB eradication effort. Seeing Indonesia as one of the high burden countries for TB, UI-Indonesia iGEM team are trying to create a reliable, portable, and easy to use diagnostic tool for detecting TB. We are constructing a biosensor consist of highly specific antibody bound to a fragment of Beta-Galactosidase as a reporter to detect the presence of protein Ag85, a novel TB biomarker. Our goal is to make a biosensor that will detect the presence of antigen 85 in blood serum of TB suspect. Positive result will be indicated with easy to detect blue color, and when it’s negative, no response will be observed. <br></p>
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<h1>UI Student Synthetic Biology Group</h1>
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UI Indonesia iGEM team is currently trying to establish a student synthetic biology club in Universitas Indonesia, which is the first of its kind in Indonesia. The primary goal of the club itself is to increase the academic society's awareness to the importance of synthetic biology. There will be a routine meeting to discuss about the potential, safety, application and future of synthetic biology, especially in Indonesia. The group will also plan and work on a project on summer, to be finally sent as UI’s delegation for the next iGEM competition.
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The secondary goal of the club is to provide stable funding for competing in iGEM competition annually. As the first iGEM team from Universitas Indonesia, we experience difficulties in finding sponsors and donors to fund our project. Thus, UI student synthetic biology group is founded to give better direction to synthetic biology research in UI, and consequently attract sponsors and donors.
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The goal of the club itself is to provide stable funding for competing in iGEM competition annually as well as to increase the academic society's awareness to the importance of synthetic biology. We have done a small scale publication about iGEM competition to our peers and professors and the enthusiasm is greatly beyond expectation.
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We have talked to our professors and several key persons in Universitas Indonesia and we have gained their support. We also have done a small scale publication to our peers about iGEM competition and the respons is greatly beyond expectation. They would really love to work on a real research project, but they dont know where to go or where to find research funding since support for research is very scarce in Indonesia. This is where UI Student Synthetic Biology Group will play it’s role to provide lab facility and sufficient funding for research.
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We even talked to other well established team such as Paris Bettencourt team. One of Paris Bettencourt 2012 group member, miss Aishah Prastowo, is Indonesian origin. She return back to Indonesia few weeks ago and we are not missed an opportunity to talk to her about the iGEM group and iGEM competition in Paris Bettencourt. She also gives us a lot of useful advise about finding sponsors and donors as well as recruiting new candidate for the next iGEM competition.
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Revision as of 02:53, 28 September 2013

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Abstract


Tuberculosis (TB) is a worldwide major health problem which infects one third of the world’s population. The absence of reliable diagnostic tool in suburban area, where TB cases are most likely found, is still a great obstacle in TB eradication effort. Seeing Indonesia as one of the high burden countries for TB, UI-Indonesia iGEM team are trying to create a reliable, portable, and easy to use diagnostic tool for detecting TB. We are constructing a biosensor consist of highly specific antibody bound to a fragment of Beta-Galactosidase as a reporter to detect the presence of protein Ag85, a novel TB biomarker. Our goal is to make a biosensor that will detect the presence of antigen 85 in blood serum of TB suspect. Positive result will be indicated with easy to detect blue color, and when it’s negative, no response will be observed.

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