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EPF_Lausanne’s team is proud to participate to iGEM 2013 and excited to present their project: Taxi.Coli: smart drug delivery. The team’s vision is to build a biosynthetic drug delivery concept. The key word of this project is “adaptability”. Our goal is to explore a way of using E.Coli as a highly modular carrier, opening the gate to several applications and alternatives in disease treatments. Using the principles of synthetic biology, we engineered a gelatinase secreting E. Coli able to bind gelatin nanoparticles using a biotin-streptavidin interaction and release their cargo in a corresponding location. The drug delivery system is built in three parts: 1) the nanoparticle binding and 2) the environment sensing that 3) triggers the gelatinase release of the engineered E. Coli, liberating the content of the nanoparticle.
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Medal requirements
Bronze medal
- Register the team, have fun in the competition.
- iGEM 2013 Judging form.
- Description of the team's project using the iGEM wiki and the team's parts using the Registry of Standard Biological Parts.
- present a Poster and Talk at the iGEM Jamboree.
- Document at least one new standard BioBrick Part and submit it to the Registry and a new application of a previously existing BioBrick part
Silver medal
- Req 2
- Req 2
- Req 2
Silver medal
- Req 1
- Req 2
- Req 2
- Req 2
Gold medal
- Req 1
- Req 2
- Req 2
- Req 2
