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Team:Goettingen/Project
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===Target: c-di-AMP=== | ===Target: c-di-AMP=== | ||
| - | <p>Since the discovery of penicillin by Alexander Fleming in 1928, antibiotics have marked a major victory of mankind in the battle against infectious diseases. However, after 90 years | + | <p>Since the discovery of penicillin by Alexander Fleming in 1928, antibiotics have marked a major victory of mankind in the battle against infectious diseases. However, after 90 years, the antibiotics are now losing their old time glory: Bacteria acquire resistance against antibiotics and become unbridled. </p> |
<p>We must control the use of antibiotics, meanwhile, we need new antibiotics, which can suffiently eliminate the invaders without hurting the "good" bacteria. Therefore, c-di-AMP, an important, recently discovered signaling molecule in gram-positive bacteria, has come to our sight.</p> | <p>We must control the use of antibiotics, meanwhile, we need new antibiotics, which can suffiently eliminate the invaders without hurting the "good" bacteria. Therefore, c-di-AMP, an important, recently discovered signaling molecule in gram-positive bacteria, has come to our sight.</p> | ||
<p>Out project is to build a screening system targeting c-di-AMP, which could be applied in novel-drug screening. With this system, the level of c-di-AMP in the cell can be visualised and measured. In the moment we are still wokring hard in the lab. To see our progress, please visit [[Team:Goettingen/NoteBook|Our Lab Book]]. | <p>Out project is to build a screening system targeting c-di-AMP, which could be applied in novel-drug screening. With this system, the level of c-di-AMP in the cell can be visualised and measured. In the moment we are still wokring hard in the lab. To see our progress, please visit [[Team:Goettingen/NoteBook|Our Lab Book]]. | ||
Revision as of 22:13, 26 June 2013
