Team:AMU-Poznan/Project

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<title>sh-miR Designer</title>
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You are provided with this team page template with which to start the iGEM season.  You may choose to personalize it to fit your team but keep the same "look." Or you may choose to take your team wiki to a different level and design your own wiki.  You can find some examples <a href="https://2008.igem.org/Help:Template/Examples">HERE</a>.
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!align="center"|[[Team:AMU-Poznan|Home]]
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            <h2>sh-miR Designer</h2>
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!align="center"|[[Team:AMU-Poznan/Team|Team]]
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            <p>A tool for construction of sh-miRs - RNA interference reagents.</p>
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!align="center"|[https://igem.org/Team.cgi?year=2013&team_name=AMU-Poznan Official Team Profile]
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!align="center"|[[Team:AMU-Poznan/Project|Project]]
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!align="center"|[[Team:AMU-Poznan/Parts|Parts Submitted to the Registry]]
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!align="center"|[[Team:AMU-Poznan/Modeling|Modeling]]
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!align="center"|[[Team:AMU-Poznan/Notebook|Notebook]]
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!align="center"|[[Team:AMU-Poznan/Safety|Safety]]
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!align="center"|[[Team:AMU-Poznan/Attributions|Attributions]]
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          <li><a href="https://2013.igem.org/Team:AMU-Poznan">Home</a></li>
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          <li><a href="https://2013.igem.org/Team:AMU-Poznan/Team">Team</a></li>
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          <li><a href="https://2013.igem.org/Team:AMU-Poznan/Project">Project</a></li>
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          <li><a href="https://2013.igem.org/Team:AMU-Poznan/Medals">Medal requirements</a></li>
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          <li><a href="http://shmir.pl/" target="_blank">Our website</a></li>
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          <li><a href="http://github.com/igemsoftware/AMU-Poznan2013" target="_blank">Github</a></li>
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<h2>Overall project:</h2>
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<h3>sh-miR designer: a tool for construction of sh-miRs - RNA interference reagents</h3>
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<p>
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sh-miR Designer is a piece of software, which will enable fast and efficient design of potentially effective RNA interference (RNAi) reagents – shmiRs, called also artificial miRNAs. sh-miRs are RNA particles whose structure is based on miRNA precursor pri-miRNA, but sequence interacting with transcript is changed depending on research purpose. Maintenance of structure of pri-miRNA is very important to enable cellular processing and therefore ensure functionality of artificial particles. Sh-miR designer algorithm includes structural features. sh-miRs delivered to cells on genetic vectors – plasmids or viral vectors - enter natural RNAi pathway and silence target mRNA. They can be used in genetic therapies and basic biomedical research.</p>
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<h2>Project Details</h2>
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<li><a href="http://shmir.pl" target="_blank">Official website</a></li>
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<li><a href="http://shmir-designer.readthedocs.org/en/latest/_downloads/Documentation-1.pdf" target="_blank">Biological documentation</a></li>
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<li><a href="http://shmir-designer.readthedocs.org/en/latest/" target="_blank">Program documentation</a></li>
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<li><a href="http://shmir-designer.readthedocs.org/en/latest/_downloads/Documentation-2.pdf" target="_blank">Next version - plans</a></li>
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== '''Overall project''' ==
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'''sh-miR designer: a tool for construction of sh-miRs - RNA interference reagents'''
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sh-miR Designer is a piece of software, which will enable fast and efficient design of potentially effective RNA interference (RNAi) reagents – shmiRs, called also artificial miRNAs. sh-miRs are RNA particles whose structure is based on miRNA precursor pri-miRNA, but sequence interacting with transcript is changed depending on research purpose. Maintenance of structure of pri-miRNA is very important to enable cellular processing and therefore ensure functionality of artificial particles. Sh-miR designer algorithm includes structural features. sh-miRs delivered to cells on genetic vectors – plasmids or viral vectors - enter natural RNAi pathway and silence target mRNA. They can be used in genetic therapies and basic biomedical research.
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== Project Details==
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=== Part 2 ===
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=== The Experiments ===
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=== Part 3 ===
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== Results ==
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Latest revision as of 19:10, 22 October 2013

sh-miR Designer

sh-miR Designer

A tool for construction of sh-miRs - RNA interference reagents.

Overall project:

sh-miR designer: a tool for construction of sh-miRs - RNA interference reagents

sh-miR Designer is a piece of software, which will enable fast and efficient design of potentially effective RNA interference (RNAi) reagents – shmiRs, called also artificial miRNAs. sh-miRs are RNA particles whose structure is based on miRNA precursor pri-miRNA, but sequence interacting with transcript is changed depending on research purpose. Maintenance of structure of pri-miRNA is very important to enable cellular processing and therefore ensure functionality of artificial particles. Sh-miR designer algorithm includes structural features. sh-miRs delivered to cells on genetic vectors – plasmids or viral vectors - enter natural RNAi pathway and silence target mRNA. They can be used in genetic therapies and basic biomedical research.