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Team:Paris Bettencourt/Project/Target/FBA
From 2013.igem.org
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<h2><i>E coli</i> essential genes</h2> | <h2><i>E coli</i> essential genes</h2> | ||
| - | + | <a href="http://www.ecocyc.org/overviewsWeb/celOv.shtml?zoomlevel=0&lon=600&lat=29765&orgid=ECOLI&gnids=cysZ,purD,gmk,tyrA,dapE,sbp,leuD,hisH,trpE,ilvM,murE,rpiA,leuB,trpC,thrA,cysU,murF,tyrB,accB,argB,pyrE,lysA,metL,metC,hisC,glmU,guaB,hisG,ydiB,cynT,metE,hisI,fabB,accD,lysC,dapD,thyA,purL,cysH,folA,yqaB,purB,cysP,mraY,murI,ilvE,ilvG_2,cysM,ilvC,fabZ,serC,metH,purH,aroH,aroL,argI,dapA,serB,metB,cysE,aroD,hisB,dapF,aroF,trxB,pheA,ddlB,fabG,purA,murB,aroB,accC,pyrF,murA,dapB,metK,puuA,ilvI,trpD,fabD,ilvH,ilvB,murG,purF,ndk,murD,aroK,pyrB,cysA,argD,ilvN,fabF,ilvG_1,purM,prs,cysW,argC,pyrI,rpiB,accA,cysC,hisD,argF,ilvD,fabA,aroG,malY,glmS,murC,leuA,purC,glnA,can,cysK,fabI,serA,hisF,ppa,guaA,pgm,ddlA,leuC,aroC,pyrC,aroE,asd,aspC,hisA,aroA" target="_blank"><img src="https://static.igem.org/mediawiki/2013/2/21/PB_EcoCyc_Essential.png" width="100%" /></a> | |
| - | + | ||
| - | + | ||
<h2>List of predicted complementary knockouts</h2> | <h2>List of predicted complementary knockouts</h2> | ||
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<td>cysK cysM </td> | <td>cysK cysM </td> | ||
<td><a href="http://www.ecocyc.org/overviewsWeb/celOv.shtml?zoomlevel=0&lon=600&lat=29765&orgid=ECOLI&gnids=cysK,cysM" target="_blank">browse</a></td> | <td><a href="http://www.ecocyc.org/overviewsWeb/celOv.shtml?zoomlevel=0&lon=600&lat=29765&orgid=ECOLI&gnids=cysK,cysM" target="_blank">browse</a></td> | ||
| - | <td>cysteine biosynthesis | + | <td>cysteine biosynthesis </td> |
</tr> | </tr> | ||
<tr> | <tr> | ||
| Line 289: | Line 287: | ||
<td>gmk </td> | <td>gmk </td> | ||
<td><a href="http://www.ecocyc.org/overviewsWeb/celOv.shtml?zoomlevel=0&lon=600&lat=29765&orgid=ECOLI&gnids=gmk" target="_blank">browse</a></td> | <td><a href="http://www.ecocyc.org/overviewsWeb/celOv.shtml?zoomlevel=0&lon=600&lat=29765&orgid=ECOLI&gnids=gmk" target="_blank">browse</a></td> | ||
| - | <td> | + | <td>purine nucleotide biosynthesis</td> |
</tr> | </tr> | ||
<tr> | <tr> | ||
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<td>puuA glnA </td> | <td>puuA glnA </td> | ||
<td><a href="http://www.ecocyc.org/overviewsWeb/celOv.shtml?zoomlevel=0&lon=600&lat=29765&orgid=ECOLI&gnids=puuA,glnA" target="_blank">browse</a></td> | <td><a href="http://www.ecocyc.org/overviewsWeb/celOv.shtml?zoomlevel=0&lon=600&lat=29765&orgid=ECOLI&gnids=puuA,glnA" target="_blank">browse</a></td> | ||
| - | <td>putrescine | + | <td>putrescine catabolism</td> |
</tr> | </tr> | ||
<tr> | <tr> | ||
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<td>|can| cynT </td> | <td>|can| cynT </td> | ||
<td><a href="http://www.ecocyc.org/overviewsWeb/celOv.shtml?zoomlevel=0&lon=600&lat=29765&orgid=ECOLI&gnids=|can|,cynT" target="_blank">browse</a></td> | <td><a href="http://www.ecocyc.org/overviewsWeb/celOv.shtml?zoomlevel=0&lon=600&lat=29765&orgid=ECOLI&gnids=|can|,cynT" target="_blank">browse</a></td> | ||
| - | <td>cyanate | + | <td>cyanate catabolism</td> |
</tr> | </tr> | ||
<tr> | <tr> | ||
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<td>purH </td> | <td>purH </td> | ||
<td><a href="http://www.ecocyc.org/overviewsWeb/celOv.shtml?zoomlevel=0&lon=600&lat=29765&orgid=ECOLI&gnids=purH" target="_blank">browse</a></td> | <td><a href="http://www.ecocyc.org/overviewsWeb/celOv.shtml?zoomlevel=0&lon=600&lat=29765&orgid=ECOLI&gnids=purH" target="_blank">browse</a></td> | ||
| - | <td> | + | <td>purine nucleotide biosynthesis</td> |
</tr> | </tr> | ||
<tr> | <tr> | ||
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<td>guaB </td> | <td>guaB </td> | ||
<td><a href="http://www.ecocyc.org/overviewsWeb/celOv.shtml?zoomlevel=0&lon=600&lat=29765&orgid=ECOLI&gnids=guaB" target="_blank">browse</a></td> | <td><a href="http://www.ecocyc.org/overviewsWeb/celOv.shtml?zoomlevel=0&lon=600&lat=29765&orgid=ECOLI&gnids=guaB" target="_blank">browse</a></td> | ||
| - | <td> | + | <td>purine nucleotide biosynthesis</td> |
</tr> | </tr> | ||
<tr> | <tr> | ||
| Line 457: | Line 455: | ||
<td>ndk </td> | <td>ndk </td> | ||
<td><a href="http://www.ecocyc.org/overviewsWeb/celOv.shtml?zoomlevel=0&lon=600&lat=29765&orgid=ECOLI&gnids=ndk" target="_blank">browse</a></td> | <td><a href="http://www.ecocyc.org/overviewsWeb/celOv.shtml?zoomlevel=0&lon=600&lat=29765&orgid=ECOLI&gnids=ndk" target="_blank">browse</a></td> | ||
| - | <td> | + | <td>purine nucleotide biosynthesis</td> |
</tr> | </tr> | ||
<tr> | <tr> | ||
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<td>ndk </td> | <td>ndk </td> | ||
<td><a href="http://www.ecocyc.org/overviewsWeb/celOv.shtml?zoomlevel=0&lon=600&lat=29765&orgid=ECOLI&gnids=ndk" target="_blank">browse</a></td> | <td><a href="http://www.ecocyc.org/overviewsWeb/celOv.shtml?zoomlevel=0&lon=600&lat=29765&orgid=ECOLI&gnids=ndk" target="_blank">browse</a></td> | ||
| - | <td> | + | <td>purine nucleotide biosynthesis</td> |
</tr> | </tr> | ||
<tr> | <tr> | ||
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<td>pyrF </td> | <td>pyrF </td> | ||
<td><a href="http://www.ecocyc.org/overviewsWeb/celOv.shtml?zoomlevel=0&lon=600&lat=29765&orgid=ECOLI&gnids=pyrF" target="_blank">browse</a></td> | <td><a href="http://www.ecocyc.org/overviewsWeb/celOv.shtml?zoomlevel=0&lon=600&lat=29765&orgid=ECOLI&gnids=pyrF" target="_blank">browse</a></td> | ||
| - | <td> | + | <td>purine nucleotide biosynthesis</td> |
</tr> | </tr> | ||
<tr> | <tr> | ||
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<td>cysH </td> | <td>cysH </td> | ||
<td><a href="http://www.ecocyc.org/overviewsWeb/celOv.shtml?zoomlevel=0&lon=600&lat=29765&orgid=ECOLI&gnids=cysH" target="_blank">browse</a></td> | <td><a href="http://www.ecocyc.org/overviewsWeb/celOv.shtml?zoomlevel=0&lon=600&lat=29765&orgid=ECOLI&gnids=cysH" target="_blank">browse</a></td> | ||
| - | <td>sulfur compound | + | <td>sulfur compound metabolism</td> |
</tr> | </tr> | ||
<tr> | <tr> | ||
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<td>pgm yqaB </td> | <td>pgm yqaB </td> | ||
<td><a href="http://www.ecocyc.org/overviewsWeb/celOv.shtml?zoomlevel=0&lon=600&lat=29765&orgid=ECOLI&gnids=pgm,yqaB" target="_blank">browse</a></td> | <td><a href="http://www.ecocyc.org/overviewsWeb/celOv.shtml?zoomlevel=0&lon=600&lat=29765&orgid=ECOLI&gnids=pgm,yqaB" target="_blank">browse</a></td> | ||
| - | <td>glucose | + | <td>glucose metabolism</td> |
</tr> | </tr> | ||
<tr> | <tr> | ||
| Line 520: | Line 518: | ||
<td>ppa </td> | <td>ppa </td> | ||
<td><a href="http://www.ecocyc.org/overviewsWeb/celOv.shtml?zoomlevel=0&lon=600&lat=29765&orgid=ECOLI&gnids=ppa" target="_blank">browse</a></td> | <td><a href="http://www.ecocyc.org/overviewsWeb/celOv.shtml?zoomlevel=0&lon=600&lat=29765&orgid=ECOLI&gnids=ppa" target="_blank">browse</a></td> | ||
| - | <td>phosphate-containing compound | + | <td>phosphate-containing compound metabolism</td> |
</tr> | </tr> | ||
<tr> | <tr> | ||
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<td>rpiA rpiB </td> | <td>rpiA rpiB </td> | ||
<td><a href="http://www.ecocyc.org/overviewsWeb/celOv.shtml?zoomlevel=0&lon=600&lat=29765&orgid=ECOLI&gnids=rpiA,rpiB" target="_blank">browse</a></td> | <td><a href="http://www.ecocyc.org/overviewsWeb/celOv.shtml?zoomlevel=0&lon=600&lat=29765&orgid=ECOLI&gnids=rpiA,rpiB" target="_blank">browse</a></td> | ||
| - | <td>D-ribose | + | <td>D-ribose metabolism</td> |
</tr> | </tr> | ||
<tr> | <tr> | ||
| Line 639: | Line 637: | ||
<td>cysE </td> | <td>cysE </td> | ||
<td><a href="http://www.ecocyc.org/overviewsWeb/celOv.shtml?zoomlevel=0&lon=600&lat=29765&orgid=ECOLI&gnids=cysE" target="_blank">browse</a></td> | <td><a href="http://www.ecocyc.org/overviewsWeb/celOv.shtml?zoomlevel=0&lon=600&lat=29765&orgid=ECOLI&gnids=cysE" target="_blank">browse</a></td> | ||
| - | <td>cysteine biosynthesis | + | <td>cysteine biosynthesis </td> |
</tr> | </tr> | ||
<tr> | <tr> | ||
| Line 667: | Line 665: | ||
<td>cysZ cysA cysW cysU cysP sbp </td> | <td>cysZ cysA cysW cysU cysP sbp </td> | ||
<td><a href="http://www.ecocyc.org/overviewsWeb/celOv.shtml?zoomlevel=0&lon=600&lat=29765&orgid=ECOLI&gnids=cysZ,cysA,cysW,cysU,cysP,sbp" target="_blank">browse</a></td> | <td><a href="http://www.ecocyc.org/overviewsWeb/celOv.shtml?zoomlevel=0&lon=600&lat=29765&orgid=ECOLI&gnids=cysZ,cysA,cysW,cysU,cysP,sbp" target="_blank">browse</a></td> | ||
| - | <td>sulfur compound | + | <td>sulfur compound metabolism</td> |
</tr> | </tr> | ||
<tr> | <tr> | ||
Latest revision as of 14:29, 28 October 2013
E coli essential genes
List of predicted complementary knockouts
| M Tuberculosis essential gene(s) | BioCyc Link | E coli knockout(s) | BioCyc Link | Cellular Process |
|---|---|---|---|---|
| accD3 accD5 Rv3281 | browse | accA accD accB accC | browse | fatty acid biosynthesis |
| argB | browse | argB | browse | arginine biosynthesis |
| ilvG ilvN ilvB ilvB2 ilvX | browse | ilvI ilvH ilvN ilvB ilvG_1 ilvG_2 ilvM | browse | valine biosynthesis |
| argD | browse | argD | browse | arginine biosynthesis |
| cysD cysN | browse | cysC | browse | phosphorylation |
| purB | browse | purB | browse | purine nucleotide biosynthesis |
| purB | browse | purB | browse | purine nucleotide biosynthesis |
| purA | browse | purA | browse | purine nucleotide biosynthesis |
| argC | browse | argC | browse | arginine biosynthesis |
| ddlA | browse | ddlB ddlA | browse | peptidoglycan biosynthesis |
| trpD | browse | trpD | browse | tryptophan biosynthesis |
| trpE Rv2859c | browse | trpD trpE | browse | tryptophan biosynthesis |
| asd | browse | asd | browse | homoserine biosynthesis |
| pyrB | browse | pyrI pyrB | browse | pyrimidine nucleotide biosynthesis |
| ask | browse | thrA metL lysC | browse | homoserine biosynthesis |
| aspC aspB | browse | aspC | browse | L-phenylalanine biosynthesis |
| hisG | browse | hisG | browse | histidine biosynthesis |
| fabG2 inhA fas pks15 | browse | fabZ fabA fabG fabF fabI fabB | browse | fatty acid biosynthesis |
| Rv1885c | browse | pheA tyrA | browse | L-phenylalanine biosynthesis |
| aroF | browse | aroC | browse | chorismate biosynthesis |
| cysM3 cysM cysK | browse | cysK cysM | browse | cysteine biosynthesis |
| metC | browse | malY metC | browse | transcription, DNA-dependent |
| lysA | browse | lysA | browse | cellular amino acid biosynthesis |
| dapF | browse | dapF | browse | cellular amino acid biosynthesis |
| aroG | browse | aroG aroH aroF | browse | L-phenylalanine biosynthesis |
| ilvD | browse | ilvD | browse | valine biosynthesis |
| dapB | browse | dapB | browse | diaminopimelate biosynthesis |
| dapA | browse | dapA | browse | diaminopimelate biosynthesis |
| dfrA | browse | folA | browse | 10-formyltetrahydrofolate biosynthesis |
| pyrC | browse | pyrC | browse | pyrimidine nucleotide biosynthesis |
| aroD | browse | aroD | browse | chorismate biosynthesis |
| aroB | browse | aroB | browse | chorismate biosynthesis |
| glmU | browse | glmU | browse | UDP-N-acetylglucosamine biosynthesis |
| glmS | browse | glmS | browse | UDP-N-acetylglucosamine biosynthesis |
| gmk | browse | gmk | browse | purine nucleotide biosynthesis |
| glnA3 glnA glnA1 glnA2 glnA4 | browse | puuA glnA | browse | putrescine catabolism |
| purF hisH | browse | purF | browse | purine nucleotide biosynthesis |
| murI | browse | murI | browse | peptidoglycan biosynthesis |
| guaA | browse | guaA | browse | GMP biosynthesis |
| Rv3273 Rv3588c | browse | |can| cynT | browse | cyanate catabolism |
| hisD | browse | hisD | browse | histidine biosynthesis |
| hisC cobC hisC2 | browse | hisC | browse | histidine biosynthesis |
| hisF | browse | hisH hisF | browse | histidine biosynthesis |
| hisB | browse | hisB | browse | histidine biosynthesis |
| trpC | browse | trpC | browse | tryptophan biosynthesis |
| ilvE | browse | ilvE | browse | valine biosynthesis |
| purH | browse | purH | browse | purine nucleotide biosynthesis |
| guaB1 guaB3 guaB2 | browse | guaB | browse | purine nucleotide biosynthesis |
| leuB | browse | leuB | browse | leucine biosynthesis |
| leuD leuC | browse | leuD leuC | browse | leucine biosynthesis |
| leuD leuC | browse | leuD leuC | browse | leucine biosynthesis |
| leuA | browse | leuA | browse | leucine biosynthesis |
| ilvC | browse | ilvC | browse | valine biosynthesis |
| ilvC | browse | ilvC | browse | valine biosynthesis |
| ilvE | browse | ilvE tyrB | browse | valine biosynthesis |
| fadD37 fabD | browse | fabD | browse | fatty acid biosynthesis |
| metK | browse | metK | browse | S-adenosylmethionine biosynthesis |
| metH | browse | metE metH | browse | methionine biosynthesis |
| ndkA | browse | ndk | browse | purine nucleotide biosynthesis |
| ndkA | browse | ndk | browse | purine nucleotide biosynthesis |
| argF | browse | argF argI | browse | arginine biosynthesis |
| pyrF | browse | pyrF | browse | purine nucleotide biosynthesis |
| umpA | browse | pyrE | browse | pyrimidine nucleotide biosynthesis |
| murX | browse | mraY | browse | peptidoglycan biosynthesis |
| cysH | browse | cysH | browse | sulfur compound metabolism |
| Rv0728c serA | browse | serA | browse | L-serine biosynthesis |
| pgmA | browse | pgm yqaB | browse | glucose metabolism |
| ppa | browse | ppa | browse | phosphate-containing compound metabolism |
| tyrA | browse | tyrA | browse | L-phenylalanine biosynthesis |
| pheA | browse | pheA | browse | L-phenylalanine biosynthesis |
| purD | browse | purD | browse | purine nucleotide biosynthesis |
| purM | browse | purM | browse | purine nucleotide biosynthesis |
| hisA | browse | trpC | browse | tryptophan biosynthesis |
| hisI2 | browse | hisI | browse | histidine biosynthesis |
| purC | browse | purC | browse | purine nucleotide biosynthesis |
| hisI | browse | hisI | browse | histidine biosynthesis |
| purQ purL | browse | purL | browse | purine nucleotide biosynthesis |
| hisA | browse | hisA | browse | histidine biosynthesis |
| prsA | browse | prs | browse | nucleotide biosynthesis |
| aroA | browse | aroA | browse | chorismate biosynthesis |
| serC | browse | serC | browse | L-serine biosynthesis |
| serB serB2 | browse | serB | browse | L-serine biosynthesis |
| rpi | browse | rpiA rpiB | browse | D-ribose metabolism |
| dapE | browse | dapE | browse | cellular amino acid biosynthesis |
| cysE | browse | cysE | browse | cysteine biosynthesis |
| aroE | browse | ydiB aroE | browse | chorismate biosynthesis |
| aroK | browse | aroL aroK | browse | chorismate biosynthesis |
| metZ metB | browse | metB | browse | methionine biosynthesis |
| Rv1739c cysA cysW cysT subI | browse | cysZ cysA cysW cysU cysP sbp | browse | sulfur compound metabolism |
| Rv1201c | browse | dapD | browse | lysine biosynthesis |
| Rv2754c thyA | browse | thyA | browse | 10-formyltetrahydrofolate biosynthesis |
| trxB2 | browse | trxB | browse | oxidation-reduction process |
| murE | browse | murE | browse | peptidoglycan biosynthesis |
| murA | browse | murA | browse | peptidoglycan biosynthesis |
| glmU | browse | glmU | browse | UDP-N-acetylglucosamine biosynthesis |
| murG | browse | murG | browse | peptidoglycan biosynthesis |
| murD | browse | murD | browse | peptidoglycan biosynthesis |
| murC | browse | murC | browse | peptidoglycan biosynthesis |
| murB | browse | murB | browse | peptidoglycan biosynthesis |
| murF | browse | murF | browse | peptidoglycan biosynthesis |
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