Team:EPF Lausanne

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Revision as of 10:51, 3 October 2013

Taxi.Coli: Smart Drug Delivery iGEM EPFL

Header

Taxi.Coli: smart drug delivery

EPF_Lausanne’s team is proud to participate to iGEM 2013 and excited to present their project: Taxi.Coli: smart drug delivery. The team’s vision is to build a biosynthetic drug delivery concept. The key word of this project is “adaptability”. Our goal is to explore a way of using E.Coli as a highly modular carrier, opening the gate to several applications and alternatives in disease treatments. Using the principles of synthetic biology, we engineered a gelatinase secreting E. Coli able to bind gelatin nanoparticles using a biotin-streptavidin interaction and release their cargo in a corresponding location. The drug delivery system is built in three parts: 1) the nanoparticle binding and 2) the environment sensing that 3) triggers the gelatinase release of the engineered E. Coli, liberating the content of the nanoparticle.

Please also visit our Facebook page!

Team-EPF-Lausanne overview1.jpg
Team-EPF-Lausanne overview2.jpg


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