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We are proud to participate in IGEM 2013 and are excited to present
Taxi.Coli - smart drug delivery

The basic idea is quite simple:
We will use E.coli as a "Taxi", add streptavidin to the surface as "Seats" and nanoparticles incorporating drugs as the "Passengers". The "Taxi" will recognize the right "Adress" with a pH sensor and the "Passengers" gets out.

Achievements:

- we can produce biotynilated nanoparticles
- we can engineer E.coli expressing streptavidin (maybe even on the surface) to bind these nanoparticles
- we can engineer E.coli to sense different levels of pH

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Medal requirements

Bronze medal

• Register the team, have fun in the competition.
• iGEM 2013 Judging form.
• Description of the team's project using the iGEM wiki and the team's parts using the Registry of Standard Biological Parts.
• Present a poster and talk at the iGEM Jamboree.
• Document at least one new standard BioBrick Part and submit it to the Registry + a new application and documentation of a previously existing BioBrick part in the Registry

Silver medal

• Experimentally validate that at least one new BioBrick Part of your own design and construction works as expected.
• Document the characterization of this part and submit this new part to the iGEM Parts Registry
• Implications for the environment, security, safety and ethics and/or ownership and sharing. Describe one or more ways in which these or other broader implications have been taken into consideration in the design and execution of your project.

Gold medal

• Improve the function of an existing BioBrick Part or Device
• Outline and detail a new approach to an issue of Human Practice in synthetic biology as it relates to your project, such as safety, security, ethics, or ownership, sharing, and innovation.


Figure1: Many thank to our sponsor: AC IMMUNE
File:Team-EPF-Lausanne-sponsor4.jpeg
Figure1: Many thank to our sponsor: EPFL