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Team:Paris Bettencourt
From 2013.igem.org
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{{:Team:Paris_Bettencourt/Menu}} | {{:Team:Paris_Bettencourt/Menu}} | ||
<html> | <html> | ||
| - | |||
| - | |||
<style> | <style> | ||
| - | /* Top | + | /* Top Banner */ |
#topheader{ | #topheader{ | ||
display:block; | display:block; | ||
position:absolute; | position:absolute; | ||
| - | top:- | + | top:-15px; |
width:100%; | width:100%; | ||
margin-bottom:-120px; | margin-bottom:-120px; | ||
position:relative; | position:relative; | ||
| - | |||
} | } | ||
| - | # | + | #BotArrow{ |
| - | position: relative; | + | position: relative;- |
z-index:2; | z-index:2; | ||
| + | bottom:42px; | ||
| + | margin-bottom:-42px; | ||
} | } | ||
| - | # | + | #PBlogo { |
| - | position: relative | + | position:relative; |
| - | + | bottom:580px; | |
| - | bottom: | + | left:30px; |
| - | + | ||
} | } | ||
| + | /* Panels */ | ||
.panel { | .panel { | ||
| - | + | width:1100px; | |
| - | + | height:528px; | |
| - | + | margin:0; | |
| - | + | margin-bottom:0px; | |
| - | + | color: rgb(30,39,43); | |
| - | + | font-family: 'Yanone Kaffeesatz', sans-serif; | |
} | } | ||
| - | + | .panel a { | |
| - | . | + | color: rgb(46,43,52); |
| - | + | text-decoration:none; | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
} | } | ||
| - | . | + | /* Subpanels */ |
| - | + | .narrowimg {/* Subpanels background*/ | |
| - | + | /*position:absolute;*/ | |
| - | + | z-index:2; | |
| - | + | opacity:0.3; | |
| - | + | filter: alpha(opacity=30); | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
} | } | ||
| - | . | + | .titlebox {/* Subpanels Title*/ |
| - | + | z-index:1; | |
| - | + | position:relative; | |
| - | + | bottom:480px; | |
| - | + | background:transparent; | |
| - | + | ||
} | } | ||
| - | . | + | /* Project Panels*/ |
| - | + | .subpanel1 { /* Overview */ | |
| - | + | float:left; | |
| - | + | width:535px; | |
| - | + | height:428px; | |
| - | + | margin-top:0; | |
| - | + | margin-right:20px; | |
| - | + | margin-bottom:12px; | |
| - | + | border-radius:7px; | |
| - | + | background:rgb(252,250,229); | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
} | } | ||
| - | .spdesc { | + | .spdesc { /* Overview content */ |
| - | + | display:none; | |
| - | + | height:100px; | |
| - | + | color:rgb(30,39,43); | |
} | } | ||
| - | .cont { | + | .cont { /* Overview content */ |
| - | + | width:90%; | |
| - | + | height:auto; | |
| - | + | margin-left:5%; | |
| - | + | margin-top:5%; | |
| - | + | background:transparent; | |
} | } | ||
.cont p { | .cont p { | ||
| - | + | line-height:28px; | |
| - | + | width:auto; | |
| - | + | height:auto; | |
| - | + | margin:5% 2%; | |
| - | + | ||
} | } | ||
| - | . | + | .subpanel2 { /* Projects */ |
| - | + | float:left; | |
| - | + | width:125px; | |
| - | + | height:492px; | |
| - | + | font-size:22px; | |
| + | text-align:center; | ||
| + | margin-top:0; | ||
| + | margin-right:11px; | ||
| + | border-radius:7px; | ||
| + | overflow:hidden; | ||
} | } | ||
| - | . | + | .subpanel2:hover{ |
| - | + | font-weight:bold; | |
| - | + | ||
| - | + | ||
| - | + | ||
} | } | ||
| - | . | + | .subpanel2:hover .narrowimg { |
| - | + | opacity:0.8; | |
| - | + | filter: alpha(opacity=80); | |
} | } | ||
| - | . | + | .subpanel3 { /* Results */ |
| - | + | float:left; | |
| - | + | width:535px; | |
| - | + | height:50px; | |
| - | + | font-size:30px; | |
| - | + | text-align:left; | |
| - | + | line-height:50px; | |
| + | background:rgb(30,39,43); | ||
| + | color:white; | ||
| + | border-radius:7px; | ||
| + | position:relative; | ||
| + | bottom:50px; | ||
| + | font-family: 'Great Vibes', cursive; | ||
| + | font-size: 35px; | ||
} | } | ||
| - | . | + | /* Human Practice */ |
| - | + | .subpanel4 { /* divide page in 3 */ | |
| - | + | float:left; | |
| - | + | width:354px; | |
| - | + | height:492px; | |
| - | + | font-size:22px; | |
| - | + | margin-top:0; | |
| - | + | margin-right:18px; | |
| - | + | ||
| - | + | ||
} | } | ||
| - | . | + | .subpanel5 { /* TB Facts, TB in France, TB Gallery */ |
| - | + | height:156px; | |
| - | + | text-align:center; | |
| - | + | margin-bottom:11px; | |
| - | + | background:rgb(255,255,255); | |
| - | + | color:black; | |
| - | + | border-radius:7px; | |
| - | + | overflow:hidden; | |
| - | + | } | |
| - | + | .subpanel5:hover{ | |
| - | + | font-weight:bold; | |
| - | + | } | |
| + | .subpanel5:hover .narrowimg { | ||
| + | opacity:0.8; | ||
| + | filter: alpha(opacity=80); | ||
| + | } | ||
| + | .subpanel7 { /* Gender */ | ||
| + | float:left; | ||
| + | width:354px; | ||
| + | height:283px; | ||
| + | font-size:22px; | ||
| + | background:rgb(255,255,255); | ||
| + | color:black; | ||
| + | border-radius:7px; | ||
| + | overflow:hidden; | ||
| + | text-align:center; | ||
} | } | ||
.subpanel7:hover{ | .subpanel7:hover{ | ||
| - | + | font-weight:bold; | |
} | } | ||
| - | . | + | .subpanel7:hover .narrowimg { |
| - | + | opacity:0.8; | |
| - | + | filter: alpha(opacity=80); | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
} | } | ||
| - | . | + | .subpanel9 { /* Tech Transfer */ |
| - | + | float:left; | |
| + | width:354px; | ||
| + | height: 198px; | ||
| + | font-size:22px; | ||
| + | background:rgb(255,255,255); | ||
| + | color:black; | ||
| + | border-radius:7px; | ||
| + | overflow:hidden; | ||
| + | text-align:center; | ||
| + | margin-top:11px; | ||
| + | } | ||
| + | .subpanel9:hover .narrowimg { | ||
| + | opacity:0.8; | ||
| + | filter: alpha(opacity=80); | ||
| + | } | ||
| + | .subpanel9:hover{ | ||
| + | font-weight:bold; | ||
} | } | ||
| - | .subpanel6 { | + | .subpanel6 { /* Collaboration, SensiGEM */ |
| - | + | height:240.5px; | |
| - | + | margin:0; | |
| - | + | margin-bottom:11px; | |
| - | + | border-radius:7px; | |
| - | + | overflow:hidden; | |
| - | + | background:rgb(255,255,255); | |
| - | + | color:Black; | |
| + | text-align:center; | ||
} | } | ||
.subpanel6:hover{ | .subpanel6:hover{ | ||
| - | + | font-weight:bold; | |
} | } | ||
| + | .subpanel6:hover .narrowimg { | ||
| + | opacity:0.8; | ||
| + | filter: alpha(opacity=80); | ||
| + | } | ||
| + | /* Panels at the bottom */ | ||
.subpanel8 { | .subpanel8 { | ||
| - | + | float:left; | |
| - | + | height:96px; | |
| - | + | width:261.5px; | |
| - | + | margin-right:18px; | |
| - | + | border-radius:7px; | |
| - | + | overflow:hidden; | |
| - | + | background:rgb(30,39,43); | |
| - | + | color:white; | |
} | } | ||
.subpanel8 img { | .subpanel8 img { | ||
| - | + | margin-top:16px; | |
| - | + | background:white; | |
} | } | ||
.subpanel8 img:hover { | .subpanel8 img:hover { | ||
| - | + | background:rgb(252,250,229); | |
} | } | ||
</style> | </style> | ||
| - | <div id="topheader"> | + | <div id="topheader"> |
| - | + | <img style="margin-top:-1px" src="https://static.igem.org/mediawiki/2013/0/0a/PB_frontpagebanner7.png" width="1100px" height="632"/> | |
| - | + | <img id="BotArrow" src="https://static.igem.org/mediawiki/2013/7/7d/PB_Banner_Lines2.gif" width="1100px"> | |
| - | <img src="https://static.igem.org/mediawiki/2013/ | + | <img id="PBlogo" src="https://static.igem.org/mediawiki/2013/3/3a/PB_logoParis.gif" width="122px"/> |
</div> | </div> | ||
| - | + | <div style="clear: both;"></div> | |
| - | + | <script src="http://ajax.googleapis.com/ajax/libs/jquery/1.8.3/jquery.min.js"></script> | |
| - | <div style="clear: both;"></div> | + | <div id="page"> |
| - | <script src="http://ajax.googleapis.com/ajax/libs/jquery/1.8.3/jquery.min.js"></script> | + | <div class="panel"> |
| - | <div id="page"> | + | <a href="https://2013.igem.org/Team:Paris_Bettencourt/Project/Overview" title="Project Overview"> |
| - | + | <div class="subpanel1"> | |
| - | + | <div style="position:relative;bottom:0px"> | |
| - | <div class="panel"> | + | <div class="cont"><p style="font-size:32px;line-height:34px;">FIGHT TUBERCULOSIS WITH MODERN WEAPONS </p></div> |
| - | + | <div class="cont"> | |
| - | + | <p style="font-size:26px;"> | |
| - | + | Tuberculosis (TB) is an infectious disease caused by <i>Mycobacterium tuberculosis</i> (Mtb) that affects nearly two billion people around the world. On this website we present four new ways to use the power of synthetic biology in the fight against TB: from gene detection, to drug targeting, to infiltrating macrophages, to sabotaging the synthesis of proteins. Hover over these panels to see the project overview. | |
| - | + | </p> | |
| - | + | </div> | |
| - | + | <div id="psdesc" class="spdesc"> | |
| - | + | <div class="cont"> | |
| - | + | <p style="font-size:26px;">A biosensor that detects the presence of sequence specific antibiotic resistance genes.</p> | |
| - | + | </div> | |
| + | </div> | ||
| + | <div id="dsdesc" class="spdesc"> | ||
| + | <div class="cont"> | ||
| + | <p style="font-size:26px;">A safe and specific high-throughput drug screening method that targets essential mycobacterial metabolic proteins.</p> | ||
| + | </div> | ||
| + | </div> | ||
| + | <div id="thdesc" class="spdesc"> | ||
| + | <div class="cont"> | ||
| + | <p style="font-size:26px;">A phage system with low fitness cost producing sRNA, which inhibits the synthesis of antibiotic resistance proteins.</p> | ||
| + | </div> | ||
| + | </div> | ||
| + | <div id="tcdesc" class="spdesc"> | ||
| + | <div class="cont"> | ||
| + | <p style="font-size:26px;">Infiltrate macrophages with an <i>E.coli</i> producing TDMH, an enzyme that will lyse the Mycobacteria cell wall.</p> | ||
| + | </div> | ||
| + | </div> | ||
| + | </div> | ||
| + | </div> | ||
| + | </a> | ||
| + | <a href="https://2013.igem.org/Team:Paris_Bettencourt/Project/Detect" title="Detect"> | ||
| + | <div id="pspanel" class="subpanel2" onmouseover="chgtrans(this)"> | ||
| + | <img class="narrowimg" src="https://static.igem.org/mediawiki/2013/a/a8/PB_DetectNarrow.jpg" width="125px" height="500px"/> | ||
| + | <div class="titlebox"> | ||
| + | <center><img src="https://static.igem.org/mediawiki/2013/0/0b/PB_detecticon.gif" style="height:60px;margin-bottom:20px;"/></center> | ||
| + | <div style="width:60%;margin-left:20%;margin-bottom:20px;"><hr></div> | ||
| + | Detect | ||
| + | </div> | ||
| + | </div> | ||
| + | </a> | ||
| + | <a href="https://2013.igem.org/Team:Paris_Bettencourt/Project/Target" title="Target"> | ||
| + | <div id="dspanel" class="subpanel2"> | ||
| + | <img class="narrowimg" src="https://static.igem.org/mediawiki/2013/e/e2/PB_TargetNarrow.jpg" width="125px" height="500px"/> | ||
| + | <div class="titlebox"> | ||
| + | <center><img src="https://static.igem.org/mediawiki/2013/1/11/PB_TargetIcon.gif" style="height:60px;margin-bottom:20px;"/></center> | ||
| + | <div style="width:60%;margin-left:20%;margin-bottom:20px;"><hr></div> | ||
| + | Target | ||
| + | </div> | ||
| + | </div> | ||
| + | </a> | ||
| + | <a href="https://2013.igem.org/Team:Paris_Bettencourt/Project/Infiltrate" title="Infiltrate"> | ||
| + | <div id="tcpanel" class="subpanel2"> | ||
| + | <img class="narrowimg" src="https://static.igem.org/mediawiki/2013/2/21/PB_InfiltrateNarrow.jpg" width="125px" height="500px"/> | ||
| + | <div class="titlebox"> | ||
| + | <center><img src="https://static.igem.org/mediawiki/2013/6/6c/PB_infiltrate.gif" style="height:60px;margin-bottom:20px;"/></center> | ||
| + | <div style="width:60%;margin-left:20%;margin-bottom:20px;"><hr></div> | ||
| + | Infiltrate | ||
| + | </div> | ||
| + | </div> | ||
| + | </a> | ||
| + | <a href="https://2013.igem.org/Team:Paris_Bettencourt/Project/Sabotage" title="Sabotage"> | ||
| + | <div id="thpanel" class="subpanel2"> | ||
| + | <img class="narrowimg" src="https://static.igem.org/mediawiki/2013/4/42/PB_SabotageNarrow.jpg" width="125px" height="500px"/> | ||
| + | <div class="titlebox"> | ||
| + | <center><img src="https://static.igem.org/mediawiki/2013/8/81/PB_sabotageicone.gif" style="height:60px;margin-bottom:20px;"/></center> | ||
| + | <div style="width:60%;margin-left:20%;margin-bottom:20px;"><hr></div> | ||
| + | Sabotage | ||
| + | </div> | ||
| + | </div> | ||
| + | </a> | ||
| + | <a href="https://2013.igem.org/Team:Paris_Bettencourt/Results" title="Results"> | ||
| + | <div class="subpanel3" > | ||
| + | <img width="70px" style="margin-left:80px;margin-right:15px;position:relative;bottom:1px" src="https://static.igem.org/mediawiki/2013/d/d5/PB_handresults.gif"/>Jump to Results | ||
| + | </div> | ||
| + | </a> | ||
</div> | </div> | ||
| - | <div | + | <div style="clear: both;"></div> |
| - | <div class=" | + | <div class="panel" style="background:white;"> |
| - | < | + | <div class="subpanel4"> |
| + | <a href="https://2013.igem.org/Team:Paris_Bettencourt/Human_Practice/TB_Facts" title="TB Facts"> | ||
| + | <div class="subpanel5"> | ||
| + | <img class="narrowimg" src="https://static.igem.org/mediawiki/2013/f/f9/PB_TBfacts2.png" width="354px" height="156px"/> | ||
| + | <div style="position:relative;bottom:148px"> | ||
| + | <center><img src="https://static.igem.org/mediawiki/2013/6/69/PB_logoTBfacts.png" style="height:50px;margin-top:10px;margin-bottom:20px;"/></center> | ||
| + | <div style="width:60%;margin-left:20%;margin-bottom:20px;"><hr></div> | ||
| + | TB Facts | ||
| + | </div> | ||
| + | </div> | ||
| + | </a> | ||
| + | <a href="https://2013.igem.org/Team:Paris_Bettencourt/Human_Practice/TB_France" title="TB in France"> | ||
| + | <div class="subpanel5"> | ||
| + | <img class="narrowimg" src="https://static.igem.org/mediawiki/2013/3/39/PB_TBinFrance.png" width="354px" height="156px"/> | ||
| + | <div style="position:relative;bottom:158px"> | ||
| + | <center><img src="https://static.igem.org/mediawiki/2013/c/cf/PB_logofrance.png" style="height:50px;margin-top:10px;margin-bottom:20px;"/></center> | ||
| + | <div style="width:60%;margin-left:20%;margin-bottom:20px;"><hr></div> | ||
| + | TB in France | ||
| + | </div> | ||
| + | </div> | ||
| + | </a> | ||
| + | <a href="https://2013.igem.org/Team:Paris_Bettencourt/Human_Practice/TB_Gallery" title="TB Gallery"> | ||
| + | <div class="subpanel5" style="margin-bottom:0;height:158px;"> | ||
| + | <img class="narrowimg" src="https://static.igem.org/mediawiki/2013/2/2f/PB_TBgallery%281%29.png" width="354px" height="156px"/> | ||
| + | <div style="position:relative;bottom:158px"> | ||
| + | <center><img src="https://static.igem.org/mediawiki/2013/d/de/PB_logoTBgallery.png" style="height:60px;margin-top:10px;margin-bottom:10px;"/></center> | ||
| + | <div style="width:60%;margin-left:20%;margin-bottom:20px;"><hr></div> | ||
| + | TB Gallery | ||
| + | </div> | ||
| + | </div> | ||
| + | </a> | ||
</div> | </div> | ||
| - | + | <div class="subpanel4"> | |
| - | + | <a href="https://2013.igem.org/Team:Paris_Bettencourt/Human_Practice/Gender_Study" title="Gender Study"> | |
| - | + | <div class="subpanel7"> | |
| - | + | <img class="narrowimg" src="https://static.igem.org/mediawiki/2013/8/8c/Gender.png" width="354px" height="283px"/> | |
| - | + | <div style="position:relative;bottom:258px"> | |
| - | + | <center><img src="https://static.igem.org/mediawiki/2013/d/da/PB_logogender.png" style="height:60px;margin-top:10px;margin-bottom:10px;"/></center> | |
| - | + | <div style="width:60%;margin-left:20%;margin-bottom:20px;"><hr></div> | |
| - | + | Gender Study | |
| - | + | </div> | |
| + | </div> | ||
| + | </a> | ||
| + | <a href="https://2013.igem.org/Team:Paris_Bettencourt/Human_Practice/Technology_Transfer" title="Technology Transfer"> | ||
| + | <div class="subpanel9" style="font-size:26px;"> | ||
| + | <img class="narrowimg" src="https://static.igem.org/mediawiki/2013/3/3c/TB_knowledge.png" width="354px" height="283px"/> | ||
| + | <div style="position:relative;bottom:258px"> | ||
| + | <center><img src="https://static.igem.org/mediawiki/2013/6/6d/PB_logotransferttechno.png" style="height:60px;margin-top:10px;margin-bottom:10px;"/></center> | ||
| + | <div style="width:60%;margin-left:20%;margin-bottom:20px;"><hr></div> | ||
| + | Technology Transfer | ||
| + | </div> | ||
| + | </div> | ||
| + | </a> | ||
</div> | </div> | ||
| - | + | <div class="subpanel4" style="margin-right:0px"> | |
| - | + | <div style="margin-right:0;width:356px"> | |
| - | + | <a href="https://2013.igem.org/Team:Paris_Bettencourt/Collaboration" title="Collaboration"> | |
| - | + | <div class="subpanel6"> | |
| + | <img class="narrowimg" src="https://static.igem.org/mediawiki/2013/e/e4/TB_collboration2.png" width="354px" height="283px"/> | ||
| + | <div style="position:relative;bottom:258px"> | ||
| + | <center><img src="https://static.igem.org/mediawiki/2013/7/75/PB_lofocollaboration.png" style="height:50px;margin-top:15px;margin-bottom:15px;"/></center> | ||
| + | <div style="width:60%;margin-left:20%;margin-bottom:20px;"><hr></div> | ||
| + | Collaboration | ||
| + | </div> | ||
| + | </div> | ||
| + | </a> | ||
| + | <a href="https://2013.igem.org/Team:Paris_Bettencourt/SensiGEM" title="SensiGEM"> | ||
| + | <div class="subpanel6" style="margin-bottom:0"> | ||
| + | <img class="narrowimg" src="https://static.igem.org/mediawiki/2013/d/d5/TB_senigem.png" width="354px" height="283px"/> | ||
| + | <div style="position:relative;bottom:258px"> | ||
| + | <center><img src="https://static.igem.org/mediawiki/2013/3/3c/PB_logosenigem.png" style="height:60px;margin-top:10px;margin-bottom:10px;"/></center> | ||
| + | <div style="width:60%;margin-left:20%;margin-bottom:20px;"><hr></div> | ||
| + | SensiGEM | ||
| + | </div> | ||
| + | </div> | ||
| + | </a> | ||
| + | </div> | ||
</div> | </div> | ||
</div> | </div> | ||
| - | + | <div style="clear: both;"></div> | |
| - | + | <div> | |
| - | + | <div class="subpanel8"> | |
| - | + | <a href="https://2013.igem.org/Team:Paris_Bettencourt/Team" title="Team"> | |
| - | + | <center><img src="https://static.igem.org/mediawiki/2013/1/1c/PB_Teamlogo.png" height="64px"/></center> | |
| - | + | </a> | |
| - | + | ||
| - | + | ||
| - | + | ||
</div> | </div> | ||
| - | + | <div class="subpanel8"> | |
| - | + | <a href="https://2013.igem.org/Team:Paris_Bettencourt/Notes" title="Notebook"> | |
| - | + | <center><img src="https://static.igem.org/mediawiki/2013/2/27/PB_Notebooklogo.png" height="64px"/></center> | |
| - | + | </a> | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
</div> | </div> | ||
| - | + | <div class="subpanel8"> | |
| - | + | <a href="https://2013.igem.org/Team:Paris_Bettencourt/Parts" title="Submitted Parts"> | |
| - | + | <center><img src="https://static.igem.org/mediawiki/2013/0/02/PB_Partslogo.png" height="64px"/></center> | |
| - | + | </a> | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
</div> | </div> | ||
| - | + | <div class="subpanel8" style="margin-right:0"> | |
| - | + | <a href="https://2013.igem.org/Team:Paris_Bettencourt/Medal_Fulfillment" title="Medal Fulfillment"> | |
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Latest revision as of 14:06, 6 November 2013
FIGHT TUBERCULOSIS WITH MODERN WEAPONS
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (Mtb) that affects nearly two billion people around the world. On this website we present four new ways to use the power of synthetic biology in the fight against TB: from gene detection, to drug targeting, to infiltrating macrophages, to sabotaging the synthesis of proteins. Hover over these panels to see the project overview.
A biosensor that detects the presence of sequence specific antibiotic resistance genes.
A safe and specific high-throughput drug screening method that targets essential mycobacterial metabolic proteins.
A phage system with low fitness cost producing sRNA, which inhibits the synthesis of antibiotic resistance proteins.
Infiltrate macrophages with an E.coli producing TDMH, an enzyme that will lyse the Mycobacteria cell wall.
Jump to Results
Centre for Research and Interdisciplinarity (CRI)
Faculty of Medicine Cochin Port-Royal, South wing, 2nd floor
Paris Descartes University
24, rue du Faubourg Saint Jacques
75014 Paris, France
+33 1 44 41 25 22/25
team2013@igem-paris.org
+33 1 44 41 25 22/25
team2013@igem-paris.org 
