Team:XMU-China/Content

 

<p>Oscillations permeate every corner of the world, from the alternative current （AC） in power lines to our tiny microorganism friends. To use oscillations in bacteria as a strong and steady signal transmission method like AC, we need to tackle with the noise of transcription and translation in the cellular environment by coupling millions of cells through the synchronizing genetic oscillations in E.coli. At the colony level cells could be synchronized via quorum sensing, which is limited to tens of micrometers by the AHL, and between colonies a gas-phase redox (mainly H2O2) will serve as a signal that can give positive feedback to the whole circuit over millimeter scales simultaneously. On a liquid crystal display (LCD)-like microfluidic array bacteria grow in separate colonies, so that synchronization in both levels could be verified visually. Now a robust synthetic biology signal converter is accomplished and ready to show the growth environment of cells.<br>

<p>We coded two software by Matlab related our experiment.<br/>

First one is Gene OS, the model of oscillation which simulates our circuit and compares various results with different initial conditions. This gave us a deeper understanding about the mechanism.<br/>

The other one is ImageMe which offers batch processing function and reduces much of time in analyzing the microfluidic images.<br/>

<p>Our team has held a series of events as human practice. Throughout the whole July, we has drawn a doodle about iGEM, held a garden party and exhibition, made a questionnaire survey and hosted a synthetic biology lecture.<br/>  

<p>Nowadays, more and more people tend to build an environmentally friendly society and take more seriously about the safety issues of wet lab.<br/>  

A series of other measurements were taken to reach the safety requirements.<br/>  

<a href="https://2013.igem.org/Team:XMU-China/Safety1">Read more</a>

 

<div class="clear"></div>   

<img src="https://static.igem.org/mediawiki/2013/c/cb/Xmusoftware_sponsor1.png" width="120px" height="120px">

<img src="https://static.igem.org/mediawiki/2013/1/18/Xmusoftware_sponsor2.png" width="120px" height="120px">

<img src="https://static.igem.org/mediawiki/2013/7/7f/Xmusoftware_sponsor3.png" width="120px" height="120px">

<img src="https://static.igem.org/mediawiki/2013/6/6c/Xmusoftware_sponsor4.png" width="120px" height="120px">

<img src="https://static.igem.org/mediawiki/2013/6/66/Xmusoftware_sponsor5.png" width="120px" height="120px">

<img src="https://static.igem.org/mediawiki/2013/7/77/Xmusoftware_sponsor6.png" width="120px" height="120px">

<li><a href="https://2013.igem.org/Team:XMU-China/Human Practice">Human Practice</a></li>

</ul>

<div id="clustrmaps-widget"></div><script type="text/javascript">var _clustrmaps = {'url' : 'https://2013.igem.org/Team:XMU-China', 'user' : 1108031, 'server' : '2', 'id' : 'clustrmaps-widget', 'version' : 1, 'date' : '2013-09-24', 'lang' : 'zh', 'corners' : 'square' };(function (){ var s = document.createElement('script'); s.type = 'text/javascript'; s.async = true; s.src = 'http://www2.clustrmaps.com/counter/map.js'; var x = document.getElementsByTagName('script')[0]; x.parentNode.insertBefore(s, x);})();</script><noscript><a href="http://www2.clustrmaps.com/user/c2810e83f"><img src="http://www2.clustrmaps.com/stats/maps-no_clusters/2013.igem.org-Team-XMU-China-thumb.jpg" alt="Locations of visitors to this page" /></a></noscript>

<div class="copyright">&copy; Copyright &copy; 2013.XMU-China iGEM All rights reserved.</div>