Team:UIUC Illinois

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You are provided with this team page template with which to start the iGEM season. You may choose to personalize it to fit your team but keep the same "look." Or you may choose to take your team wiki to a different level and design your own wiki. You can find some examples <a href="https://2009.igem.org/Help:Template/Examples">HERE</a>.
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    <a href="https://2013.igem.org/Team:_UIUC_Illinois/Contact_Us" class="right"><u>Contact Us</u></a>
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        <a href="https://2013.igem.org/Team:UIUC_Illinois"><img src="https://static.igem.org/mediawiki/2013/0/02/Illinoisigem.png" width="407.36" height="200" alt="UIUC iGEM" class="center" /></a>
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Our project, Cardiobiotics, works to prevent cardiovascular disease by reducing the metabolism of dietary L-carnitine within the digestive system.  This made possible through the use of three biological parts that fulfill two very important functions: the take-up and the break-down of L-carnitine.<br><br>
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The take-up of L-carnitine into the cell is facilitated by two biobricks: the <a href="http://parts.igem.org/Part:BBa_K1205002">CbcWV Uptake Protein</a> and <a href="http://parts.igem.org/Part:BBa_K1205001">CaiX Carnitine Carrier Protein</a>.  This combination of proteins form a membrane-bound carnitine uptake system for bringing greater amounts of L-carnitine into the cell.<br><br>
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The break-down of L-carnitine is carried out by our biobrick <a href="http://parts.igem.org/Part:BBa_K1205000">Carnitine Dehydrogenase</a>.  This protein catalyzes the conversion of L-carnitine into 3-dehydrocarnitine, pushing it down an alternative metabolic pathway towaord the creation of the amino acid glycine.<br><br>
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The cells containing the biological parts are then suspended within calcium alginate and inserted into gelatin capsules in order to transport them to the intestinal system.
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  <h3>About</h3>
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  <h3>Project</h3>
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      <li style="margin-bottom:20px;"><a href="https://2013.igem.org/Team:UIUC_Illinois/Project/Overview">Overview</a></li>
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      <li style="margin-bottom:20px;"><a href="https://2013.igem.org/Team:_UIUC_Illinois/Notebook">Notebook</a></li>
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  <h3>Achievements</h3>
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  <ul>
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      <li style="margin-bottom:20px;"><a href="https://2013.igem.org/Team_UIUC_Illinois/Medal_Requirements">Achievements</a></li>
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  <h3>Human Practices</h3>
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  <h3>Safety</h3>
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      <li style="margin-bottom:20px;"><a href="https://igem.org/Team:UIUC_Illinois/Safety/Main">Safety Main Page</a></li>
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<h3>Thanks to our sponsors!</h3></div>
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<div id="sponsor_innerbox"><a href="http://bioengineering.illinois.edu"><img src="https://static.igem.org/mediawiki/2013/e/e8/Bioedept.jpg" width="299" height="40"></a></div>
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|[[Image:UIUC_Illinois_logo.png|200px|right|frame]]
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|align="center"|[[Team:UIUC_Illinois | Team UIUC_Illinois]]
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!align="center"|[[Team:UIUC_Illinois|Home]]
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!align="center"|[[Team:UIUC_Illinois/Notebook|Notebook]]
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Latest revision as of 23:40, 19 February 2014

Contact Us
UIUC iGEM
Smiling fox
Our project, Cardiobiotics, works to prevent cardiovascular disease by reducing the metabolism of dietary L-carnitine within the digestive system. This made possible through the use of three biological parts that fulfill two very important functions: the take-up and the break-down of L-carnitine.

The take-up of L-carnitine into the cell is facilitated by two biobricks: the CbcWV Uptake Protein and CaiX Carnitine Carrier Protein. This combination of proteins form a membrane-bound carnitine uptake system for bringing greater amounts of L-carnitine into the cell.

The break-down of L-carnitine is carried out by our biobrick Carnitine Dehydrogenase. This protein catalyzes the conversion of L-carnitine into 3-dehydrocarnitine, pushing it down an alternative metabolic pathway towaord the creation of the amino acid glycine.

The cells containing the biological parts are then suspended within calcium alginate and inserted into gelatin capsules in order to transport them to the intestinal system.

Retrieved from "http://2013.igem.org/Team:UIUC_Illinois"