Team:ITB Indonesia

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<li><a href="#" data-dropdown="#dropdown-project">Project</a></li>
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<p><a href="https://2013.igem.org/Team:ITB_Indonesia/BehindTheScene/DangerAflatoxin">How Dangerous Aflatoxin for Our Bodies?</a></p>
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<p><a href="https://2013.igem.org/Team:ITB_Indonesia/BehindTheScene/AflatoxinWholeCellBiosensor">Aflatoxin Whole Cell Biosensor : Towards Indonesian Food Security</a></p>
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<p class="container-text center" id="judul">Aflatoxin Biosensor</p>
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                                    We create  a whole cell biosensor for aflatoxin B1
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                                    detection in foods.
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<h2 class="title">How Dangerous Aflatoxin for Our Bodies?</h2>
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<p class="judul">Project</p>
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Aflatoxins are carcinogenic and mutagenic, heat stable
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                                  This section is concerning our project. Including
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    (237-289&deg;C), and can accumulate through the food chain.  
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                                  project description, modelling, parts, etc.. Just
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The presence of aflatoxins especially aflatoxin B1 on 
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                                  click button below!
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food such as peanuts...
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<a href="#" class="readmore-link btn">View Details &raquo;</a>
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<a href="https://2013.igem.org/Team:ITB_Indonesia/BehindTheScene/DangerAflatoxin">Readmore</a>
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<p class="judul">Safety</p>
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                                  We ensure the safetiness of our product: Aflatoxin Biosensor.
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                                  Click here to learn more safetiness of our product.
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<h2 class="title">Aflatoxin Whole Cell Biosensor : Towards Indonesian Food Security</h2>
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<div class="entry clearfix">
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<a href="#" class="readmore-link btn">View Details &raquo;</a>
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<img src="https://static.igem.org/mediawiki/igem.org/f/f9/ITB_Indonesia-sample2.jpg" alt=""/>
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<p class="judul">Attributions</p>
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Not only for our health, Aflatoxin exposure can become
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                                  This section is concerning about what we have archived
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serious problems for economics and food security in
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                                  and of course about our generous sponsors!
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certain developing countries. Legumes is still an
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alternative staple food after rice and tubers...
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<a href="#" class="readmore-link btn">View Details &raquo;</a>
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<a href="https://2013.igem.org/Team:ITB_Indonesia/BehindTheScene/AflatoxinWholeCellBiosensor">Readmore</a>
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<h3>Aflatoxin Biosensor</h3>
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High levels of aflatoxin contamination of foods are found in many developing countries around the world. Aflatoxins are known to be mutagenic and carcinogenic, therefore human exposure to aflatoxin would lead to an increased risk of hepatocellular carcinoma (liver cancer). One in every four liver cancers in Indonesia are induced by aflatoxin B1 exposure. Nowadays, aflatoxin exposure is not only a serious problem for human health, but it could also become a serious threat in terms of food security issue of a country. ITB-Indonesia team for iGEM 2013 focuses on designing a whole cell biosensor for aflatoxin B1 detection in foods. The biosensor uses Escherichia coli as the chassis to build a genetic circuit using SOS response system to detect DNA damage caused by aflatoxin B1-oxide attack. The SOS response promoter is followed by a reporter gene coding a chromoprotein, therefore the concentration of aflatoxin B1 in food samples could be easily detected by the color change of the bacteria. For the ease of usage, we will design a syringe shaped device with our whole cell biosensor in it. This device would allow aflatoxin B1 to enter the device, but would not permit the cells to leave the device.
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<h2 class="title">Why Must be Whole Cells Biosensor ?</h2>
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<li><a href="https://igem.org/Team.cgi?year=2013&team_name=ITB_Indonesia">Official Team Profile</a></li>
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Accuracy and rapidity in monitoring toxin compounds, pollutants,
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or the presence of a pathogen in the environment became an
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important point from a measuring device (sensor). In the process
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of monitoring a toxin...
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<li><a class="fancybox" href="#inline1" title="Project Description">Project Description</a></li>
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<li><a href="https://2013.igem.org/Team:ITB_Indonesia/Modeling">Modeling</a></li>
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<a href="https://2013.igem.org/Team:ITB_Indonesia/BehindTheScene/WhyWholeCellBiosensor">Readmore</a>
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<li><a href="https://2013.igem.org/Team:ITB_Indonesia/Parts">Parts Submitted</a></li>
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<h2 class="title">Aflatoxin Whole Biosensor Safetiness</h2>
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<img src="https://static.igem.org/mediawiki/igem.org/8/80/ITB_Indonesia-Sample4.jpg" alt=""/>
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The presence  a living cell as biosensor will automatically regulate
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the introduction of a critical environmental point for a biosensor.
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So a whole cell biosensor is more prefered and more advantageous as
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biosensor device...
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</p>
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<div class="readmore">
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<a href="https://2013.igem.org/Team:ITB_Indonesia/Safety">Readmore</a>
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Latest revision as of 01:56, 28 September 2013

How Dangerous Aflatoxin for Our Bodies?

Aflatoxins are carcinogenic and mutagenic, heat stable (237-289°C), and can accumulate through the food chain. The presence of aflatoxins especially aflatoxin B1 on food such as peanuts...

Aflatoxin Whole Cell Biosensor : Towards Indonesian Food Security

Not only for our health, Aflatoxin exposure can become serious problems for economics and food security in certain developing countries. Legumes is still an alternative staple food after rice and tubers...

Why Must be Whole Cells Biosensor ?

Accuracy and rapidity in monitoring toxin compounds, pollutants, or the presence of a pathogen in the environment became an important point from a measuring device (sensor). In the process of monitoring a toxin...

Aflatoxin Whole Biosensor Safetiness

The presence a living cell as biosensor will automatically regulate the introduction of a critical environmental point for a biosensor. So a whole cell biosensor is more prefered and more advantageous as biosensor device...