Team:TU Darmstadt/Modeling

From 2013.igem.org

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<a href="https://2013.igem.org/Team:TU_Darmstadt/Modelling/Statistics" >
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Mycotoxins produced by mould fungus are present in our daily life and are harmful for humans as well as for animals.
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The danger of contamination of gain and other natural products has fatal consequences for the economy and the supply of whole nations.  
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The mycotoxins which are permanently formed by the fungus, can be used as biomarkers to detect contamination.
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<font size="6" color="#F0F8FF" face="Arial regular">Satistics</font>
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We want to develop a handy device which allows an easy and reliable detection of mycotoxins.
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To achieve this goal our team uses various methods from the fields of synthetic biology,
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electrical engineering and information processing. The detection system relies on <i>E.coli</i>  
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with modified aspartate receptors (TAR) which interact with specific mycotoxins.
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If these are present in the reviewed sample they will bind to the receptor and induce
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a conformational change and thereby generates a measurable FRET-beacon by bringing
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two flourophores in close distance to each other.
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The modified <i>E.coli</i> will be embedded in interchangeable capsules. Together with a handheld-device
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they will guarantee that measurements can be done quickly, easy to operate and secure.
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The data will be transferred from the handheld system to an Android smartphone app which will be
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able to analyze, illustrate and store the test results for the user.
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Revision as of 14:45, 1 October 2013