Team:Edinburgh/Modeling/Modelling Results

== Effect of nutrient environment on growth rate

We used the whole cell model to make several types of predictions:

Effect of gene modifications on growth rate

We predicted the difference between the growth rate of the unmodified cells and the cells with the plasmid inserted. We did this for three different nutrient environments (represented by different resource influx rates for the model). The resource influx rates were randomly picked and are not aimed to correspond to actual resource environments.

The graphs below show the values of the growth rate over the time of the simulation from the initial state until steady state is reached. The number shown is the final value of the growth rate at steady state. On the left we can see the results for the unmodified cells, and on the right are the results for the cells modified to produce bioethanol. The results are shown for three different nutrient environments (RE1, RE2, RE3).

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Effect of different nutrient environments on productivity