Team:Arizona State/Adjuvants

From 2013.igem.org

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<h3>CpG Motifs</h3>
<h3>CpG Motifs</h3>
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Synthetic CpG Oligodeoxynucleotides are short single-stranded synthetic DNA molecules that contain a cytosine triphosphate deoxynucleotide ("C)" followed by a guanine triphosphate deoxynucleotide ("G"). Because they are unmethylated, they act as immunostimulants. Because bacterial chassis contain a large number of unmethylated CG motifs in their genome, they provide a strong natural immunostimulant in parallel with antigen delivery.
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Revision as of 23:38, 27 September 2013

GMCSF recruits Immune Cells to Site of Infection

CpG Motifs

Synthetic CpG Oligodeoxynucleotides are short single-stranded synthetic DNA molecules that contain a cytosine triphosphate deoxynucleotide ("C)" followed by a guanine triphosphate deoxynucleotide ("G"). Because they are unmethylated, they act as immunostimulants. Because bacterial chassis contain a large number of unmethylated CG motifs in their genome, they provide a strong natural immunostimulant in parallel with antigen delivery.