Team:Braunschweig

From 2013.igem.org

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<strong>What iGEM is about</strong></p>
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<a href="https://2013.igem.org/Main_Page" target="_blank">iGEM</a> (International Genetically Engineered Machine Competition) is an international competition in the field of Synthetic Biology organized by the Massachusetts Institute of Technology (MIT) in Boston. It is an annually occurring event, designed for undergraduate students and as of late also high school students and entrepreneurs. It encourages teams to develop novel, creative and inspiring ideas for the use of genetically engineered systems to solve social and scientific problems. Next year, the event celebrates its 10th anniversary.</p>
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<em>iGEM foundation </em><br />
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The iGEM competition is hosted by the iGEM foundation, an independent and non-profit organization originating from <em>BioBricks </em><br />
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<h1><a href="https://2013.igem.org/Team:Braunschweig/Project/Description" class="class1">Our project</a></h1>
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Participating teams are equipped with a kind of gene-kit. The so called “BioBricks” can be combined freely for the projects. As a part of the iGEM concept, teams are also encouraged to improve already existing bricks or develop new bricks to add them to the database for usage in future projects.</p>
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<p><img alt="linie rot 8pix hoch" src="https://static.igem.org/mediawiki/2013/0/07/Team_Braunschweig_Red_line.jpg" width="405" height="1" /></p>
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<em>Aim </em><br />
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<a href="https://2013.igem.org/Team:Braunschweig/Project/Description"><img alt="modellvereinfacht" src="https://static.igem.org/mediawiki/2013/3/37/Braunschweig_mascotts.png" width="150" align="left" vspace="15" hspace="20" alt="Text?" /></a> <p style="text-align:justify; margin-left:5px; margin-right:5px;"> <br><br>In our project we engineered a synthetic microbial consortium exploiting three different Quorum Sensing systems.</p>
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The iGEM competition is dedicated to promote teamwork, scientific research and advancement of Synthetic Biology.</p>
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<img alt="linie rot 8pix hoch" src="http://en.igem-braunschweig.de/wp-content/uploads/2013/04/linie-rot-8pix-hoch.jpg" width="700" height="1" /></p>
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<strong>Our project &#8211; outline</strong></p>
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In nature microorganisms commonly live in symbiosis, be it in form of a protective biofilm or as composite organism[s] such as lichen (a symbiosis of algae/cyanobacteria and fungi). Members of this symbiotic community secrete chemicals that offer protection and nutrition or neutralize toxins.
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<a href="http://de.igem-braunschweig.de/wp-content/uploads/2013/04/Modell-vereinfacht.png"><img class="alignright" alt="Modell vereinfacht" src="http://de.igem-braunschweig.de/wp-content/uploads/2013/04/Modell-vereinfacht-279x300.png" width="279" height="300"/></a>The goal of the iGEM Team Braunschweig is to create a synergetic system similar to a natural symbiosis. During the course of our project we want to clone three individual mutant strains of the bacterium <em>Escherichia coli</em> which can only survive as a community – if one dies, they all die.<br />
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To achieve this, each strain bears a plasmid that confers antibiotic resistance upon activation of a two-component transcription activator.<br />
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The key feature of our system: only one component can be synthesized by each strain alone. The other half of a transcription activator is produced by another strain and secreted into the medium.</p>
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<p style="text-align: justify;">Curious? <a href="http://en.igem-braunschweig.de/project-2/our-project/">Here</a> you can find more details.</p>
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<p style="text-align: justify;"><img alt="linie rot 8pix hoch" src="http://en.igem-braunschweig.de/wp-content/uploads/2013/04/linie-rot-8pix-hoch.jpg" width="700" height="1" /></p>
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<h1><a href="https://2013.igem.org/Team:Braunschweig/Results" class="class1">Results</a></h1>
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<p><img alt="linie rot 8pix hoch" src="https://static.igem.org/mediawiki/2013/0/07/Team_Braunschweig_Red_line.jpg" width="405" height="1" /></p>
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<a href="https://2013.igem.org/Team:Braunschweig/Results"><img alt="modellvereinfacht" src="https://static.igem.org/mediawiki/2013/4/40/Braunschweig_Tafel.png" width="200" height="118" align="left" vspace="35" hspace="10" alt="Text?" /></a> <p style="text-align:justify; margin-left:5px; margin-right:5px;"><br><br><br>We engineered two complementing constructs that show regulatory behavior in mixed cultures.</p>
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<h1><a href="https://2013.igem.org/Team:Braunschweig/Outreach" class="class1">Human Practices</a></h1>
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<p><img alt="linie rot 8pix hoch" src="https://static.igem.org/mediawiki/2013/0/07/Team_Braunschweig_Red_line.jpg" width="405" height="1" /></p>
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<a href="https://2013.igem.org/Team:Braunschweig/Outreach"><img alt="modellvereinfacht" src="https://static.igem.org/mediawiki/2013/b/b7/Braunschweig_Guide3.png" width="120" align="left" vspace="10" hspace="20" alt="Text?" /></a> <p style="text-align:justify; margin-left:5px; margin-right:5px;"> <br><br><br>How to reach the public? We developed a guide "How to succeed in Public Relations" for all future iGEM Teams.</p>
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<h1>Get to know Eric Collins</h1>
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<p><img alt="linie rot 8pix hoch" src="https://static.igem.org/mediawiki/2013/0/07/Team_Braunschweig_Red_line.jpg" width="405" height="1" /></p>
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<p><br><iframe width="330" height="200" src="//www.youtube.com/embed/Pk7pL_UlTX4" frameborder="0" allowfullscreen></iframe></p>
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<h1><a href="https://2013.igem.org/Team:Braunschweig/Project/Impact" class="class1">Impact</a></h1>
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<p><img alt="linie rot 8pix hoch" src="https://static.igem.org/mediawiki/2013/0/07/Team_Braunschweig_Red_line.jpg" width="405" height="1" /></p>
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<a href="https://2013.igem.org/Team:Braunschweig/Project/Impact"><img alt="modellvereinfacht" src="https://static.igem.org/mediawiki/2013/d/df/Braunschweig_Dominos.jpg" width="150" align="left" vspace="10" hspace="20" alt="Text?" /></a> <p style="text-align:justify; margin-left:5px; margin-right:5px;" <br><br><br>With our engineered microbial consortium we contribute to the establishment of a universal and widely applicable system.</p>
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<h1><a href="https://2013.igem.org/Team:Braunschweig/Project/Engineering_Principles" class="class1">Engineering Principles</a></h1>
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<p><img alt="linie rot 8pix hoch" src="https://static.igem.org/mediawiki/2013/0/07/Team_Braunschweig_Red_line.jpg" width="405" height="1" /></p>
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<a href="https://2013.igem.org/Team:Braunschweig/Project/Engineering_Principles"><img alt="modellvereinfacht" src="https://static.igem.org/mediawiki/2013/6/69/Braunschweig_EngineeringPrinciples.png" width="140" align="left" vspace="10" hspace="20" alt="Text?" /></a> <p style="text-align:justify; margin-left:5px; margin-right:5px;"><br>Our devices were assembled in a modular manner out of individual operation units. The design with distinct operation units guarantees high flexibility during assembly of the final construct.</p>
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<h1>Our sponsors</h1>
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<p><img alt="linie rot 8pix hoch" src="https://static.igem.org/mediawiki/2013/0/07/Team_Braunschweig_Red_line.jpg" width="890" height="1" margin-bottom:"2"/></p>
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<img src="https://static.igem.org/mediawiki/2013/9/9e/SponsorenBS.png" width="850px" /></p>
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Latest revision as of 14:31, 27 October 2013

Our project

linie rot 8pix hoch

modellvereinfacht



In our project we engineered a synthetic microbial consortium exploiting three different Quorum Sensing systems.

Results

linie rot 8pix hoch

modellvereinfacht




We engineered two complementing constructs that show regulatory behavior in mixed cultures.

Human Practices

linie rot 8pix hoch

modellvereinfacht




How to reach the public? We developed a guide "How to succeed in Public Relations" for all future iGEM Teams.

Get to know Eric Collins

linie rot 8pix hoch


Impact

linie rot 8pix hoch

modellvereinfacht



With our engineered microbial consortium we contribute to the establishment of a universal and widely applicable system.

Engineering Principles

linie rot 8pix hoch

modellvereinfacht


Our devices were assembled in a modular manner out of individual operation units. The design with distinct operation units guarantees high flexibility during assembly of the final construct.

Our sponsors

linie rot 8pix hoch