Team:EPF Lausanne

From 2013.igem.org

(Difference between revisions)
Line 17: Line 17:
Taxi.Coli: smart drug delivery
Taxi.Coli: smart drug delivery
-
EPF_Lausanne’s team is proud to participate to iGEM 2013 and excited to present their project:
 
-
Taxi.Coli: smart drug delivery.
 
-
The team’s vision is to build a biosynthetic drug delivery concept.  
+
EPF_Lausanne’s team is proud to participate to iGEM 2013 and excited to present their project: Taxi.Coli: smart drug delivery. The team’s vision is to build a biosynthetic drug delivery concept. The key word of this project is “adaptability”. Our goal is to explore a way of using E.Coli as a highly modular carrier, opening the gate to several applications and alternatives in disease treatments. Using the principles of synthetic biology, we engineered a gelatinase secreting E. Coli able to bind gelatin nanoparticles using a biotin-streptavidin interaction and release them in a corresponding location. The drug delivery system is built in three parts: 1) the nanoparticle binding and 2) the environment sensing that 3) triggers the gelatinase release of the engineered E. Coli, liberating the content of the nanoparticle. The nanoparticles made of gelatin are able to carry any type of organic compound leading to a wide range of applications.
-
The key word of this project is “adaptability”. Our goal is to explore a way of using E.Coli as a highly  
+
-
modular carrier, opening the gate to several applications and alternatives in disease treatments.  
+
-
 
+
-
Using the principles of synthetic biology, we engineered a gelatinase secreting E. Coli able to bind
+
-
gelatin nanoparticles using a biotin-streptavidin interaction and release them in a corresponding location.  
+
-
The drug delivery system is built in three parts: 1) the nanoparticle binding and 2) the environment sensing  
+
-
that 3) triggers the gelatinase release of the engineered E. Coli, liberating the content of the nanoparticle.  
+
-
 
+
-
The nanoparticles made of gelatin are able to carry any type of organic compound leading to a wide range  
+
-
of applications.
+
{{Template:EPFL2013Footer}}
{{Template:EPFL2013Footer}}

Revision as of 20:07, 26 September 2013

Taxi.Coli: Smart Drug Delivery iGEM EPFL

Header

Taxi.Coli: smart drug delivery

Taxi.Coli: smart drug delivery

EPF_Lausanne’s team is proud to participate to iGEM 2013 and excited to present their project: Taxi.Coli: smart drug delivery. The team’s vision is to build a biosynthetic drug delivery concept. The key word of this project is “adaptability”. Our goal is to explore a way of using E.Coli as a highly modular carrier, opening the gate to several applications and alternatives in disease treatments. Using the principles of synthetic biology, we engineered a gelatinase secreting E. Coli able to bind gelatin nanoparticles using a biotin-streptavidin interaction and release them in a corresponding location. The drug delivery system is built in three parts: 1) the nanoparticle binding and 2) the environment sensing that 3) triggers the gelatinase release of the engineered E. Coli, liberating the content of the nanoparticle. The nanoparticles made of gelatin are able to carry any type of organic compound leading to a wide range of applications.


Wiki Links

Retrieved from "http://2013.igem.org/Team:EPF_Lausanne"