Team:Imperial College/Waste Cocktail/Modelling

From 2013.igem.org

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<h2>Ordinary differential equations (ODEs)</h2>
<h2>Ordinary differential equations (ODEs)</h2>
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The system is controlled by using inducible promoters for the gene expression. In our degradation model, we used Hill expression to represent either the repression and induction by the transcription factors on the promoters
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The system is controlled by inducible promoters for the gene expression. In our degradation model, we used Hill equation to represent either the repression and induction by the transcription factors on the promoters

Latest revision as of 10:06, 27 August 2013

Contents

Polyurethane Degradation

Ordinary differential equations (ODEs)

The system is controlled by inducible promoters for the gene expression. In our degradation model, we used Hill equation to represent either the repression and induction by the transcription factors on the promoters


Michaelis-Menten kinetics

Enzyme kinetics can be described by 4 ODEs. However, it is impossible to measure [ES] experimentally and that means the ODEs have to be simplified for modelling. Michaelis-Menten kinetics assumes quasi-stationary approximation to solve this problem.

Matlab Simbiology

Simbiology is an extension of Matlab that we used to build and simulate our models. It allows modelling in graphical and programmable environments and uses in-built ODE solvers to simulate the time profile of species levels involved in the model.
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