Team:Freiburg

From 2013.igem.org

Revision as of 21:43, 16 October 2013 by Ilona (Talk | contribs)


Our Team developed a universal toolkit, termed uniCAS, that enables customizable gene regulation in mammalian cells. Therefore, we engineered the recently understood and highly promising CRISPR/Cas9 system.
The regulation is based on the RNA-guided dCas9 protein, which allows targeting of specific DNA sequences. Our toolkit comprises not only a standardized dCas9 protein, but also different effector domains for efficient gene activation or repression.

All about our
project on one
page!

Use our Toolkit
to regulate your
genes!