Team:Goettingen/Project
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<p> These bacteria cause serious diseases and are often multi-resistant. c-di-AMP is needed for the control of vital cellular processes in these pathogens because both: lack and accumulation of c-di-AMP, strongly inhibit growth of the bacteria. </p> | <p> These bacteria cause serious diseases and are often multi-resistant. c-di-AMP is needed for the control of vital cellular processes in these pathogens because both: lack and accumulation of c-di-AMP, strongly inhibit growth of the bacteria. </p> | ||
<p> Therefore, any substance that disturbs the homeostasis of the important signaling molecule c-di-AMP and the interaction with its target is of substantial interest to fight human pathogens. The next important step in identifying efficient antibacterial compounds, which either inhibit c-di-AMP biosynthesis or interfere with the essential function of c-di-AMP in the cell, is the development of a powerful screening system. </p> | <p> Therefore, any substance that disturbs the homeostasis of the important signaling molecule c-di-AMP and the interaction with its target is of substantial interest to fight human pathogens. The next important step in identifying efficient antibacterial compounds, which either inhibit c-di-AMP biosynthesis or interfere with the essential function of c-di-AMP in the cell, is the development of a powerful screening system. </p> | ||
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Revision as of 18:34, 26 June 2013