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- | {{:Team:Goettingen/templates/header}}
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- | <html><script>
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- | </html>
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- | </div><!--close header-->
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- | </html>
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- | <html>
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- | <div class="f-box">
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- | ===Navigation:===
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- | <html>
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- | <ul class="nav">
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- | <li><a href="/Team:Goettingen/Project">Background</a></li>
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- | <li><a href="/Team:Goettingen/Project/OurProject">Our Project</a></li>
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- | <ul>
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- | <li><span style="color:#4a7ebb">Reporter Team</span></li>
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- | <li><a href="/Team:Goettingen/Team/Array">Array Team</a></li>
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- | <li><a href="/Team:Goettingen/Team/DAC">DAC Team</a></li>
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- | </ul>
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- | <li><a href="/Team:Goettingen/Parts">Registed Parts</a></li>
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- | ===Reporter Team===
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- | <img src="https://static.igem.org/mediawiki/2013/5/5a/Goe-bingyaoZhu.jpg" style="height:150px;display:inline" />
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- | <img src="https://static.igem.org/mediawiki/2013/5/5c/Goe-dominikBecker.JPG" style="height:150px;display:inline" />
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- | <img src="https://static.igem.org/mediawiki/2013/7/78/Goe-katrinTreffon.jpg" style="height:150px;display:inline" />
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- | <img src="https://static.igem.org/mediawiki/2013/e/e5/Goe-ninaHeckmann.jpg" style="height:150px;display:inline" />
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- | <img src="https://static.igem.org/mediawiki/2013/f/f1/Goe-jonathanRosenberg.jpg" style="height:150px;display:inline" />
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- | <p>The activity of transcriptional regulators can be easily monitored by expressing a reporter gene downstream of a promoter, containing their binding site. Recently, in Mycobacterium smegmatis, a transcriptional repressor (DarR) was identified that is able to bind to a specific DNA sequence upon association with c-di-AMP. This led us to the idea of developing a screening system for potential drugs interfering with c-di-AMP biofunction. While many gram-positive bacteria require c-di-AMP for their growth, this molecule is not synthesized by the gram-negative bacterium E. coli. Thus, we intend to build a reporter system consisting of the iGEM biobricks in E. coli.</p>
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- | <img src="https://static.igem.org/mediawiki/2013/6/65/Goe-reporter-1.png" style="width:40%;display:inline" />
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- | <img src="https://static.igem.org/mediawiki/2013/c/c5/Goe-reporter-2.png" style="width:40%;display:inline" />
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- | <a href="/Team:Goettingen/Project/OurProject" class="moreinfo fl"><b>Previous</b></a>
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- | <a href="/Team:Goettingen/Team/Array" class="moreinfo fr"><b>Next</b></a>
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