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Team:Imperial College/Modelling beta-amyloid
From 2013.igem.org
Modelling Beta-Amyloid
This is another degradation model we designed to help UCL 2013 iGEM team with their Beta-Amyloid degradation assays. <a href="https://2013.igem.org/Team:UCL/Project/Degradation" target="_blank">Beta-Amyloid Degradation Assays </a> Beta-Amyloid is known as the component of Amyloids Plaque in association with Alzheimer's disease, in which the target of UCL iGEM this year <a href="https://2013.igem.org/Team:UCL/Background/Alzheimers" target="_blank">Alzheimer's disease (AD)</a>. Matrix metallopeptidase 9 (MMP-9) was discovered to be able to degrade Beta-Amyloid that can be potentially used to cure Alzheimer's disease. The model provides information about how efficient is MMP-9 enzyme to degrade Beta-Amyloids base on the assays from UCL team.
Objectives
