Team:Tokyo Tech

From 2013.igem.org

(Difference between revisions)
Line 5: Line 5:
<div class=textspace>
<div class=textspace>
<div class="#66FFFF">
<div class="#66FFFF">
-
<h1>Abstract</h1><h2>Food shortages are said to be inevitable due to rapid population growth. Previous iGEM teams have approached to solve the problem by challenging to express plant hormone in E.Coli (2010 imperial college, 2012 Evry, 2012 Kyoto).
+
<h1>Abstract</h1><h2>
 +
‘Mutant Ninja.coli’ (A play on ‘Teenage Mutant Ninja Turtles’)
<br>
<br>
<br>
<br>
-
Our goal is to make progress with transforming E. Coli to act upon plants. That is to say, we aim to create “Farmer E. Coli”, which senses the nutrition of soil and expresses the plant hormones properly. We need to synthesize auxin, which is presented by Imperial College in 2010 iGEM, and cytokinin on our own.
+
In our project, we propose to create E. coli that mimic some of the qualities of Japan’s ancient ‘ninja’ warrior-spies.
<br>
<br>
 +
A ninja must receive and pass on correct information at all times. A mistake will be fatal. We have created a circuit that avoids crosstalk between two signals in cell-cell communication, and we are also looking into applications for it.
<br>
<br>
-
We will find the solution of “Safety” and “Crosstalk” problems considered when we put this to practical use. As to safety, we plan to create E. Coli which destroys external E. Coli by genome transportation of phage. Furthermore, we will design a new circuit to circumvent the crosstalk. </h2>
+
<br>
 +
Ninjas are also known for their ‘shuriken’ throwing knives. Our E. coli ninja has a similar weapon, an M13 phage which it releases to infect other E. coli, injecting plasmid DNA into them.  
 +
<br>
 +
<br>
 +
Finally, ninja must harmonize with the natural environment, so their relationship to it is very important. Plant hormones help plants to grow efficiently, and we are attempting to construct a circuit that synthesizes two plant hormones depending on the soil environment. </h2>
</div>
</div>
<table class="projecttable">
<table class="projecttable">

Revision as of 12:44, 4 September 2013

Abstract

‘Mutant Ninja.coli’ (A play on ‘Teenage Mutant Ninja Turtles’)

In our project, we propose to create E. coli that mimic some of the qualities of Japan’s ancient ‘ninja’ warrior-spies.
A ninja must receive and pass on correct information at all times. A mistake will be fatal. We have created a circuit that avoids crosstalk between two signals in cell-cell communication, and we are also looking into applications for it.

Ninjas are also known for their ‘shuriken’ throwing knives. Our E. coli ninja has a similar weapon, an M13 phage which it releases to infect other E. coli, injecting plasmid DNA into them.

Finally, ninja must harmonize with the natural environment, so their relationship to it is very important. Plant hormones help plants to grow efficiently, and we are attempting to construct a circuit that synthesizes two plant hormones depending on the soil environment.

Retrieved from "http://2013.igem.org/Team:Tokyo_Tech"