Team:Paris Bettencourt
From 2013.igem.org
Using Escherichia coli as a model organism we are developing and testing different approaches that could contribute to the eradication of tuberculosis.
A phage sensor for detection of sequence specific antibiotic-resistance genes.
A safe, inexpensively, and specific drug screening method aimed for essential mycobacterial metabolic pathway genes.
A stable phage system producing sRNA which silence the production of antibiotic resistance proteins.
E. coli which invade macrophages and kill mycobacteria.
DETECT
TARGET
SABOTAGE
INFILTRATE
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