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Team:Peking
From 2013.igem.org
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| - | <p id="AbstractContent"> | + | <p id="AbstractContent">Monitoring aromatics in the environment remains a substantial challenge today. Noting the power of biosensors to enable quick and convenient testing, Peking iGEM have developed a functionally comprehensive biosensor toolkit to profile aromatics in the environment. |
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Transcriptional regulators that each senses a specific class of aromatics were first bioinformatically determined; they were then utilized to build a comprehensive set of biosensor circuits. Characterization on the detection profiles of individual biosensors and their orthogonality/crosstalk prove that these biosensors are really high-performance to profile aromatics in water. | Transcriptional regulators that each senses a specific class of aromatics were first bioinformatically determined; they were then utilized to build a comprehensive set of biosensor circuits. Characterization on the detection profiles of individual biosensors and their orthogonality/crosstalk prove that these biosensors are really high-performance to profile aromatics in water. | ||
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Moreover, for the ease of practical applications, two types of genetic devices were also developed as plug-ins for biosensors: "Adaptors", a set of conceptually novel devices to convert undetectable chemicals into detectable aromatics, and "Band-pass Filter", a "concentration filter" that allows the detection of analyte concentration within a specific range. | Moreover, for the ease of practical applications, two types of genetic devices were also developed as plug-ins for biosensors: "Adaptors", a set of conceptually novel devices to convert undetectable chemicals into detectable aromatics, and "Band-pass Filter", a "concentration filter" that allows the detection of analyte concentration within a specific range. | ||
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| + | We expect that these novel biosensors, together with the Adaptors and the Band-pass Filter, will serve as intriguing synthetic biological tools for diverse practical applications, such as environmental pollution monitoring, bioremediation and metabolic process control. | ||
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Revision as of 05:19, 24 September 2013
Aromatics Scouts
A Comprehensive Biosensor Toolkit to Profile Aromatics in Environment
Monitoring aromatics in the environment remains a substantial challenge today. Noting the power of biosensors to enable quick and convenient testing, Peking iGEM have developed a functionally comprehensive biosensor toolkit to profile aromatics in the environment.
Transcriptional regulators that each senses a specific class of aromatics were first bioinformatically determined; they were then utilized to build a comprehensive set of biosensor circuits. Characterization on the detection profiles of individual biosensors and their orthogonality/crosstalk prove that these biosensors are really high-performance to profile aromatics in water.
Moreover, for the ease of practical applications, two types of genetic devices were also developed as plug-ins for biosensors: "Adaptors", a set of conceptually novel devices to convert undetectable chemicals into detectable aromatics, and "Band-pass Filter", a "concentration filter" that allows the detection of analyte concentration within a specific range.
We expect that these novel biosensors, together with the Adaptors and the Band-pass Filter, will serve as intriguing synthetic biological tools for diverse practical applications, such as environmental pollution monitoring, bioremediation and metabolic process control.
We have a date in the database
Auto Sensor Mining
Light of glory shall shed
upon those who see
Biosensors
They will always be there
waiting for our arrival
Plug-ins
My heart beats only for the special you
Band-pass Filter
Though soundless the beatings of wings
do feel the pleasant breeze
Human Practice
