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Shape-shifting
From 2013.igem.org
Contents |
Shape-shifting Team
Team Bio
Our Project
Abstract
Our aim is to shape the bacteria to fit different molds using the microfluidics system, model the biophysical characteristics of bacterial cell membrane, and see what happens when we switch the cell wall synthesis back on.
News
Weekly Progress
Day 1. June 10th 2013
Morning
We started a discussion of our sub-project, doing some research into project presentation: wiki layout, t-shirt design and possible team logos. We looked at precedents for inspirational ideas.
Afternoon
Learn about Computational Modelling and BioBrick concepts. Decided to start with biophysical modelling of the lipid membrane of Bacillus subtilis and modelling of lipid synthetic pathway. Later in the day, we had a team meeting to discuss aims and progress of our work.
Day 2. June 11th 2013
Morning
Modelling Exercise. Identifying components and species of subtilin biosynthesis pathway. We also sketched down some potential logo ideas and created a shortlist of favorites.
Afternoon
In the afternoon we learned about the differences and similarities between stochastic and deterministic modeling. We also used rule based modeling such as RuleBender and BioNetGen. We changed the parameters and rates of reaction and observed the effects.
Day 3. June 12th 2013
Morning
we continued learning about stochastic and deterministic modeling and we looked at converting the rate parameters in RuleBender. We continued working on the logo.
