Team:Cornell/project/future/bioremediation

upregulation of these metal chelating pathways and biosensing genetic circuits could feasibly be integrated into a basidiomycete strain, decreasing pollution whilst monitoring and reporting pollution levels. In addition, fungal mycelium can form dense masses (like Ecovative’s biomaterial) that can slow the flow of water and act as a solids filter. Such filters could act as permanent bioswales or buffers around water bodies, decreasing runoff pollution from agricultural and industrial areas. A safe filter could also be developed for human use. Such a filter would be reusable and inexpensive, providing clean water to those in impoverished areas. Our toolkit would be vital to the development of these products. To reproduce, fungi release spores that (depending on the species) could be harmful if inhaled. To produce a fungal material safe for food or water containment, sporulation would have to be regulated. Sporulation in basidiomycetes is regulated by the highly conserved velvet protein group [2]. Our toolkit could be utilized to silence these genes and create a safe fungal product.