Team:BYU Provo/Results

Phage Library

- We were able to isolate mutant T7 bacteriophage that have a smaller average capsid size and less variability in capsid size when compared to the wild type.

- We were able to isolate mutant T4 bacteriophage that produce larger and smaller plaques, suggesting they have altered capsid size.

- We developed a cesium chloride gradient protocol for isolating larger and smaller phage.

Cholera

- We were able to show that E. coli is capable of sensing Cholera and hypothesize that it does so through its SdiA protein.

- We demonstrate induction of Lambda from lysogenic E. coli when exposed to Cholera.

- We identified a protein, Amylase A, that disrupts Cholera's biofilm formation