Team:Cornell/project/wetlab/fungal toolkit/homologous constructs
From 2013.igem.org
Homologous Constructs
Background
Eukaryotic cells can incorporate foreign DNA through random insertion and homologous recombination. In random insertion, foreign DNA is randomly integrated into the genome through a process that is currently not well understood. Homologous recombination is the process by which DNA is exchanged between a genome and a construct in regions of homology. Thus, we can place a gene of interest between known regions of homology in order to increase its chances of being incorporated into the genome. This process has been noted to be especially effective in transforming plant and fungal species.![](https://static.igem.org/mediawiki/2013/c/c2/Homologous_recom.png)