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Team:Paris Bettencourt
From 2013.igem.org
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<div class="cont"><p style="font-size:32px;line-height:34px;">FIGHT TUBERCULOSIS WITH MODERN WEAPONS </p></div> | <div class="cont"><p style="font-size:32px;line-height:34px;">FIGHT TUBERCULOSIS WITH MODERN WEAPONS </p></div> | ||
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| - | Tuberculosis (TB) is an infectious disease caused by <i>Mycobacterium tuberculosis</i> (Mtb) that affects nearly two billion people around the world. On this website we present four new ways to use the power of synthetic biology in the fight against TB | + | Tuberculosis (TB) is an infectious disease caused by <i>Mycobacterium tuberculosis</i> (Mtb) that affects nearly two billion people around the world. On this website we present four new ways to use the power of synthetic biology in the fight against TB; from TB detection, to drug targeting, to infiltrating macrophages, to sabotaging the synthesis of proteins. |
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Revision as of 03:29, 5 October 2013
FIGHT TUBERCULOSIS WITH MODERN WEAPONS
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (Mtb) that affects nearly two billion people around the world. On this website we present four new ways to use the power of synthetic biology in the fight against TB; from TB detection, to drug targeting, to infiltrating macrophages, to sabotaging the synthesis of proteins.
A biosensor that detects the presence of sequence specific antibiotic resistance genes.
A safe and specific high-throughput drug screening method that targets essential mycobacterial metabolic proteins.
A phage system with low fitness cost producing sRNA, which inhibit the synthesis of antibiotic resistance proteins.
Infiltrate macrophages with an E.coli producing TDMH, an enzyme that will lyse the Mycobacteria cell wall.
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team2013@igem-paris.org 
