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Team:AMU-Poznan/Project
From 2013.igem.org
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<h2>Project Details</h2> | <h2>Project Details</h2> | ||
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| - | <li><a href="http://shmir.pl">Official website</a></li> | + | <li><a href="http://shmir.pl" target="_blank">Official website</a></li> |
<li><a href="http://shmir-designer.readthedocs.org/en/latest/_downloads/Documentation-1.pdf" target="_blank">Biological documentation</a></li> | <li><a href="http://shmir-designer.readthedocs.org/en/latest/_downloads/Documentation-1.pdf" target="_blank">Biological documentation</a></li> | ||
<li><a href="http://shmir-designer.readthedocs.org/en/latest/" target="_blank">Program documentation</a></li> | <li><a href="http://shmir-designer.readthedocs.org/en/latest/" target="_blank">Program documentation</a></li> | ||
Revision as of 18:00, 22 October 2013
sh-miR Designer
A tool for construction of sh-miRs - RNA interference reagents.
Overall project:
sh-miR designer: a tool for construction of sh-miRs - RNA interference reagents
sh-miR Designer is a piece of software, which will enable fast and efficient design of potentially effective RNA interference (RNAi) reagents – shmiRs, called also artificial miRNAs. sh-miRs are RNA particles whose structure is based on miRNA precursor pri-miRNA, but sequence interacting with transcript is changed depending on research purpose. Maintenance of structure of pri-miRNA is very important to enable cellular processing and therefore ensure functionality of artificial particles. Sh-miR designer algorithm includes structural features. sh-miRs delivered to cells on genetic vectors – plasmids or viral vectors - enter natural RNAi pathway and silence target mRNA. They can be used in genetic therapies and basic biomedical research.
