Team:AMU-Poznan/Project

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<title>sh-miR Designer</title>
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!align="center"|[[Team:AMU-Poznan|Home]]
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            <h2>sh-miR Designer</h2>
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!align="center"|[[Team:AMU-Poznan/Team|Team]]
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            <p>A tool for construction of sh-miRs - RNA interference reagents.</p>
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!align="center"|[https://igem.org/Team.cgi?year=2013&team_name=AMU-Poznan Official Team Profile]
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!align="center"|[[Team:AMU-Poznan/Project|Project]]
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!align="center"|[[Team:AMU-Poznan/Parts|Parts Submitted to the Registry]]
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!align="center"|[[Team:AMU-Poznan/Modeling|Modeling]]
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!align="center"|[[Team:AMU-Poznan/Notebook|Notebook]]
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!align="center"|[[Team:AMU-Poznan/Safety|Safety]]
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!align="center"|[[Team:AMU-Poznan/Attributions|Attributions]]
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          <li><a href="https://2013.igem.org/Team:AMU-Poznan">Home</a></li>
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          <li><a href="https://2013.igem.org/Team:AMU-Poznan/Team">Team</a></li>
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          <li><a href="https://2013.igem.org/Team:AMU-Poznan/Project">Project</a></li>
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          <li><a href="https://github.com/igemsoftware/AMU-Poznan2013" target="_blank">Github</a></li>
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<h2>Overall project:</h2>
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<h3>sh-miR designer: a tool for construction of sh-miRs - RNA interference reagents</h3>
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<p>
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sh-miR Designer is a piece of software, which will enable fast and efficient design of potentially effective RNA interference (RNAi) reagents – shmiRs, called also artificial miRNAs. sh-miRs are RNA particles whose structure is based on miRNA precursor pri-miRNA, but sequence interacting with transcript is changed depending on research purpose. Maintenance of structure of pri-miRNA is very important to enable cellular processing and therefore ensure functionality of artificial particles. Sh-miR designer algorithm includes structural features. sh-miRs delivered to cells on genetic vectors – plasmids or viral vectors - enter natural RNAi pathway and silence target mRNA. They can be used in genetic therapies and basic biomedical research.</p>
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<h2>Project Details</h2>
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<li><a href="http://shmir.pl">Official website</a></li>
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<li><a href="http://shmir-designer.readthedocs.org/en/latest/_downloads/Documentation-1.pdf">Biological documentation</a></li>
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<li><a href="http://shmir-designer.readthedocs.org/en/latest/">Program documentation</a></li>
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<li><a href="http://shmir-designer.readthedocs.org/en/latest/_downloads/Documentation-2.pdf">Next version - plans</a></li>
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== '''Overall project''' ==
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'''sh-miR designer: a tool for construction of sh-miRs - RNA interference reagents'''
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sh-miR Designer is a piece of software, which will enable fast and efficient design of potentially effective RNA interference (RNAi) reagents – shmiRs, called also artificial miRNAs. sh-miRs are RNA particles whose structure is based on miRNA precursor pri-miRNA, but sequence interacting with transcript is changed depending on research purpose. Maintenance of structure of pri-miRNA is very important to enable cellular processing and therefore ensure functionality of artificial particles. Sh-miR designer algorithm includes structural features. sh-miRs delivered to cells on genetic vectors – plasmids or viral vectors - enter natural RNAi pathway and silence target mRNA. They can be used in genetic therapies and basic biomedical research.
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== Project Details==
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=== Part 2 ===
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=== The Experiments ===
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=== Part 3 ===
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== Results ==
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Revision as of 17:21, 22 October 2013

sh-miR Designer

sh-miR Designer

A tool for construction of sh-miRs - RNA interference reagents.

Overall project:

sh-miR designer: a tool for construction of sh-miRs - RNA interference reagents

sh-miR Designer is a piece of software, which will enable fast and efficient design of potentially effective RNA interference (RNAi) reagents – shmiRs, called also artificial miRNAs. sh-miRs are RNA particles whose structure is based on miRNA precursor pri-miRNA, but sequence interacting with transcript is changed depending on research purpose. Maintenance of structure of pri-miRNA is very important to enable cellular processing and therefore ensure functionality of artificial particles. Sh-miR designer algorithm includes structural features. sh-miRs delivered to cells on genetic vectors – plasmids or viral vectors - enter natural RNAi pathway and silence target mRNA. They can be used in genetic therapies and basic biomedical research.

Project Details

Retrieved from "http://2013.igem.org/Team:AMU-Poznan/Project"