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Team:AMU-Poznan/Project
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| + | <h2>sh-miR Designer</h2> | ||
| + | <p>A tool for construction of sh-miRs - RNA interference reagents.</p> | ||
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| + | <li><a href="https://2013.igem.org/Team:AMU-Poznan">Home</a></li> | ||
| + | <li><a href="https://2013.igem.org/Team:AMU-Poznan/Team">Team</a></li> | ||
| + | <li><a href="https://2013.igem.org/Team:AMU-Poznan/Project">Project</a></li> | ||
| + | <li><a href="https://2013.igem.org/Team:AMU-Poznan/Medals">Medal requirements</a></li> | ||
| + | <li><a href="http://shmir.pl/" target="_blank">Our website</a></li> | ||
| + | <li><a href="http://github.com/igemsoftware/AMU-Poznan2013" target="_blank">Github</a></li> | ||
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| + | <h2>Overall project:</h2> | ||
| + | <h3>sh-miR designer: a tool for construction of sh-miRs - RNA interference reagents</h3> | ||
| + | <p> | ||
| + | sh-miR Designer is a piece of software, which will enable fast and efficient design of potentially effective RNA interference (RNAi) reagents – shmiRs, called also artificial miRNAs. sh-miRs are RNA particles whose structure is based on miRNA precursor pri-miRNA, but sequence interacting with transcript is changed depending on research purpose. Maintenance of structure of pri-miRNA is very important to enable cellular processing and therefore ensure functionality of artificial particles. Sh-miR designer algorithm includes structural features. sh-miRs delivered to cells on genetic vectors – plasmids or viral vectors - enter natural RNAi pathway and silence target mRNA. They can be used in genetic therapies and basic biomedical research.</p> | ||
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| + | <h2>Project Details</h2> | ||
| + | <ul> | ||
| + | <li><a href="http://shmir.pl" target="_blank">Official website</a></li> | ||
| + | <li><a href="http://shmir-designer.readthedocs.org/en/latest/_downloads/Documentation-1.pdf" target="_blank">Biological documentation</a></li> | ||
| + | <li><a href="http://shmir-designer.readthedocs.org/en/latest/" target="_blank">Program documentation</a></li> | ||
| + | <li><a href="http://shmir-designer.readthedocs.org/en/latest/_downloads/Documentation-2.pdf" target="_blank">Next version - plans</a></li> | ||
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Latest revision as of 19:10, 22 October 2013
sh-miR Designer
A tool for construction of sh-miRs - RNA interference reagents.
Overall project:
sh-miR designer: a tool for construction of sh-miRs - RNA interference reagents
sh-miR Designer is a piece of software, which will enable fast and efficient design of potentially effective RNA interference (RNAi) reagents – shmiRs, called also artificial miRNAs. sh-miRs are RNA particles whose structure is based on miRNA precursor pri-miRNA, but sequence interacting with transcript is changed depending on research purpose. Maintenance of structure of pri-miRNA is very important to enable cellular processing and therefore ensure functionality of artificial particles. Sh-miR designer algorithm includes structural features. sh-miRs delivered to cells on genetic vectors – plasmids or viral vectors - enter natural RNAi pathway and silence target mRNA. They can be used in genetic therapies and basic biomedical research.
