Team:EPF Lausanne

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'''Taxi.Coli: smart drug delivery'''
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Researchers all over the world strive to improve the effectiveness of drugs. Emergent strategies such as "Targeted drug delivery" allow a more precise and localized administration of drugs. The aim of this method is to increase drug concentration in a specific location (e.g. a tumor); yet decreasing secondary effects on healthy tissues. This method reduces the frequency and dose of drug administration.  
Researchers all over the world strive to improve the effectiveness of drugs. Emergent strategies such as "Targeted drug delivery" allow a more precise and localized administration of drugs. The aim of this method is to increase drug concentration in a specific location (e.g. a tumor); yet decreasing secondary effects on healthy tissues. This method reduces the frequency and dose of drug administration.  

Revision as of 16:33, 19 September 2013

Taxi.Coli: Smart Drug Delivery iGEM EPFL

Header

Taxi.Coli: smart drug delivery

Researchers all over the world strive to improve the effectiveness of drugs. Emergent strategies such as "Targeted drug delivery" allow a more precise and localized administration of drugs. The aim of this method is to increase drug concentration in a specific location (e.g. a tumor); yet decreasing secondary effects on healthy tissues. This method reduces the frequency and dose of drug administration.

EPFL team’s goal this year is to suggest a drug delivery strategy. The key word of this project is “adaptability”. Our motivation is to explore a way of using E.Coli as a drug carrier in a way that is highly modular; thereby suiting several applications and possibilities of disease treatment.

Using the principles of synthetic biology we will bond nanoparticles containing a drug to E.coli using the biotin-streptavidin interaction. The engineered E.coli will target the site where the drug is required. Upon stimuli it starts to release a protease degrading the nanoparticles and hence delivers the drug.


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Bacteria

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Nizza Strand


You can write a background of your team here. Give us a background of your team, the members, etc. Or tell us more about something of your choosing.
EPFL LOG RVB-96.tiff

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Team EPF_Lausanne

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