Team:Braunschweig

From 2013.igem.org

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<h1>Welcome</h1>
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<h1><a href="https://2013.igem.org/Team:Braunschweig/Project/Description" class="class1">Our project</a></h1>
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<p><img alt="linie rot 8pix hoch" src="https://static.igem.org/mediawiki/2013/0/07/Team_Braunschweig_Red_line.jpg" width="400" height="1" /></p>
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<p><img alt="linie rot 8pix hoch" src="https://static.igem.org/mediawiki/2013/0/07/Team_Braunschweig_Red_line.jpg" width="405" height="1" /></p>
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<iframe width="385" height="220" src="//www.youtube.com/embed/Pk7pL_UlTX4" frameborder="0" allowfullscreen></iframe></p>
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<a href="https://2013.igem.org/Team:Braunschweig/Project/Description"><img alt="modellvereinfacht" src="https://static.igem.org/mediawiki/2013/3/37/Braunschweig_mascotts.png" width="150" align="left" vspace="15" hspace="20" alt="Text?" /></a> <p style="text-align:justify; margin-left:5px; margin-right:5px;"> <br><br>In our project we engineered a synthetic microbial consortium exploiting three different Quorum Sensing systems.</p>
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<h1>Our project</h1>
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<h1><a href="https://2013.igem.org/Team:Braunschweig/Results" class="class1">Results</a></h1>
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<p><img alt="linie rot 8pix hoch" src="https://static.igem.org/mediawiki/2013/0/07/Team_Braunschweig_Red_line.jpg" width="400" height="1" /></p>
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<p><img alt="linie rot 8pix hoch" src="https://static.igem.org/mediawiki/2013/0/07/Team_Braunschweig_Red_line.jpg" width="405" height="1" /></p>
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<img alt="modellvereinfacht" src="https://static.igem.org/mediawiki/2013/3/37/Braunschweig_mascotts.png" width="150" align="left" vspace="10" hspace="20" alt="Text?" /> <p style="text-align:justify; margin-left:5px; margin-right:5px;">Bacterial consortia offer a great benefit for synthetic biology due to the ability to perform complex tasks by splitting the whole reaction into smaller reactions and share the task among different specialized strains. Also, a self-regulating bacterial culture with intra consortial dependencies offers great advances in biosafety. To shut down the whole bacterial consortium, only on strain has to be eliminated. We engineer three different E. coli strains to grow in a consortium exploiting different Quorum Sensing systems. Each strain maintains a constitutive expression of an inactive transcription activator (LuxR, LasR or RhlR). Inducers are synthesized by different synthases (LuxI, LasI or RhlI) that are each expressed in one strain and subsequently secreted into the medium. Once taken up by a cell, the inducers bind to the corresponding, inactive transcription factors to render them functional. As a result, an antibiotic resistance under the control of an inducible promoter is expressed. </p>
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<a href="https://2013.igem.org/Team:Braunschweig/Results"><img alt="modellvereinfacht" src="https://static.igem.org/mediawiki/2013/4/40/Braunschweig_Tafel.png" width="200" height="118" align="left" vspace="35" hspace="10" alt="Text?" /></a> <p style="text-align:justify; margin-left:5px; margin-right:5px;"><br><br><br>We engineered two complementing constructs that show regulatory behavior in mixed cultures.</p>
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   <div id="leftCol"><h1>Results</h1>
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   <div id="leftCol">
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<p><img alt="linie rot 8pix hoch" src="https://static.igem.org/mediawiki/2013/0/07/Team_Braunschweig_Red_line.jpg" width="400" height="1" /></p>
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<h1><a href="https://2013.igem.org/Team:Braunschweig/Outreach" class="class1">Human Practices</a></h1>
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<img alt="modellvereinfacht" src="https://static.igem.org/mediawiki/2013/3/37/Braunschweig_mascotts.png" width="150" align="left" vspace="10" hspace="20" alt="Text?" /> <p style="text-align:justify; margin-left:5px; margin-right:5px;">In nature microorganisms commonly live in symbiosis, be it in form of a protective biofilm or as composite organism[s] such as lichen (a symbiosis of algae/cyanobacteria and fungi). Members of this symbiotic community secrete chemicals that offer protection and nutrition or neutralize toxins.
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<p><img alt="linie rot 8pix hoch" src="https://static.igem.org/mediawiki/2013/0/07/Team_Braunschweig_Red_line.jpg" width="405" height="1" /></p>
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<p style="text-align: justify; margin-left: 5px">You can find a more detailed project description <b><a href="https://2013.igem.org/Team:Braunschweig/Project/Description">here</a></b>! </p>
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<a href="https://2013.igem.org/Team:Braunschweig/Outreach"><img alt="modellvereinfacht" src="https://static.igem.org/mediawiki/2013/b/b7/Braunschweig_Guide3.png" width="120" align="left" vspace="10" hspace="20" alt="Text?" /></a> <p style="text-align:justify; margin-left:5px; margin-right:5px;"> <br><br><br>How to reach the public? We developed a guide "How to succeed in Public Relations" for all future iGEM Teams.</p>
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  <div id="rightCol"><h1>Human Practices</h1>
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<p><img alt="linie rot 8pix hoch" src="https://static.igem.org/mediawiki/2013/0/07/Team_Braunschweig_Red_line.jpg" width="400" height="1" /></p>
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<h1>Get to know Eric Collins</h1>
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<img alt="modellvereinfacht" src="https://static.igem.org/mediawiki/2013/b/b7/Braunschweig_Guide3.png" width="120" align="left" vspace="10" hspace="20" alt="Text?" /> <p style="text-align:justify; margin-left:5px; margin-right:5px;"><br><br><br>How to reach the public? We developed a guide "How to succeed in Public Relations" for all future iGEM Teams.</p>
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<p><img alt="linie rot 8pix hoch" src="https://static.igem.org/mediawiki/2013/0/07/Team_Braunschweig_Red_line.jpg" width="405" height="1" /></p>
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<p><br><iframe width="330" height="200" src="//www.youtube.com/embed/Pk7pL_UlTX4" frameborder="0" allowfullscreen></iframe></p>
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   <div id="leftCol"><h1>Engineering Principles</h1>
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   <div id="leftCol">
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<p><img alt="linie rot 8pix hoch" src="https://static.igem.org/mediawiki/2013/0/07/Team_Braunschweig_Red_line.jpg" width="400" height="1" /></p>
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<h1><a href="https://2013.igem.org/Team:Braunschweig/Project/Impact" class="class1">Impact</a></h1>
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<img alt="modellvereinfacht" src="https://static.igem.org/mediawiki/2013/6/69/Braunschweig_EngineeringPrinciples.png" width="150" align="left" vspace="10" hspace="20" alt="Text?" /> <p style="text-align:justify; margin-left:5px; margin-right:5px;">In nature microorganisms commonly live in symbiosis, be it in form of a protective biofilm or as composite organism[s] such as lichen (a symbiosis of algae/cyanobacteria and fungi). Members of this symbiotic community secrete chemicals that offer protection and nutrition or neutralize toxins.
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<p><img alt="linie rot 8pix hoch" src="https://static.igem.org/mediawiki/2013/0/07/Team_Braunschweig_Red_line.jpg" width="405" height="1" /></p>
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<p style="text-align: justify; margin-left: 5px">You can find a more detailed project description <b><a  href="https://2013.igem.org/Team:Braunschweig/Project/Description">here</a></b>! </p>
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<a href="https://2013.igem.org/Team:Braunschweig/Project/Impact"><img alt="modellvereinfacht" src="https://static.igem.org/mediawiki/2013/d/df/Braunschweig_Dominos.jpg" width="150" align="left" vspace="10" hspace="20" alt="Text?" /></a> <p style="text-align:justify; margin-left:5px; margin-right:5px;" <br><br><br>With our engineered microbial consortium we contribute to the establishment of a universal and widely applicable system.</p>
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   <div id="rightCol"><h1>Impact</h1>
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   <div id="rightCol">
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<p><img alt="linie rot 8pix hoch" src="https://static.igem.org/mediawiki/2013/0/07/Team_Braunschweig_Red_line.jpg" width="400" height="1" /></p>
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<h1><a href="https://2013.igem.org/Team:Braunschweig/Project/Engineering_Principles" class="class1">Engineering Principles</a></h1>
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<img alt="modellvereinfacht" src="https://static.igem.org/mediawiki/2013/3/37/Braunschweig_mascotts.png" width="150" align="left" vspace="10" hspace="20" alt="Text?" /> <p style="text-align:justify; margin-left:5px; margin-right:5px;">In nature microorganisms commonly live in symbiosis, be it in form of a protective biofilm or as composite organism[s] such as lichen (a symbiosis of algae/cyanobacteria and fungi). Members of this symbiotic community secrete chemicals that offer protection and nutrition or neutralize toxins.
+
<p><img alt="linie rot 8pix hoch" src="https://static.igem.org/mediawiki/2013/0/07/Team_Braunschweig_Red_line.jpg" width="405" height="1" /></p>
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<p style="text-align: justify; margin-left: 5px">You can find a more detailed project description <b><a  href="https://2013.igem.org/Team:Braunschweig/Project/Description">here</a></b>! </p>
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<a href="https://2013.igem.org/Team:Braunschweig/Project/Engineering_Principles"><img alt="modellvereinfacht" src="https://static.igem.org/mediawiki/2013/6/69/Braunschweig_EngineeringPrinciples.png" width="140" align="left" vspace="10" hspace="20" alt="Text?" /></a> <p style="text-align:justify; margin-left:5px; margin-right:5px;"><br>Our devices were assembled in a modular manner out of individual operation units. The design with distinct operation units guarantees high flexibility during assembly of the final construct.</p>
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<h1>Our sponsors</h1>
<h1>Our sponsors</h1>
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<p><img alt="linie rot 8pix hoch" src="https://static.igem.org/mediawiki/2013/0/07/Team_Braunschweig_Red_line.jpg" width="850" height="1" margin-bottom:"2"/></p>
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<p><img alt="linie rot 8pix hoch" src="https://static.igem.org/mediawiki/2013/0/07/Team_Braunschweig_Red_line.jpg" width="890" height="1" margin-bottom:"2"/></p>
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Latest revision as of 14:31, 27 October 2013

Our project

linie rot 8pix hoch

modellvereinfacht



In our project we engineered a synthetic microbial consortium exploiting three different Quorum Sensing systems.

Results

linie rot 8pix hoch

modellvereinfacht




We engineered two complementing constructs that show regulatory behavior in mixed cultures.

Human Practices

linie rot 8pix hoch

modellvereinfacht




How to reach the public? We developed a guide "How to succeed in Public Relations" for all future iGEM Teams.

Get to know Eric Collins

linie rot 8pix hoch


Impact

linie rot 8pix hoch

modellvereinfacht



With our engineered microbial consortium we contribute to the establishment of a universal and widely applicable system.

Engineering Principles

linie rot 8pix hoch

modellvereinfacht


Our devices were assembled in a modular manner out of individual operation units. The design with distinct operation units guarantees high flexibility during assembly of the final construct.

Our sponsors

linie rot 8pix hoch

Retrieved from "http://2013.igem.org/Team:Braunschweig"