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We are proud to participate in IGEM 2013 and are looking forward to present
Taxi.Coli - smart drug delivery
The basic idea is quite simple: 1. nanoparticles incorporating drugs are the passengers 2. add streptavidin to the surface of E.coli as seats 3. use E.coli as the taxi 4. use pH or arabinose to release the drugs - GPS.
Our effort is limited to a proof of concept: - we can engineer biotynilated nanoparticles - we can engineer E.coli expressing streptavidin on the surface to bind these nanoparticles - we can calibrate E.coli to sense different levels of pH / arabinose - the release mechanism works.
This concept will be extremely flexible and adaptable because ...
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Medal requirements
Bronze medal
- Register the team, have fun in the competition.
- iGEM 2013 Judging form.
- Description of the team's project using the iGEM wiki and the team's parts using the Registry of Standard Biological Parts.
- Present a poster and talk at the iGEM Jamboree.
- Document at least one new standard BioBrick Part and submit it to the Registry + a new application and documentation of a previously existing BioBrick part in the Registry
Silver medal
- Experimentally validate that at least one new BioBrick Part of your own design and construction works as expected.
- Document the characterization of this part and submit this new part to the iGEM Parts Registry
- Implications for the environment, security, safety and ethics and/or ownership and sharing. Describe one or more ways in which these or other broader implications have been taken into consideration in the design and execution of your project.
Gold medal
- Improve the function of an existing BioBrick Part or Device
- Outline and detail a new approach to an issue of Human Practice in synthetic biology as it relates to your project, such as safety, security, ethics, or ownership, sharing, and innovation.
