Team:TecMonterrey

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Project description
By exploiting the inherent ability of facultative anaerobic bacteria to colonize and grow in tumoral environments, this project aims to combine 3 different approaches in one bacterial system: the development of a genetically engineered Escherichia coli capable of producing two cancer specific apoptosis inducing proteins, a secretion system for the delivery of therapeutic proteins, and the design of a control mechanism confining the production of the therapeutic proteins only in tumor-specific regions.
By exploiting the inherent ability of facultative anaerobic bacteria to colonize and grow in tumoral environments, this project aims to combine 3 different approaches in one bacterial system: the development of a genetically engineered Escherichia coli capable of producing two cancer specific apoptosis inducing proteins, a secretion system for the delivery of therapeutic proteins, and the design of a control mechanism confining the production of the therapeutic proteins only in tumor-specific regions.

Revision as of 23:08, 9 August 2013

Project description

By exploiting the inherent ability of facultative anaerobic bacteria to colonize and grow in tumoral environments, this project aims to combine 3 different approaches in one bacterial system: the development of a genetically engineered Escherichia coli capable of producing two cancer specific apoptosis inducing proteins, a secretion system for the delivery of therapeutic proteins, and the design of a control mechanism confining the production of the therapeutic proteins only in tumor-specific regions.

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iGEM TecMonterrey Team
Team TecMonterrey


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