Team:UESTC

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         <ul class="nav">
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<li>
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<a href="https://2013.igem.org/Team:UESTC">Home</a>
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<a href="https://2013.igem.org/Team:UESTC#" class="active_menu">Home</a>
</li>
</li>
<li>  
<li>  
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<a href="https://2013.igem.org/Team:UESTC/#project">Project</a>
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<a href="#project">Project</a>
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                     <li><a href="https://2013.igem.org/Team:UESTC/nebula">Nebula</a></li>
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                    <li><a href="https://2013.igem.org/Team:UESTC/transpeeder">Transpeeder</a></li>
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                            <p>jdkkjflajflajfljjalfjsafjl</p>
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<a href="https://2013.igem.org/Team:UESTC/#team_info">Team Info</a>
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<a href="https://2013.igem.org/Team:UESTC/team_info">Team Info</a>
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                            <p>jdkkjflajflajfljjalfjsafjl</p>
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<a href="https://2013.igem.org/Team:UESTC/#notebook">Notebook</a>
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<a href="https://2013.igem.org/Team:UESTC/notebook">Notebook</a>
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                <ul>
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                        details
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<a href="https://2013.igem.org/Team:UESTC/#mf">Medal Fufillment</a>
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<a href="https://2013.igem.org/Team:UESTC/mf">Medal Fulfillment</a>
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<a href="https://2013.igem.org/Team:UESTC/#hp">Human Practice</a>
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<a href="https://2013.igem.org/Team:UESTC/human_practice">Human Practice</a>
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</li>
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<li>
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<a href="#">Others</a>
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<ul>
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<li><a href="https://2013.igem.org/Team:UESTC/safety">Safety</a></li>
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<li><a href="https://2013.igem.org/Team:UESTC/submission">Submission</a></li>
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</ul>
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             <p>(University of Electronic Science and Technology of China)</p>
             <p>(University of Electronic Science and Technology of China)</p>
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     <div class="panel" id="project">
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         <span>Projects</span>
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        <div id="nebula-show" class="proj_show">
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            <div data-thumb="" data-src="https://static.igem.org/mediawiki/2013/6/6d/UESTC_proj1.jpg">
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        <h1>Nebula</h1>
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                <div class="camera_caption fadeFromBottom">
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<p class="pp">Nebula (Network of Elaborated Biobricks based on User Locating and Automation) is a biological circuit design tool composed of Auto Mode & Manual Mode.</p>
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                    <h1>Blueprint</h1>
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<a href="https://2013.igem.org/Team:UESTC/nebula" class="pp">Learn more</a>
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                        <p>No matter who you are, a scientist proficient in synthetic biology or a greenhand who only cares about
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<img src="https://static.igem.org/mediawiki/2013/e/ee/UESTC_proj_1.jpg">
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                                            output, Blueprint is your best choice. Two major parts are provided: Interactive part & Automatic part.
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        </div>
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                                            In the first part, you are free to get what you want linking any parts we provide. But you have to make sense,
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        <div id="transpeeder-show" class="proj_show">
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                                            of course. In the second part, the only thing you need to do is to determine the inducer and the output.
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        <h1>Transpeeder</h1>
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                                            Then, you can sit back and wait for our software to provide you with the optimized circuit. Wow!</p>
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        <p class="pp">Transpeeder will help you to control your gene translation velocity by providing you a fast and a slow mutated sequence.</p>
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                </div>
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        <a href="https://2013.igem.org/Team:UESTC/transpeeder" class="pp">Learn more</a>
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            </div>
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        <img src="https://static.igem.org/mediawiki/2013/f/f8/UESTC_proj_2.png">
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         </div>
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                    <h1>Transpeeder</h1>
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                        <p>The satisfying amino acid or nucleic acid sequences that the user submitted will be compared to the chosen
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                                            CD sequences by ClustalW, the sequence which has highest similarity with SD sequences are defined as the
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                                            slow-translating sequence, on the contrary, the one which has lowest similarity with SD sequences are defined
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                                            as the fast-translating sequence.</p>
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                </div>
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                    <h1>iBricks</h1>
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                    <p>  iBricks is an iphone game concerning synthetic biology.
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  In this game, what you need to do is to synthesize protein to compound a cell.
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  You are provided with several basic parts to synthesize protein.
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  Once you accomplish combining these parts into a circuit, you will enter into transcription process, during which phage will continuously attack your circuit.
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  To protect it, you can press on these phages to kill them.
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  You can also utilize several tools to eliminate phages with higher efficiency.
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  After successfully synthesizing the protein, you can get new parts that increase the possibility of successfully synthesizing proteins.
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  With several synthesized proteins, you can accomplish the goal of synthesizing a complete cell.</p>
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            <h1>Hello</h1>
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            <p>This is the voice from UESTC, Chengdu, China.
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  We are proud to announce that we have achieved two first here: It‘s the first time that our university take part in iGEM. What’s more, we are also the first team from the southwest region of China participating in the software competition. Wow!
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  We come from University of electronic science and technology of China, which is renowned as China's cradle for the national electronic industry.
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  Also, our universty is situated at Chengdu, the city of over a thousand-year-old cultural history in 'the land of abundance' What's more, we are from the hometown of PANDAs! </p>
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                <h1>Student Members</h1>
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                        <ul id="mem1_content">
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                            <li><p>Hi, I am the leader of our team and the director of iBricks. Being as a
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                                junior student majoring in Biomedical Engineering, I have great interest in
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                                data mining in social network and programming software on mobile devices. I
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                                did all the scoring algorithm of Blueprint in our team.</p>
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                        <span class="mem_name">Muruo Liu</span>
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                            <li><p>Hi, I am a junior student from school of life science and technology,
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                                majoring in Biomedical Engineering and minoring in English. For my great
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                                organizational capability, I am the director of Blueprint. I am in charge
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                                of the statistics of parts in the registry and database established for Blueprint.</p>
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                        <span class="mem_name">Xiaonan Guo</span>
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                        <ul id="mem3_content">
+
-
                            <li><p>Hi, I am a junior student majoring in Biomedical Engineering. I am fond of
+
-
                                photography and sports, especially basketball. I did part of parts statistics
+
-
                                and the realization of Transpeeder by Java.</p>
+
-
                            </li>
+
-
                        </ul>
+
-
                        <span class="mem_name">Yingping Han</span>
+
-
                    </li>
+
-
                    <li>
+
-
                        <script language="javascript" type="text/javascript">
+
-
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+
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                            });
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                        </script>
+
-
                        <img id="mem4" src="https://static.igem.org/mediawiki/2013/e/ee/UESTC_Jurong_Zhao.jpg" />
+
-
                        <ul id="mem4_content">
+
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                            <li><p>Hi, I am a junior student majoring in Biomedical Engineering with strong
+
-
                                learning ability. I like running, reading and traveling around. I did part
+
-
                                of parts statistics and kept the minutes of our discussion in our way to MIT.
+
-
                                My life motto is nothing is impossible to a willing heart.</p>
+
-
                            </li>
+
-
                        </ul>
+
-
                        <span class="mem_name">Jurong Zhao</span>
+
-
                    </li>
+
-
                    <li>
+
-
                        <script language="javascript" type="text/javascript">
+
-
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+
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+
-
                                    tip_content_border_color: 'blue',
+
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                                    tip_content_width: '250',
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                            });
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                        </script>
+
-
                        <img id="mem5" src="https://static.igem.org/mediawiki/2013/b/b3/UESTC_Wenpin_Xiang.jpg" />
+
-
                        <ul id="mem5_content">
+
-
                            <li><p>Hi, I am a junior student majoring in Biomedical Engineering with great interest
+
-
                                in programming. I chose programming on IOS system as the main attack. iBricks is my
+
-
                                first experience in video games. Programming Blueprint on iphone is relatively easy
+
-
                                to me. My maxim is where there is a will, there is a way.</p>
+
-
                            </li>
+
-
                        </ul>
+
-
                        <span class="mem_name">Wenpin Xiang</span>
+
-
                    </li>
+
-
                    <li>
+
-
                        <script language="javascript" type="text/javascript">
+
-
                            $jq123(function () {
+
-
                                $jq123("#mem6").webwidget_tip_imagesAdSense({
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                                    tip_content_font_color: '#666',
+
-
                                    tip_content_background_color: '#FFF',
+
-
                                    tip_content_border_color: 'blue',
+
-
                                    tip_content_width: '250',
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                                    tip_position: 'right',
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+
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                            });
+
-
                        </script>
+
-
                        <img id="mem6" src="https://static.igem.org/mediawiki/2013/4/40/UESTC_Guodong_Zhu.jpg" />
+
-
                        <ul id="mem6_content">
+
-
                            <li><p>Hi, I am a sophomore majoring in Theoretical Physics from school of physical
+
-
                                electronics. I am regarded as a hard-working student with easy-going personality.
+
-
                                Making great videos is what I am always pursuing. Besides this, I also participated
+
-
                                in parts statistics work for our projects.</p>
+
-
                            </li>
+
-
                        </ul>
+
-
                        <span class="mem_name">Guodong Zhu</span>
+
-
                    </li>
+
-
                    <li>
+
-
                        <script language="javascript" type="text/javascript">
+
-
                            $jq123(function () {
+
-
                                $jq123("#mem7").webwidget_tip_imagesAdSense({
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                                    tip_button_style: 'notepaper',
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                                    tip_content_background_color: '#FFF',
+
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                                    tip_content_border_color: 'blue',
+
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                                    tip_content_width: '250',
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                                    tip_position: 'right',
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+
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+
-
                            });
+
-
                        </script>
+
-
                        <img id="mem7" src="https://static.igem.org/mediawiki/2013/7/75/UESTC_Yang_Xue.jpg" />
+
-
                        <ul id="mem7_content">
+
-
                            <li><p>Hi, I am a freshman from School of Information and Software Engineering,
+
-
                                also a fantastic guy with passion and great imagination. Wiki is rather a great
+
-
                                challenge for me, but I really enjoy this process, learning and progressing.
+
-
                                The realization of Blueprint is also my work. I expected to show you a grand map
+
-
                                of parts distributed in 2013 by iGEM.</p>
+
-
                            </li>
+
-
                        </ul>
+
-
                        <span class="mem_name">Yang Xue</span>
+
-
                    </li>
+
-
                </ul>
+
-
            </div><!-- end of #student_members -->
+
-
            <div class="mem_panel" id="advisors">
+
-
                <h1>Advisors</h1>
+
-
                <ul class="mem_list">
+
-
                    <li>
+
-
                        <script language="javascript" type="text/javascript">
+
-
                            $jq123(function () {
+
-
                                $jq123("#mem8").webwidget_tip_imagesAdSense({
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                                    tip_button_style: 'notepaper',
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                                    tip_content_font_color: '#666',
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-
                                    tip_content_background_color: '#FFF',
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-
                                    tip_content_border_color: 'blue',
+
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                                    tip_content_width: '250',
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+
-
                            });
+
-
                        </script>
+
-
                        <img id="mem8" src="https://static.igem.org/mediawiki/2013/0/00/UESTC_Shangnian_Wang.jpg" />
+
-
                        <ul id="mem8_content">
+
-
                            <li><p>Hi, I am a graduate student majoring in biochemistry and molecular biology,
+
-
                                responsible for giving advice on some of the arts designing work in our team,
+
-
                                including T-shirts and wiki design.</p>
+
-
                            </li>
+
-
                        </ul>
+
-
                        <span class="mem_name">Shangnian Wang</span>
+
-
                    </li>
+
-
                    <li>
+
-
                        <script language="javascript" type="text/javascript">
+
-
                            $jq123(function () {
+
-
                                $jq123("#mem9").webwidget_tip_imagesAdSense({
+
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                                    tip_button_style: 'notepaper',
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+
-
                                    tip_content_font_color: '#666',
+
-
                                    tip_content_background_color: '#FFF',
+
-
                                    tip_content_border_color: 'blue',
+
-
                                    tip_content_width: '250',
+
-
                                    tip_position: 'right',
+
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+
-
                                });
+
-
                            });
+
-
                        </script>
+
-
                        <img id="mem9" src="https://static.igem.org/mediawiki/2013/9/99/UESTC_Yuannong_Ye.jpg" />
+
-
                        <ul id="mem9_content">
+
-
                            <li><p>Hi, I am a doctoral student in CEFG.Current Research interests: codon usage,
+
-
                                bioinformatic database. I did  algorithm of visualization of Blueprint and Transpeeder.</p>
+
-
                            </li>
+
-
                        </ul>
+
-
                        <span class="mem_name">Yuannong Ye</span>
+
-
                    </li>
+
-
                </ul>
+
-
            </div><!-- end of #advisors -->
+
-
            <div class="mem_panel" id="instructors">
+
-
                <h1>Instructors</h1>
+
-
                <ul class="mem_list">
+
-
                    <li>
+
-
                        <script language="javascript" type="text/javascript">
+
-
                            $jq123(function () {
+
-
                                $jq123("#mem10").webwidget_tip_imagesAdSense({
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                                    tip_button_style: 'notepaper',
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                                    tip_content_font_color: '#666',
+
-
                                    tip_content_background_color: '#FFF',
+
-
                                    tip_content_border_color: 'blue',
+
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                                    tip_content_width: '250',
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                                });
+
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                            });
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                        </script>
+
-
                        <img id="mem10" src="https://static.igem.org/mediawiki/2013/f/f5/UESTC_Jian_Huang.jpg" />
+
-
                        <ul id="mem10_content">
+
-
                            <li><p>Dr Jian Huang is a professor in the University of Electronic Science and Technology of China.
+
-
                                He holds M.D. degree with experience in medicine, basic immunology and bioinformatics from the
+
-
                                West China University of Medical Sciences and the Kyoto University. His studies focus on the molecular
+
-
                                aspects of antigens, antibodies and peptide aptamers. His work has resulted in the development of a few
+
-
                                immunological databases and web programs which have become to be important tools and data resources for both
+
-
                                computationalbiologists and experimental biologists, especially those using phage display technology.</p>
+
-
                                <p>For more information, please visit his homepage <a href="http://immunet.cn/hlab">http://immunet.cn/hlab</a></p>
+
-
                            </li>
+
-
                        </ul>
+
-
                        <span class="mem_name">Jian Huang</span>
+
-
                    </li>
+
-
                    <li>
+
-
                        <script language="javascript" type="text/javascript">
+
-
                            $jq123(function () {
+
-
                                $jq123("#mem11").webwidget_tip_imagesAdSense({
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                                    tip_content_background_color: '#FFF',
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                                    tip_content_border_color: 'blue',
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                            });
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+
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                        <img id="mem11" src="https://static.igem.org/mediawiki/2013/6/6a/UESTC_Hao_Lin.jpg" />
+
-
                        <ul id="mem11_content">
+
-
                            <li><p>Dr Lin is an associate professor of the Center of Bioinformatics in the
+
-
                                School of Life Science and Technology interested in proteomics bioinformatics and system biology.</p>
+
-
                              <p>For more information, please visit <a href="http://lin.uestc.edu.cn/">http://lin.uestc.edu.cn/</a></p>
+
-
                            </li>
+
-
                        </ul>
+
-
                        <span class="mem_name">Hao Lin</span>
+
-
                    </li>
+
-
                    <li>
+
-
                        <script language="javascript" type="text/javascript">
+
-
                            $jq123(function () {
+
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                                $jq123("#mem12").webwidget_tip_imagesAdSense({
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+
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+
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                            <li><p>Dr. Xianlong Wang is an associate professor of computational chemistry and biology
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                                at the Center of Bioinformatics, the University of Electronic Science and Technology of China.
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                                He is interested in modelling both small molecules and biological macromolecules and developing new algorithms.</p>
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                        <span class="mem_name">Xianlong Wang</span>
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                    <span>Shahe Campus:No.4, Section 2, North Jianshe Road, 610054</span>
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                    <li class="menu-toc-current"><a href="#item1">May</a></li>
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                    <li><a href="#item2">June</a></li>
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                                <h2>Diaries in May</h2>
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                                <h3>Friday  May 3, 2013</h3>
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                <p>The university tryouts which has lasted for nearly a month ended, and the name list of the selected members of the school team has been determined. Launching ceremony of the iGEM event this year was staged today and the people present are Dezhong Yao, Dean of School of Life; Qiong Zhang, vice secretary of the Communist Party Committee of School of Life; Jian Huang, supervisor of the software team; Xuelian Zheng, supervisor of the Wetware team and all members of the UESTC iGEM team. The leaders conveyed the great attention and expectations from the university.</p>
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                                <h3>Saturday  May 4, 2013</h3>
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                <p>It is the first meeting that was convened by the software team. Apart from the team members, the people who attended were the supervisors and the advisors. We discussed the schedule and main tasks at this stage and the team leader emphasized the discipline required during the preparations for iGEM. In May, we plan to do massive reading of academic papers on synthetic biology and each member is required to share the ideas that he or she has got from reading these papers, and then the team will discuss the ideas and make a decision on a general direction of our project. In June, the team is to do the intensive reading on the major direction and conceive frame of the project and assign tasks to each team member. In July and August, all members are to dedicate their time to the work distributed to him or her. In late August and September, the project will be under optimizing and improving, and the team will make preparations for the presentation to be held in Hong Kong.</p>
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                                <h3>Friday  May 10, 2013</h3>
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                                <p>We shared six papers in this meeting, the paper “Synthetic biology: New engineering rules for an emerging discipline” introduced some new engineering rules on synthetic biology; the paper “Engineering microbial consortia: a new frontier in synthetic biology” discussed the relationships between commensalism, amensalism symbiosis, mutualism, and parasitism from the perspective of synthetic biology; the paper “Protein promiscuity and its implications for biotechnology” introduced the application of protein engineering in synthetic biology;  the paper “Synthetic biology: Applications come of age” summarized the challenges and opportunities of synthetic biology; the paper “Synthetic biology projects in vitro” introduced in vitro synthesis of bioengineering and artificial life as well as the idea of minimal gene design method. After the discussion we had a deeper understanding of the idea of synthetic biology.</p>
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                                <h3>Sunday  May 12, 2013</h3>
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                                <p>In this meeting we discussed eight reviews read by the team members during the past several days. The contents of the reviews are in the areas of gene switch which is based on the research of protein isomerism; mammalian cell structure design using the idea of engineering of small molecules; synonymous codon bias; application of catalytic efficiency of light in synthetic biology reactions and RNA functions. The software Notebook done by other team for past competition was also introduced. Considering what we have already discussed before, we decided to focus more on the projects from the past iGEM teams. Now the topic that interests us is codon optimization based on selection bias, but it calls for  further discussion.</p>
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                                <h3>Friday  May 17, 2013</h3>
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                                <p>In this meeting we discussed four papers and some software. “SynBioSS: the synthetic biology modeling suite” is a synthetic gene structure modeling and simulation software in which different parts could be set in a complete network, but it highly recommends a wider and more comprehensive knowledge on synthetic biology, molecular biology and computers. Another paper talked about how antibiotics kill bacteria, and what we can learn from it is the possibility to create a piece of software to simulate this process, which, of course,will provide great convenience to synthetic biology researchers. Yang Xue introduced SBOL to the team, which is an open language for synthetic biology. “Engineering of synthetic intercellular communication systems” summarized how to accomplish cell communication systems in cells in synthetic biology. The software Bioguide introduced by Jurong Zhao focused on the categories for pathway generation and database search. After the discussion, we all agreed that the project we plan to do should be fully considered with the user needs and provide convenience to synthetic biology researchers.</p>
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                                <h3>Sunday  May 19, 2013</h3>
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                                <p>This discussion is mainly on software and biobricks as well as the CLOTHO platform. We talked about the ideas of the software finished by the team Wellesley_HCT_2012, UTP_Software_2012 and USTC_Software_2012 and their advantages, disadvantages and use value, which are inspiring to our own projects.</p>
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                                <h3>Wednesday  May 22, 2013</h3>
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                                <p>We talked about the software MGEC finished by the team Edinburgh _2008, which was designed for biologists to establish genetic engineering circuit model more easily based on modeling and data analysis. Another piece of software we discussed is BioBrick Manager_2010 which is mainly designed to connect Biobrick parts, and then to save as XML file. We also analyzed their disadvantages that need to be improved.</p>
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                                <h3>Friday  May 24, 2013</h3>
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                                <p>In this meeting, we discussed some pieces of software of the iGEM competitions before. For examples, Synthetic Biology Simulation Software: measuring the efficiency of the terminator; Digital Synthetic Gene Circuit Software (which can not perform large-scale optimization), then we thought about what we can do about it. USTC 2012 Software: Anti-circuit design was also introduced.. This time, we discussed a relatively new paper on anti-SD sequence, and the question that whether we can create a piece of software on codon optimization. So after the meeting, we should research this literature intensively to understand how to use the anti-SD sequence to achieve codon optimization and whether someone has already done similar software. Then we should study the corresponding data on RBS site, and grasp the information from compared sequences. More details will be finalized in next meeting.</p>
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                                <h3>Sunday  May 26, 2013</h3>
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                                <p>Today, we continued to discuss some software. Such as Tinker Cell which is a synthetic biology CAD software, in which analysis and biological networks are visualized by third-party C or C + + as well as python modules. And CAD tools, databases, a rule of network Design and a language Kera, GenoCAD, and network concepts were also introduced by different team members. Finally, we summarized the software discussed and drew some conclusions for our projects.</p>
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                                <h3>Friday  May 29, 2013</h3>
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                                <p>CLOTHO platform is a way that can be considered for making software. Also we discussed M4B (with its network structures, including a relatively new scoring rules for parts), and Synbioss. And we studied the python scripting language. This time, a new idea was proposed by Xiaonan Guo, which is to make a phone-based game in order to popularize synthetic biology and concept of biobricks. People can learn some knowledge on synthetic biology in their leisure time. The proposal interested us a lot and we need to check more information. Before we began to realize this idea, there are a lot of tasks to be done.</p>
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                                <h3>Wednesday  May 31, 2013</h3>
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                                <p>For the implementation of the idea we discussed last time, we also need to do a lot of work, and in which deep research is essential. We learned a lot from the game--USTC 2010 IGAME, such as the interface design, understanding a good sense from the perspective of a player. We also discussed AMDL (automatic modeling database language), the smallest gene design software. Last but not the least, we made the plan for the refinement of the game idea proposed last Friday, and discussed the direction and so on. Projects are in progress.</p>
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                                <h2>Diaries in June</h2>
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                                <h3>Sunday  June 2, 2013</h3>
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                <p>We continued to discuss some software we’ve collected, including Plasmid Automatic Design Software. And from its idea and approaches we can think about how to combine our game and the concept of synthetic biology. Other pieces of software we discussed are BioBricks jtools, which is a small set of utilities; Biomortar, EvoGents, focusing on how to make gene circuits stable based on genetic algorithms; and Agent Based System. Then, we determined agenda for the next meeting. In addition, the coach told us that Gil-- MIT judger -- would come to communicate with  us in our college.</p>
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            <h3>Tuesday  June 4, 2013</h3>
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                <p>Software we discussed are: Lachesis, a visualization tool based on parametric models. We talked about a literature which introduced how to choose a route from massive biobrick parts by scoring and the feasibility of the parts in the database. Biodesign is a program which automatically connects the selected parts, but it only supports IOS Systems. ABCD which was made by the USTC in 2009 can automatically generate the designed circuit. We also discussed Gil’s trip and our presentations.</p>
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Latest revision as of 13:37, 28 October 2013

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Hello,welcome to visit our Wiki, for better view, please use chrome, firefox, safari .etc modern browser.

main

Hi! We are 2013 iGEM Competition Software Team UESTC

(University of Electronic Science and Technology of China)

Projects

Nebula

Nebula (Network of Elaborated Biobricks based on User Locating and Automation) is a biological circuit design tool composed of Auto Mode & Manual Mode.

Learn more

Transpeeder

Transpeeder will help you to control your gene translation velocity by providing you a fast and a slow mutated sequence.

Learn more