"
Team:Uppsala/metabolic-engineering
From 2013.igem.org
Sabrijamal (Talk | contribs) |
Sabrijamal (Talk | contribs) |
||
| Line 149: | Line 149: | ||
<div id="container_mini_pic"> | <div id="container_mini_pic"> | ||
| - | <div id="coumeric_div"> | + | <div class="text_box_in_the_box" id="coumeric_div"> |
<a href="https://2013.igem.org/Team:Uppsala/p-coumaric-acid"> | <a href="https://2013.igem.org/Team:Uppsala/p-coumaric-acid"> | ||
<div id="substance_title"> <h3> P-coumaric acid </h3> </div> | <div id="substance_title"> <h3> P-coumaric acid </h3> </div> | ||
| Line 163: | Line 163: | ||
</div> | </div> | ||
| - | <div id="resveratrol_div"> | + | </div> |
| + | |||
| + | <div class="text_box_in_the_box" id="resveratrol_div"> | ||
<a href="https://2013.igem.org/Team:Uppsala/resveratrol"> | <a href="https://2013.igem.org/Team:Uppsala/resveratrol"> | ||
<div id="substance_title"> <h3> Resveratrol </h3> </div> | <div id="substance_title"> <h3> Resveratrol </h3> </div> | ||
| Line 175: | Line 177: | ||
</div> | </div> | ||
</div> | </div> | ||
| + | </div> | ||
| - | + | <div class="text_box_in_the_box" id="lycopene_div"> | |
| - | <div id="lycopene_div"> | + | |
<a href="https://2013.igem.org/Team:Uppsala/lycopene"> | <a href="https://2013.igem.org/Team:Uppsala/lycopene"> | ||
<div id="substance_title"> <h3> Lycopene </h3> </div> | <div id="substance_title"> <h3> Lycopene </h3> </div> | ||
| Line 190: | Line 192: | ||
</div> | </div> | ||
| - | <div id="beta_carotene_div"> | + | </div> |
| + | |||
| + | <div class="text_box_in_the_box" id="beta_carotene_div"> | ||
<a href="https://2013.igem.org/Team:Uppsala/betacarotene"> | <a href="https://2013.igem.org/Team:Uppsala/betacarotene"> | ||
<div id="substance_title"> <h3> β-carotene </h3> </div> | <div id="substance_title"> <h3> β-carotene </h3> </div> | ||
| Line 203: | Line 207: | ||
</div> | </div> | ||
</div> | </div> | ||
| + | </div> | ||
| Line 233: | Line 238: | ||
</div> | </div> | ||
| - | + | <div class="text_box_in_the_box"d="saffron_div"> | |
<a href="https://2013.igem.org/Team:Uppsala/saffron"> | <a href="https://2013.igem.org/Team:Uppsala/saffron"> | ||
<div id="substance_title"> <h3> Saffron </h3> </div> | <div id="substance_title"> <h3> Saffron </h3> </div> | ||
| Line 244: | Line 249: | ||
</div> | </div> | ||
</div> | </div> | ||
| + | |||
| + | </div> | ||
</div> <!-- closing div for container_mini_pic --> | </div> <!-- closing div for container_mini_pic --> | ||
Revision as of 02:28, 29 September 2013
Metabolic Engineering
We have aimed our project at producing food nutrients in bacteria. These nutrients normally exists in for example carrots, tomatoes, garlic, grapes and several other important food. By transferring genes from plants and fruits we can make our bacteria produce vital nutrients and commercially attractive supplements. We alter the metabolic pathways of our bacteria by introducing new genes or by modifying existing pathways.
Organic materia produced by nature is one of our main sources of energy. For billions of years, nature has perfected its machinery. We get fuel from both fossilized organisms and renewable biomateria. All life on earth is dependent of getting the right amount of food and nutrition. As we become more and more people on earth, we need to optimize our techniques for food and nutritional production. This is where we can step in and alter natures machinery.
P-coumaric acid
P-coumaric acid is an antioxidant that is produced from tyrosin by the enzyme Tyrosine ammonia lyase (TAL). This antioxidant has been shown to have many health benefits. For example studies have shown that it can reduce the risk of atherosclerosis and also reduce the risk of stomach cancer. P-coumaric acid can be found foods such as peanuts, garlic, wine and vinegar.
Resveratrol
Resveratrol belongs to a group of molecules known as Phyloalexin which is used by many plants to battle infections of all sorts. Many studies have been done on resveratrol showing it has a wide range of beneficial properties ranging from skin cancer reduction to anti-inflamatory effects and antioxidant properties. Perhaps the most interesting property is that of life extension.
Lycopene
Lycopene is a carotenoid that primarily derives from the xanthophyll group. The precursor responsible for lycopene production is phytoene, when present together with the enzyme CrtE a catalytic reaction takes place and lycopene is produced. Lycopene is an antioxidant that can be found in both vegetables and fruits, it is mostly known for its characteristic red color in tomatoes.
β-carotene
β-carotene is a precursor of substances such as Vitamin A, zeaxanthine and asthaxanthine. β-carotene is a derive from Lycopene and is commonly known for its characteristic orange color, it is found in fruits and vegetables. Vitamin A which is a derive from β-carotene has important health aspects for our skin, different membranes and most commonly known our eyes.
Astaxanthin
Astaxanthin is a carotenoid pigment that derives from the xanthophyll group and is most known for giving the red color of salmon, lobster and shrimp. Astaxanthin is a very strong antioxidant and is produced using the microalgae Haematococcus or synthetically. The substance costs around 2500 US dollars per kg and is often used in fishfarming to give salmon its red color.
Zeaxanthin
