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We are proud to participate in IGEM 2013 and are excited to present
Taxi.Coli - smart drug delivery

The basic idea is simple:
We will use E.coli as a "Taxi", add streptavidin to the surface as "Seats" and nanoparticles incorporating drugs as the "Passengers". The "Taxi" will recognize the right "Adress" with a pH sensor and the "Passengers" gets released by an enzyme.

Achievements:

- we can produce biotynilated nanoparticles
- we can engineer E.coli expressing streptavidin (maybe even on the surface) to bind these nanoparticles
- we can engineer E.coli to sense different levels of pH

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Medal requirements

Bronze medal

Register the team, have fun in the competition.
iGEM 2013 Judging form.
Description of the team's project using the iGEM wiki and the team's parts using the Registry of Standard Biological Parts.
Plan to present a poster and talk at the iGEM Jamboree.
Document at least one new standard BioBrick Part and submit it to the Registry + a new application and documentation of a previously existing BioBrick part in the Registry
We sent the following Biobricks:
BBa_K1111002, BBa_K1111004, BBa_K1111005, BBa_K1111007, BBa_K1111009, BBa_K1111012, BBa_K1111013, BBa_K1111014.

Silver medal

Experimentally validate that at least one new BioBrick Part of your own design and construction works as expected. BBa_K1111005
Document the characterization of this part and submit this new part to the iGEM Parts Registry
Implications for the environment, security, safety and ethics and/or ownership and sharing. Describe one or more ways in which these or other broader implications have been taken into consideration in the design and execution of your project. Take a look at our safety page.

Gold medal

Improve the function of an existing BioBrick Part or Device
We documented and characterized the already existing Biobrick BBa_K523013 extensively
Outline and detail a new approach to an issue of Human Practice in synthetic biology as it relates to your project, such as safety, security, ethics, or ownership, sharing, and innovation. Take a look at our Outreach page.