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Team:Dundee/Project/MathOverview
From 2013.igem.org
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<div class="span6" style="text-align:justify"> | <div class="span6" style="text-align:justify"> | ||
<h2 style="margin-top:-10px;"> PP1 Capacities </h2> | <h2 style="margin-top:-10px;"> PP1 Capacities </h2> | ||
| - | <p> The | + | <p> The PP1 capacities of <i>E. coli</i> and <i>B. subtilis</i> were investigated in order to determine which chassis could host the greatest number of PP1 molecules. This analysis indicated that <i>E. coli</i> has the capacitive potential to be a more efficient mop than <i>B. subtilis</i>. </p> |
</div> | </div> | ||
<div class="span6" style="text-align:justify"> | <div class="span6" style="text-align:justify"> | ||
<h2 style="margin-top:-10px;"> Production & Export</h2> | <h2 style="margin-top:-10px;"> Production & Export</h2> | ||
| - | <p> | + | <p>We developed a Production & Export model to help us predict the number of PP1 we could transport into the periplasm of our ToxiMop cells. The model allowed us to optimise the construction of our prototype ToxiMop.</p> |
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</div> | </div> | ||
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<div class="span6" style="text-align:justify"> | <div class="span6" style="text-align:justify"> | ||
<h2 style="margin-top:-10px;"> Mop Simulation </h2> | <h2 style="margin-top:-10px;"> Mop Simulation </h2> | ||
| - | <p> | + | <p>Visualisation tools investigating the biological processes which take place in the ToxiMop bacteria allow a user to alter the key properties of the transport mechanisms and provide instant feedback on the results of such changes. |
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</p> | </p> | ||
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<div class="span6" style="text-align:justify"> | <div class="span6" style="text-align:justify"> | ||
<h2 style="margin-top:-10px;"> Detection Comparison</h2> | <h2 style="margin-top:-10px;"> Detection Comparison</h2> | ||
| - | <p> | + | <p>With current detection methods, time delays between the sampling and obtaining of results induces an increase in the microcystin concentrations. Therefore, an effective biological detector must reduce the detection time. </p> |
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</div> | </div> | ||
</div> | </div> | ||
Revision as of 13:02, 2 October 2013
Modelling Overview
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PP1 Capacities
The PP1 capacities of E. coli and B. subtilis were investigated in order to determine which chassis could host the greatest number of PP1 molecules. This analysis indicated that E. coli has the capacitive potential to be a more efficient mop than B. subtilis.
Production & Export
We developed a Production & Export model to help us predict the number of PP1 we could transport into the periplasm of our ToxiMop cells. The model allowed us to optimise the construction of our prototype ToxiMop.
Mop Simulation
Visualisation tools investigating the biological processes which take place in the ToxiMop bacteria allow a user to alter the key properties of the transport mechanisms and provide instant feedback on the results of such changes.
Detection Comparison
With current detection methods, time delays between the sampling and obtaining of results induces an increase in the microcystin concentrations. Therefore, an effective biological detector must reduce the detection time.
