Team:EPF Lausanne

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<br><br><br>
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We are proud to participate in iGEM 2013 and are excited to present<br>
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'''Taxi.Coli'''.
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<br>
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Taxi.Coli is a highly flexible and adaptable smart drug delivery system.<br>
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We want to use E.coli as a ''Taxi'', that expresses streptavidin on its surface as ''Seats'' for the ''Passengers'', which are the biotinylated nanoparticles that contain a drug. Once Taxi.Coli arrives at ''the Address'', a specific environment, it will produce an enzyme that degrades the nanoparticles, releasing the incorporated drug ''the passenger gets out of the car''. <br>Our effort will be limited to a proof of principle, but one can imagine a wide range of future applications.
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You are provided with this team page template with which to start the iGEM season.  You may choose to personalize it to fit your team but keep the same "look." Or you may choose to take your team wiki to a different level and design your own wiki.  You can find some examples <a href="https://2009.igem.org/Help:Template/Examples">HERE</a>.
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<a class="twitter-timeline" data-dnt="true" href="https://twitter.com/iGEM_EPFL" data-widget-id="246305483747631104">Tweets by @iGEM_EPFL</a>
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|You can write a background of your team here. Give us a background of your team, the members, etc. Or tell us more about something of your choosing.
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==Achievements:==
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- We can produce biotinylated nanoparticles<br>
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- We can engineer E.coli expressing streptavidin (maybe even on the surface) to bind these nanoparticles<br>
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''Tell us more about your project. Give us background. Use this as the abstract of your project. Be descriptive but concise (1-2 paragraphs)''
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- We can engineer E.coli to sense different values of pH<br>
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|[[Image:EPF_Lausanne_team.png|right|frame|Your team picture]]
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- We can make E.coli express superfolded GFP constitutively<br>
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- We can excite other students about synthetic biology<br>
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|align="center"|[[Team:EPF_Lausanne | Team EPF_Lausanne]]
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Please also visit our [https://www.facebook.com/groups/EPFL.IGEM2013/ Facebook page]!
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<h2>Medal requirements</h2>
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<h3>Bronze medal</h3>
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<ul class="checkmark-list">
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  <li>We registered the team and had fun in the competition.</li>
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  <li>We filled in the Judging form.</li>
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  <li>We described our project using the iGEM wiki and our parts using the Registry of Standard Biological Parts.</li>
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  <li>We plan to present a poster and talk at the iGEM Jamboree in Lyon.</li>
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  <li>We designed and submitted the following Biobricks BBa_K1111001, BBa_K1111002, BBa_K111103, BBa_K1111004, BBa_K1111005, BBa_K1111006, BBa_K1111007, BBa_K1111008, BBa_K1111009, BBa_K1111010, BBa_K1111011, BBa_K1111012, BBa_K1111013, BBa_K1111014.</li>
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<h3>Silver medal</h3>
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  <li>We experimentally validated that the Biobrick BBa_K1111005 works as expected.</li>
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  <li>We documented all our parts on the iGEM Registry of Standard Biological Parts.</li>
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  <li>We investigated the safety issues which could be raised by our project. Take a look at our safety page.</li>
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<h3>Gold medal</h3>
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<ul class="checkmark-list">
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  <li>We improved the function of the already existing Biobrick BBa_K523013 by extensively characterizing and documenting it. This will help future teams to use it.</li>
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  <li>We prepared an amazing synthetic biology kit which will be used at public events and high school visits at EPFL. Take a look at our Outreach page. </li>
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<li>We organized a women and engineering's day at our university to promote women in science. </li>
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<br><br>
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<h3>European Jamboree Results</h3>
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<ul class="checkmark-list">
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  <li>SILVER MEDAL</li>
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  <li>ADVANCE  TO WORLD CHAMPIONSHIP</li>
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<!--- The Mission, Experiments --->
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== Thanks to our sponsors ==
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Many thanks to our sponsors who made it possible for us to take part in this amazing competition.
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<br>
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[[File:Team-EPF-Lausanne sponso.jpg|center|550px]]
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!align="center"|[[Team:EPF_Lausanne/Team|Team]]
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!align="center"|[https://igem.org/Team.cgi?year=2013&team_name=EPF_Lausanne Official Team Profile]
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!align="center"|[[Team:EPF_Lausanne/Project|Project]]
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!align="center"|[[Team:EPF_Lausanne/Parts|Parts Submitted to the Registry]]
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Latest revision as of 00:06, 29 October 2013

Taxi.Coli: Smart Drug Delivery iGEM EPFL

Header




We are proud to participate in iGEM 2013 and are excited to present
Taxi.Coli.
Taxi.Coli is a highly flexible and adaptable smart drug delivery system.
We want to use E.coli as a Taxi, that expresses streptavidin on its surface as Seats for the Passengers, which are the biotinylated nanoparticles that contain a drug. Once Taxi.Coli arrives at the Address, a specific environment, it will produce an enzyme that degrades the nanoparticles, releasing the incorporated drug the passenger gets out of the car.
Our effort will be limited to a proof of principle, but one can imagine a wide range of future applications.





Project
Team
Safety
Outreach





Achievements:

- We can produce biotinylated nanoparticles
- We can engineer E.coli expressing streptavidin (maybe even on the surface) to bind these nanoparticles
- We can engineer E.coli to sense different values of pH
- We can make E.coli express superfolded GFP constitutively
- We can excite other students about synthetic biology



Please also visit our Facebook page!


Medal requirements

Bronze medal

  • We registered the team and had fun in the competition.
  • We filled in the Judging form.
  • We described our project using the iGEM wiki and our parts using the Registry of Standard Biological Parts.
  • We plan to present a poster and talk at the iGEM Jamboree in Lyon.
  • We designed and submitted the following Biobricks BBa_K1111001, BBa_K1111002, BBa_K111103, BBa_K1111004, BBa_K1111005, BBa_K1111006, BBa_K1111007, BBa_K1111008, BBa_K1111009, BBa_K1111010, BBa_K1111011, BBa_K1111012, BBa_K1111013, BBa_K1111014.

Silver medal

  • We experimentally validated that the Biobrick BBa_K1111005 works as expected.
  • We documented all our parts on the iGEM Registry of Standard Biological Parts.
  • We investigated the safety issues which could be raised by our project. Take a look at our safety page.

Gold medal

  • We improved the function of the already existing Biobrick BBa_K523013 by extensively characterizing and documenting it. This will help future teams to use it.
  • We prepared an amazing synthetic biology kit which will be used at public events and high school visits at EPFL. Take a look at our Outreach page.
  • We organized a women and engineering's day at our university to promote women in science.


    • European Jamboree Results

    • SILVER MEDAL
    • ADVANCE TO WORLD CHAMPIONSHIP



    Thanks to our sponsors

    Many thanks to our sponsors who made it possible for us to take part in this amazing competition.

    Team-EPF-Lausanne sponso.jpg



Wiki Links

Retrieved from "http://2013.igem.org/Team:EPF_Lausanne"